Qingping Yao, MD, PhD

Qingping Yao, MD, PhD
Professor, Department of Medicine
Chief, Division of Rheumatology, Allergy and Immunology
Stony Brook University

Clinical Phone: (631) 444-0580
Schedule an Appointment

Dr. Yao graduated and earned his MD from Inner Mongolia Medical College, China in 1984. He trained in Internal Medicine and Rheumatology and obtained his Ph.D at Peking Union Medical College (PUMC) in 1993 and then served as attending rheumatologist and Associate Professor of Medicine in PUMC Hospital, one of the most prestigious medical institutions in China.

Dr. Yao came to America as a visiting scholar in the Division of Rheumatology at Columbia University in 1997. He then served as a research associate and performed research on gene therapy for arthritis in Dr. Paul Robbins' laboratory at the University of Pittsburgh for five years. He retrained in American hospitals, including residency training in Capital Health System, New Jersey and rheumatology fellowship training at University of California, Los Angeles (UCLA) from 2006 to 2008.

Dr. Yao joined the Cleveland Clinic in Ohio and served as a senior rheumatologist in the top-ranked Department of Rheumatic and Immunologic Disease from 2008 to 2015, where he was inaugural Director of the Clinic for Adult Autoinflammatory Diseases. At the Cleveland Clinic, he identified the disease, Yao syndrome (OMIM617321), formerly designated as NOD2-associated autoinflammatory disease.

Dr. Yao joined the Department of Medicine, Stony Brook University in August 2015. He is Professor, Department of Medicine and serves as Chief of the Division of Rheumatology, Allergy and Immunology. He has continued providing specialized care for patients with autoinflammatory diseases/periodic fever syndromes, as well as pursuing clinical and translational study of autoinflammatory diseases. Dr. Yao’s subspecialty interests also include systemic lupus erythematosus, Sjὅgren's syndrome and paraneoplastic rheumatic diseases.


Selected Publications


  1. McDonald C, Shen M, Johnson EE, Kabi A, Yao Q. Alterations in nucleotide-binding oligomerization domain-2 expression, pathway activation, and cytokine production in Yao syndrome. Autoimmunity. 2018; 51(2):53-61.
  2. Li H, Abramova I, Chesoni S, Yao Q. Molecular genetic analysis for periodic fever syndromes: a supplemental role for the diagnosis of adult-onset Still's disease. Clin Rheumatol. 2018 Jun 17. doi: 10.1007/s10067-018-4178-z. [Epub ahead of print]
  3. Hua Y, Shen M, McDonald C, Yao Q. Autophagy dysfunction in autoinflammatory diseases.    J Autoimmun. 2018 Mar; 88:11-20.
  4. Yao Q, Shen B. A Systematic Analysis of Treatment and Outcomes of NOD2-associated Autoinflammatory Disease (Yao syndrome). Am J Med 2017; 130: 365.e13-e18.
  5. Estephan M, Yao Q, Springer J. Case of NOD2-Associated Autoinflammatory Disease Successfully Treated With Sulfasalazine. J Clin Rheumatol. 2017; 23(1):58-59.
  6. Yao Q, Shen M, Fernandez J. NOD2-associated Autoinflammatory Disease and Immune    Deficiency. J Allergy Clin Immunol Pract. 2016; 4(4):780-2.
  7. Witten J, Siles R, Shen B, Yao Q. Triple disease combination: Familial Mediterranean fever, Crohn’s disease and chronic idiopathic urticaria with angioedema. Inflamm Bowel Dis. 2016; 22(3):E12-3.
  8.  Shen M, Tang L, Shi X, Zeng X, Yao Q. NLRP12 Autoinflammatory Disease: a Chinese    Case Series and Literature Review. Clin Rheumatol. 2016 Sep 16. [Epub ahead of print].
  9. Yao Q, Lacbawan F and Li J. Adult autoinflamamtory disease frequency and our diagnostic experience in an Adult Autoinflammatory Clinic. Semin Arthritis Rheum. 2016; 45(5):633-7.
  10. Yao Q, Shen M, McDonald C, Lacbawan F, Moran R, Shen B. NOD2-associated autoinflammatory disease: a large cohort study. Rheumatology (Oxford).  2015 Oct;54 (10):1904-12. 
  11. Yao Q. Nucleotide-binding oligomerization domain containing 2: structure, function, and diseases. Semin Arthritis Rheum. 2013 Aug; 43(1):125-30.
  12. Yao Q, Myles J, Shen B, McDonald C. NOD2-associated autoinflammatory disease: an exploratory study of its pathogenesis. Rheumatology (Oxford). 2014 May; 53(5):958-60.
  13. Yao Q, Su LC, Tomecki KJ, Zhou L, Jayakar B, Shen B. Dermatitis as a characteristic phenotype of a new autoinflammatory disease associated with NOD2 mutations. J Am Acad Dermatol. 2013 Apr; 68(4):624-31.
  14. Yao Q, Ruggieri P, Lowder C. Ocular myositis occurring with NOD2-associated autoinflammatory disease. J Rheumatol. 2013 Oct; 40(10):1768-9.
  15. Yao Q, Schils J. Distal lower extremity swelling as a prominent phenotype of NOD2-associated autoinflammatory disease. Rheumatology (Oxford). 2013 Nov; 52(11):  2095-7.
  16. Yao Q, Piliang M, Nicolacakis K, Arrossi A. Granulomatous pneumonitis associated with adult-onset Blau-like syndrome. Am J Respir Crit Care Med. 2012 Sep 1; 186(5):465-6.
  17. Shen M, Moran R, Tomecki KJ, Yao Q. Granulomatous disease associated with NOD2 sequence variants and familial camptodactyly: An intermediate form of NOD2-associated diseases? Semin Arthritis Rheum. 2015 Dec; 45(3):357-60.
  18. Yao Q, Englund KA, Hayden SP, Tomecki KJ. Tumor necrosis factor receptor associated periodic fever syndrome with photographic evidence of various skin disease and unusual phenotypes: case report and literature review. Semin Arthritis Rheum. 2012 Feb; 41(4):611-7.
  19. Yao Q, Yerian L, Shen B. Missense mutation V20A in the tumor necrosis factor receptor superfamily 1A (TNFRSF1A) gene is associated with tumor necrosis factor receptor-associated periodic syndrome (TRAPS) presenting with periodic gastrointestinal symptoms. Inflamm Bowel Dis. 2011 Jun; 17(6):1445-6.
  20. Yao Q, Zhou L, Cusumano P, Bose N, Piliang M, Jayakar B, Su LC, Shen B. A new category of autoinflammatory disease associated with NOD2 gene mutations. Arthritis Res Ther. 2011; 13(5):R148.
  21. Yao Q, Furst DE. Autoinflammatory diseases: an update of clinical and genetic aspects. Rheumatology (Oxford). 2008 Jul; 47(7):946-51.


Additional information is available below.