Publications

1. Takimoto E, Champion HC, Belardi D, Moslehi J, Mongillo M, Mergia E, Montrose DC, Isoda T, Aufiero K, Zaccolo M, Dostmann WR, Smith CJ, Kass DA.  cGMP catabolism by phosphodiesterase 5A regulates cardiac adrenergic stimulation by NOS3-dependent mechanism. Circ Res.  2005;96:100-9.
2. Dong M, Johnson M, Rezaie A, Ilsley JNM, Nakanishi M, Sanders MM, Forouhar F, Levine J, Montrose DC, Giardina C, Rosenberg DW. Cytosolic Phospholipase A2 Levels Correlate with Apoptosis in Human Colon Tumorigenesis. Clin Cancer Res. 2005;11:2265-71.
3. Montrose DC and Floch MH.  Probiotics Used in Human Studies.  J Clin Gastroenterol.  2005;39:469-84.
4. Floch MH and Montrose DC.  Use of Probiotics in Humans: An Analysis of  the Literature.  Gastroenterol Clin North Am. 2005;34:547-70.
5. Flynn C, Montrose DC, Swank DL, Nakanishi M, Ilsley JN, Rosenberg DW.  Deoxycholic acid promotes the growth of colonic aberrant crypt foci. Mol Carcinog. 2007;46:60-70.
6. Zhao H, Quilley J, Montrose DC, Rajagopalan S, Guan Q, Smith CJ.  Differential effects of phosphodiesterase PDE-3/PDE-4-specific inhibitors on vasoconstriction and cAMP-dependent vasorelaxation following balloon angioplasty. Am J Physiol Heart Circ Physiol. 2007;292:H2973-81.
7.  Klueh U, Kaur M, Montrose DC, Kreutzer DL. Inflammation and glucose sensors: use of dexamethasone to extend glucose sensor function and life  span in vivo. J Diabetes Sci Technol. 2007;1:496-504.
8. Fleming ES, Zajac M, Moschenross DM, Montrose DC, Rosenberg DW,  Cowan AE, Tirnauer JS. Planar spindle orientation and asymmetric cytokinesis in the mouse small intestine. J Histochem Cytochem. 2007;55:1173-80.
9. Nakanishi M, Montrose DC, Clark P, Nambiar PR, Belinsky GS, Claffey KP,  Xu D, Rosenberg DW. Genetic deletion of mPGES-1 suppresses intestinal tumorigenesis. Cancer Res. 2008;68:3251-59.
10. Winnicka B, O'Conor C, Schacke W, Vernier K, Grant CL, Fenteany FH, Pereira FE, Liang B, Kaur A, Zhao R, Montrose DC, Rosenberg DW, Aguila HL, Shapiro LH. CD13 is dispensable for normal hematopoiesis and myeloid cell functions in the mouse. J Leukoc Biol. 2010;88:347-59.
11. Montrose DC, Kadaveru K, Ilsley JNM, Seaman S, Rajan TV, Ramesh M, Nichols FC, Liang BT, Sonin D, Hand AR, Zarini S, Murphy RC, Belinsky GS, Nakanishi M, Rosenberg DW. cPLA2 is Protective against COX inhibitor-induced intestinal damage. Toxicol Sci. 2010;117:122-32.
12. Montrose DC, Horelik NA, Madigan JP, Stoner, GD, Wang LS, Bruno RS,Park HJ, Giardina C, Rosenberg DW. Anti-inflammatory effects of lyophilized black raspberry powder in ulcerative colitis. Carcinogenesis. 2011;32:343-50.
13. Nakanishi M, Menoret A, Tanaka T, Miyamoto S, Montrose DC, Vella A, Rosenberg DW. Selective PGE2 suppression impairs colon carcinogenesis and modifies local mucosal immunity. Cancer Prev Res. 2011;4:1198-208.
14. Makino T*, Jain M*, Montrose DC*, Aggarwal A, Sterling J, Bosworth BP,Milsom JW, Robinson BD, Shevchuk MM, Kawaguchi K, Zhang N, Brown CM, Rivera DR, Williams WO, Xu C, Dannenberg AJ, Mukherjee S. Multiphoton tomographic imaging: a potential optical biopsy tool for detecting  gastrointestinal inflammation and neoplasia. Cancer Prev Res. 2012;5:1280-90. *These authors contributed equally to the study. (Selected for cover art).
15. Montrose DC, Zhou XK, Kopelovich L, Yantiss RK, Karoly ED, Subbaramaiah K, Dannenberg AJ. Metabolic Profiling, a Non-invasive Approach for the Detection of Experimental Colorectal Neoplasia. Cancer Prev Res. 2012;5:1358-67. (Perspective written on this study) (Highlighted as top article for 2012) (Selected for cover art)
16. Montrose DC, Scherl EJ, Bosworth BP, Zhou XK, Jung B, Dannenberg AJ, Hla T. S1P1 localizes to the colonic vasculature in ulcerative colitis and maintains blood vessel integrity. J Lipid Res. 2013;54:843-51.
17. Montrose DC, Nakanishi M, Murphy RC, Zarini S, McAleer JP, Vella AT, Rosenberg DW. The role of PGE2 in intestinal inflammation and tumorigenesis. Prostaglandins Other Lipid Mediat. 2015;116-117:26-36.
18. Cook PJ, Thomas R, Kingsley PJ, Shimizu F, Montrose DC, Marnett  LJ, Tabar VS, Dannenberg AJ, Benezra R.  Cox-2-Derived PGE2 Induces Id1-Dependent Radiation Resistance and Self-Renewal in Experimental Glioblastoma. Neuro-Oncology. 2016;18:1379-89.
19. Montrose DC, Zhou XK, McNally EM, Sue E, Yantiss RK, Gross SS, Leve ND, Karoly ED, Suen CS, Ling L, Benezra R, Pamer EG, Dannenberg  AJ. Celecoxib alters the intestinal microbiota and metabolome in association with reducing polyp burden. Cancer Prev Res. 2016;9:721-31. (Highlighted as top article for 2016) (Selected for cover art)
20. Montrose DC*, Zhou XK, McNally EM, Sue E, Wang H, Nishiguchi R, Verma A, Elemento O, Simpson KW, Yang P, Hla T, Dannenberg  AJ. Colonoscopic-guided pinch biopsies in mice: A useful model for evaluating the roles of host and luminal factors in colonic inflammation. Am J Pathol. 2018; 188:2811-25. *Co-corresponding author.
21. Garibay D, Zaborska KE, Shanahan M, Zheng Q, Kelly KM, Montrose DC, Dannenberg AJ, Miller AD, Sethupathy P, Cummings BP. TGF5 Protects Against Colitis in Mice, but Vertical Sleeve Gastrectomy Increases Colitis Severity. Obes Surg. 2019; 29:1593-01.
22. Wipperman MF, Montrose DC, Gotto AM, Hajjar DP. Mammalian Target of Rapamycin: a metabolic rheostat for regulating adipose tissue function and cardiovascular health. Am J Pathol. 2019; 189:492-501.
23. Montrose DC*, Galluzzi L. Drugging cancer metabolism: Expectations vs. reality. Int Rev Cell Mol Biol. 2019;347:1-26. *Co-corresponding author.
24. Montrose DC, Nishiguchi R, Basu S, Staab HA, Zhou XK, Wang H, Meng L, Johncilla M, Cubillos-Ruiz JR, Morales DK, Wells MT, Simpson KW, Zhang S, Dogan B, Jiao C, Fei Z, Oka A, Herzog JW, Sartor RB, Dannenberg AJ. Dietary Fructose Alters the Composition, Localization and Metabolism of Gut Microbiota in Association with Worsening Colitis. Cell Mol Gastroenterol Hepatol. 2021; 11:525-550.
25. Montrose DC*, Makino T, Basu S, Ito N, Dannenberg AJ. Induction of colitis-associated neoplasia in mice using azoxymethane and dextran sodium sulfate. Methods Cell Biol. 2021; 163:123-135. *Corresponding author.
26. Montrose DC*, Saha S, Foronda M, McNally EM, Zhou XK, Ha T, Krumsiek J, Verma A, Elemento O, Yantiss RK, Chen Q, Gross SS, Galluzzi L, Dow LE, Dannenberg AJ. Exogenous and Endogenous Sources of Serine Contribute to Colon Cancer Metabolism and Growth. Cancer Res. 2021; 81:2275-88. *Corresponding author.
27. Nishiguchi R, Basu S, Staab HA, Ito N, Zhou XK, Wang H, Ha T, Johncilla M, Yantiss RK, Montrose DC, Dannenberg AJ. Dietary Interventions to Prevent High Fructose Diet- associated Worsening of Colitis and Colitis-associated Tumorigenesis in Mice. Carcinogenesis. 2021; 42:842-852.
28. Montrose DC*, Zhou XK, McNally EM, Sue E, Dannenberg AJ. Performing Colonoscopic-Guided Pinch Biopsies in Mice and Evaluating Subsequent Tissue Changes. J Vis Exp. 2021. *Corresponding author.
29. Wojnarowicz PM, Escolano MG, Huang YH, Desai B, Chin Y, Shah R, Xu S, Yadav S, Yaklichkin S, Ouerfelli O, Soni RK, Philip J, Montrose DC, Healey JH, Rajasekhar VK, Garland WA, Ratiu J, Zhuang Y, Norton L, Rosen N, Hendrickson RC, Zhou XK, Iavarone A, Massague J, Dannenberg AJ, Lasorella A, Benezra R. Anti-tumor effects of an ID antagonist with no observed acquired resistance. NPJ Breast Cancer. 2021; 7:58.
30. Basu S, Liu C, Zhou XK, Nishiguchi R, Ha T, Chen J, Johncilla M, Yantiss RK, Montrose DC*, Dannenberg AJ. GLUT5 is a Determinant of Dietary Fructose-mediated Exacerbation of Experimental Colitis. Am J Physiol Gastrointest Liver Physiol. 2021;321:G232-G242. *Co-corresponding author.
31. Buque A, Galluzzi G, Montrose DC. Targeting serine in cancer: Is two better than one? Trends Cancer. 2021;7:668-670.
32. Saha S, Bai JDK, Montrose DC. Induction and Evaluation of T Cell Transfer Colitis. Methods Cell Biol. 2022;168:1-17.
33. Montrose DC* and Galluzzi L. Restored Ketosis Drives Anticancer Immunity in Colorectal Cancer. Cancer Res. 2022;82:1464-1466. Invited commentary. *Co-corresponding author.
34. Buque A, Montrose DC, Galluzzi G. Emergent impact of lifestyle on tumor progression and response to therapy. Int Rev Cell Mol Biol. 2022;373ix-xvii.
35. Connolly-Schoonen J, Biamonte SF, Danowski L, Montrose DC. Modifying Dietary Amino Acids in Cancer Patients. Int Rev Cell Mol Biol. 2022;373:1-36.
36. Ferrara CR, Bai JDK, McNally EM, Lang A, Putzel GG, Zhou XK, Wang H, Lang A, Nagle D, Denoya P, Krumsiek J, Dannenberg AJ, Montrose DC. Microbes Contribute to Chemopreventive Efficacy, Intestinal Tumorigenesis and the Metabolome. Cancer Prev Res. 2022;15:803-814.
37. Ghosh M, Saha S, Li J, Montrose DC, Martinez LA. p53 engages the cGAS/STING cytosolic DNA sensing pathway for tumor suppression. Mol Cell. 2023 Jan 19;83(2):266-280.e6.  
38. Connolly-Schoonen J, Danowski L, Bistricer M, Campo Catalan L, Ailawadi S, Sicinski EM, Schoonen M, Ingram B, Montrose DC. A Pilot Controlled Feeding Trial Modifying Protein Intake in Healthy Subjects to Assess Adherence and the Metabolome. Nutr Cancer. 2023;75(7):1499-1510.
39. Bai JDK, Saha S, Wood MC, Chen B, Li J, Dow LE, Montrose DC. Serine Supports Epithelial and Immune Cell Function in Colitis. Am J Pathol. 2024 Jun;194(6):927-940. 
40. Saha S, Ghosh M, Li J, Wen A, Galluzzi L, Martinez LA, Montrose DC. Serine Depletion Promotes Anti-Tumor Immunity by Activating Mitochondrial DNA-mediated cGAS-STING Signaling. Cancer Res. 2024 Jun 11. doi: 10.1158/0008-5472.CAN-23-1788. Epub ahead of print. PMID: 38861367.