Noted Publications
Evans, J.E. and Hearing, P. Distinct roles of the adenovirus E4 ORF3 protein in viral DNA replication and inhibition of genome concatenation. J. Virol. 77: 5295-5304 (2003).
Lang, S.E. and Hearing, P. The adenovirus E1A oncoprotein recruits the cellular TRRAP/GCN5 histone acetyltransferase complex. Oncogene 22:. 2836-2841 (2003).
Ostapchuk, P. and Hearing, P. Minimal cis-acting elements required for adenovirus genome packaging. J. Virol. 77: 5127-5135 (2003).
Erturk, E., Ostapchuk, P., Wells, S.I., Yang, J., Gregg,, K., Nepveu, A.,Dudley, J.P., and Hearing, P. Binding of CCAAT Displacement Protein, CDP, to adenovirus packaging sequences. J. Virol. 77: 6255-6264 (2003).
Gnatenko DV, Wu Y, Jesty J, Damon AL, Hearing P, Bahou WF. Expression of therapeutic levels of factor VIII in hemophilia A mice using a novel adeno/adeno-associated hybrid virus. Thromb Haemost. 92:317-327 (2004).
Schaley JE, Polonskaia M, and Hearing P. The Adenovirus E4-6/7 Protein Directs Nuclear Localization of E2F-4 via an Arginine-Rich Motif. J Virol. 79:2301-2308 (2005).
Ostapchuk, P., Yang, J., Auffarth, E., and Hearing, P. Functional interaction of the adenovirus IVa2 protein with Ad5 packaging sequences. J. Virol. 79:2831-2838 (2005).
Evans, J.E. and Hearing, P. Relocalization of the Mre11-Rad50-Nbs1 complex by the adenovirus E4-ORF3 protein is required for viral replication. J. Virol. 79:6207-6215 (2005).
Ostapchuk, P. and Hearing, P. Control of Adenovirus Packaging. J. Cell. Biochem., 96: 25-35 (2005).
Ostapchuk, P., Anderson, M., Chandrasekhar, S., and Hearing, P. The L4 22kDa protein plays a role in packaging of the Adenovirus genome. J. Virol. 80:6973-6981 (2006).
Sitaraman, V., Hearing, P., Ward, C.B., Gnatenko, D., Wimmer, E., Mueller, S., Skiena, S., and Bahou, W.F. Computationally-designed AAV Rep 78 is efficiently maintained within an adenovirus vector. Proc. Natl. Acad. Sci. USA 108:14294-14209 (2011). PMCID: PMC3161519
Vink, E.I, Yondola, M.A., Wu, K., and Hearing, P. Adenovirus E4-ORF3-dependent relocalization of TIF1a and TIF1g relies on access to the Coiled-Coil motif. Virol. 422:317-325 (2011). PMCID: PMC3249475
Patsalo, V., Yondola, M.A., Luan, B., Shoshani, I., Kisker, C., Green, D.F., Raleigh, D.P. and Hearing, P. Biophysical and functional analyses suggest that the adenovirus E4-ORF3 protein requires higher-order multimerization to function against PML nuclear bodies. J. Biol. Chem. 287:22573-22583 (2012). PMCID: PMC3391147
Sohn, S.Y. and Hearing, P. Adenovirus regulates sumoylation of Mre11-Rad50-Nbs1 components through a paralog-specific mechanism. J. Virol. 86:9656-9665 (2012). PMCID: PMC3446602
Wu, K., Orozco, D. and Hearing, P. The adenovirus L4-22K protein is multifunctional and an integral component of crucial aspects of infection. J. Virol. 86:10474-10483 (2012). PMCID: PMC3457327
Wu, K., Guimet, D. and Hearing, P. The adenovirus L4-33K protein regulates both late gene expression patterns and viral DNA packaging. J. Virol. 87:6739-6747 (2013). PMCID: PMC3676125
Guimet, D. and Hearing, P. The adenovirus L4-22K protein has distinct functions in the post-transcriptional regulation of gene expression and encapsidation of the viral genome. J. Virol. 87:7688-7699 (2013). PMCID: PMC3700311
See PubMed for a complete list of current publications.
