Stephen Gaudino

 


 

B.S., Biology, Hofstra University
M.S., Integrative Biology, Hofstra University
Ph.D., Molecular Genetics and Microbiology
Advisor: Pawan Kumar
Email: Stephen.Gaudino@stonybrook.edu

Research Interests

I received my M.S. at Hofstra University where I studied how Acinetobacter baylyi utilizes pili to aid in various processes including motility and biofilm production. My current research interests involve studying different symbiotic relationships between humans and bacteria and the molecular mechanisms used by bacteria to establish these relationships. I am also interested in studying how the human immune system responds to such interactions. During my free time, I enjoy playing tennis, cycling, and cooking. 

Awards

Travel Award, Immunology 2021, American Association of Immunologists, May 10-15, virtual meeting.
Irving Abrahams Award for Outstanding Achievement by a Graduate Student, 2021.
Outstanding Poster Award. 2021 Department of Microbiology and Immunology Retreat.
Travel Award, Immunology 2020, American Association of Immunologists (meeting cancelled due to COVID-19 pandemic).
Travel Award, Immunology 2019, American Association of Immunologists, May 9-13, San Diego, CA.
Stony Brook University Graduate Council Fellowship, 2019 - 2022
Stony Brook University Microbiology Scholar Award, 2017
National Science Foundation Predoctoral Fellowship, 2016 - 2019

 

Publications

Gaudino, S.J., Singh, A., Huang, H., Padiadpu, J., Jean-Pierre, M., Kempen, C., Bahadur, T., Shiomitsu, K, Blumberg, R., Shroyer, K.R., Beyaz, S., Shulzhenko, N., Morgun, A., and Kumar, P. (2024). Intestinal IL-22RA1 signaling regulates intrinsic and systemic lipid and glucose metabolism to alleviate obesity-associated disorders. Nature Communications 15(1): 1597.

Lin, X., Gaudino, S.J., Jang, K.K., Bahadur, T., Singh, A., Banerjee, A., Beaupre, M., Chu, T., Wong, H.T., Kim, C.-K., Kempen, C., Axelrad, J., Huang, H, Khalid, S., Shah, Vyom, Eskiocak, O., Parks, O.B., Berisha, A., McAleer, J.P., Good, M., Hoshino, M., Blumberg, R., Bialkowska, A.B., Gaffen, S.L., Kolls, J.K., Yang, V.W., Beyaz, S., Cadwell, K., and Kumar, P. (2022). IL-17RA-signaling in Lgr5+ intestinal epithelial cells induces expression of transcription factor ATOH1 to promote secretory cell lineage commitment. Immunity 55(2): 237-253.

Guadino, S.J., Huang, H., Jean-Pierre, M., Joshi, P., Beaupre, M., Kempen, C., Wong, H.T., and Kumar, P. (2021). Cutting Edge: Intestinal IL-17A Receptor signaling specifically regulates high-fat diet-mediated, microbiota-driven metabolic disorders. Journal of Immunology, doi: 10.4049/jimmunol.2000986.

Lin, X., Tawch, S., Wong, H.T., Roy, S., Gaudino, S., Castillo, P., Elsegeiny, W., Wakabayashi, N., Oury, T.D., Pociask, S., Chen, Kong, McLinskey, N., Melville, P., Syritsyna, O., Coyle, P., Good, M., Awashthi, A., Kolls, J.K., and Kumar, P. (2021). Nrf2 through aryl hydrocarbon receptor regulates IL-22 response in CD4 T cells. Journal of Immunology 206(7): 1540-1548.

Gaudino, S.J., Beaupre, M., Lin, X., Joshi, P., Rathi, S., McLaughlin, P.A., Kempen, C., Mehta, N., Eskiocak, O., Yueh, B., Blumberg, R.S., van der Velden, A.W.M., Shroyer, K.R., Bialkowska, A.B., Beyaz, S., and Kumar, P. (2020). IL-22 receptor signaling in Paneth cells is critical for their maturation, microbiota colonization, Th17-related immune responses, and anti-Salmonella immunity. Mucosal Immunity, doi: 10.1038/s41385-020-00348-5.

Gaudino, S.J., Huang, H., Jean-Pierre, M., Beaupre, M., Lin, X., and Kumar, P. (2019). Cross-talk between antigen presenting cells and T cells impacts intestinal homeostasis, bacterial infections, and tumorigenesis. Frontiers in Immunology, doi 10.3389/fimmu.2019.00360.

Presentations

Gaudino, S., Huang, H., Jena-Pierre, M., Beaupre, M., Lin, X., and Kumar, P. (2019). Intestinal Interleukin (IL)-22Ra1 Signaling Regulates the Reciprocal Cntrol of IL-22 and Onset of High Fat Diet-induced Metabolic Disorders. 2019 Symposium on Harnessing Immunity to Combat Infection and Disease, April 29, Stony Brook University, Stony Brook, NY.

Gaudino, S.J., Huang, H., Jean-Pierre, M., Beaupre, M., Lin, X., and Kumar, P. (2019). Intestinal Interleukin (IL)-22RA1 Signaling Regulates the Reciprocal Control of IL-22 and Onset of High Fat Diet-induced Metabolic Disorders. Immunology 2019, American Association of Immunologists, May 9-13, San Diego, CA.

Lin, X., Gaudino, S., Kolls, J., and Kumar, P. (2019). Nrf2 Selectively Regulates IL-22 and IL-17A Production in Th17 Cells. Immunology 2019, American Association of Immunologists, May 9-13, San Diego, CA.