1. Neurosurgery
  2. The Mofakham Mikell Lab
  3. Publications

Publications

Publications

 

  1. Drakos P, Volteas P, Naeem Z, Asencio AA, Cleri NA, Alkadaa LN, Oganov A, Gammel T, Saadon JR, Bannazadeh M, Tassiopoulos AK, Mikell CB, Rubano J, Pryor A, Spaniolas K, Mofakham S. Aggressive Anticoagulation May Decrease Mortality in Obese Critically Ill COVID-19 Patients. Obes Surg. 2021 Nov 24:1–7. doi: 10.1007/s11695-021-05799-8. Epub ahead of print. PMID: 34816357; PMCID: PMC8610786.
  2. Mofakham S, Liu Y, Hensley A, Saadon JR, Gammel T, Adachi J, Mohammad S, Huang C, Djurić P, Mikell C. Injury to thalamocortical projections following traumatic brain injury results in attractor dynamics for cortical networks (In review).
  3. Mofakham S, Fry A, Adachi J, Stefancin PL, Duong T, Saadon JR, Winans NJ, Sharma H, Feng G, Djuric P, Mikell C. Electrocorticography reveals thalamic control of cortical dynamics following traumatic brain injury. Commun Biol 4. 2021 Oct 21. doi: https://doi.org/10.1038/s42003-021-02738-2
  4. Cosgrove M, Mikell C, Stefancin P, Alkadaa L, Wang Z, Saadon J, Huang C,  Mofakham S. Thalamo-Prefrontal Connectivity Correlates with Early Command Following After Severe Traumatic Brain Injury (In review).
  5. Volteas P, Drakos P, Labropoulos N, Cleri N, Alkadaa L, Asencio A, Oganov A, Gammel T, Mikell III C, Rubano J, Tassiopoulos A, Bannazadeh M, Mofakham S, Comparison of low-molecular-weight heparin versus unfractionated heparin in critically ill COVID-19 patients, Eastern Vascular Surgery (In review). 
  6. Wang Z, Winans NJ, Zhao Z, Cosgrove ME, Gammel T, Saadon JR, Mani R, Ravi B, Fiore SM, Mikell CB, Mofakham S. Agitation following severe traumatic brain injury is a clinical sign of recovery of consciousness. Frontiers in surgery. 2021 Apr 21;8:90.
  7. Zhao Z, Liang JJ, Wang Z, Winans NJ, Morris M, Doyle S, Fry A, Fiore SM, Mofakham S, Mikell CB. Cardiac arrest after severe traumatic brain injury can be survivable with good outcomes. Trauma Surgery & Acute Care Open. 2021 Feb 1;6(1):e000638.
  8. Tassiopoulos AK, Mofakham S, Rubano JA, Labropoulos N, Bannazadeh M, Drakos P, Volteas P, Cleri NA, Alkadaa LN, Asencio AA, Oganov A. D-dimer-driven anticoagulation reduces mortality in intubated COVID-19 patients: a cohort study with a propensity-matched analysis. Frontiers in medicine. 2021 Feb 4;8:45.
  9. Drakos P, Volteas P, Cleri NA, Alkadaa LN, Asencio AA, Oganov A, Pryor A, Talamini M, Rubano J, Bannazadeh M, Mikell CB. Acute Gastrointestinal Injury and Feeding Intolerance as Prognostic Factors in Critically Ill COVID-19 Patients. Journal of Gastrointestinal Surgery. 2021 Apr 27:1-0.
  10. Sosunov A, Wu X, McGovern R, Mikell C, McKhann GM, Goldman JE. Abnormal mitosis in reactive astrocytes. Acta neuropathologica communications. 2020 Dec; 8:1-20.
  11. Smith EH, Horga G, Yates MJ, Mikell CB, Banks GP, Pathak YJ, Schevon CA, McKhann GM, Hayden BY, Botvinick MM, Sheth SA. Widespread temporal coding of cognitive control in the human prefrontal cortex. Nature neuroscience. 2019 Nov;22(11):1883-91.
  12. Winans NJ, Liang JJ, Ashcroft B, Doyle S, Fry A, Fiore SM, Mofakham S, Mikell CB. Modeling the return to consciousness after severe traumatic brain injury at a large academic level 1 trauma center. Journal of neurosurgery. 2019 Jun 14;133(2):477-85.
  13. Mikell CB, Neimat JS. Microelectrode Recording-Based Targeting for Parkinson’s Disease Surgery. InSurgery for Parkinson's Disease 2019 (pp. 55-66). Springer, Cham.
  14. Bari AA, Mikell CB, Abosch A, Ben-Haim S, Buchanan RJ, Burton AW, Carcieri S, Cosgrove GR, D’Haese PF, Daskalakis ZJ, Eskandar EN. Charting the road forward in psychiatric neurosurgery: proceedings of the 2016 American Society for Stereotactic and Functional Neurosurgery workshop on neuromodulation for psychiatric disorders. Journal of Neurology, Neurosurgery & Psychiatry. 2018 Aug 1;89(8):886-96.
  15. Schmitt LI, Wimmer RD, Nakajima M, Happ M, Mofakham S, Halassa MM. Thalamic amplification of cortical connectivity sustains attentional control. Nature. 2017 May;545(7653):219-23.
  16. Ognjanovski N, Schaeffer S, Wu J, Mofakham S, Maruyama D, Zochowski M, Aton SJ. Parvalbumin-expressing interneurons coordinate hippocampal network dynamics required for memory consolidation. Nature communications. 2017 Apr 6;8(1):1-4.
  17. Mofakham S, Fink CG, Booth V, Zochowski MR. Interplay between excitability type and distributions of neuronal connectivity determines neuronal network synchronization. Physical Review E. 2016 Oct 31;94(4):042427.
  18. Mikell CB, Dyster TG, Claassen J. Invasive seizure monitoring in the critically-Ill brain injury patient: current practices and a review of the literature. Seizure. 2016 Oct 1;41:201-5.
  19. Youngerman BE, Chan AK, Mikell CB, McKhann GM, Sheth SA. A decade of emerging indications: deep brain stimulation in the United States. Journal of neurosurgery. 2016 Aug 1;125(2):461-71.
  20. Mikell CB, Sinha S, Sheth SA. Neurosurgery for schizophrenia: an update on pathophysiology and a novel therapeutic target. Journal of neurosurgery. 2016 Apr 1;124(4):917-28.
  21. Brown LT, Mikell CB, Youngerman BE, Zhang Y, McKhann GM, Sheth SA. Dorsal anterior cingulotomy and anterior capsulotomy for severe, refractory obsessive-compulsive disorder: a systematic review of observational studies. Journal of neurosurgery. 2016 Jan 1;124(1):77-89.
  22. Mofakham S. Elucidating the Interplay of Structure, Dynamics, and Function in the Brain’s Neural Networks (Doctoral dissertation).
  23. Smith EH, Banks GP, Mikell CB, Cash SS, Patel SR, Eskandar EN, Sheth SA. Frequency-dependent representation of reinforcement-related information in the human medial and lateral prefrontal cortex. Journal of Neuroscience. 2015 Dec 2;35(48):15827-36.
  24. Mofakham S, Fink CG, Booth V, Zochowski MR. Network heterogeneity and seizure generation. BMC Neuroscience. 2015 Dec;16(1):1-.
  25. McGovern RA, Chan AK, Mikell CB, Sheehy JP, Ferrera VP, McKhann GM. Human substantia nigra neurons encode decision outcome and are modulated by categorization uncertainty in an auditory categorization task. Physiological reports. 2015 Sep;3(9):e12422.
  26. Mofakham S, Zochowski M. Measuring predictability of autonomous network transitions into bursting dynamics. Plos one. 2015 Apr 9;10(4):e0122225.
  27. Banks GP, Mikell CB, Youngerman BE, Henriques B, Kelly KM, Chan AK, Herrera D, Dougherty DD, Eskandar EN, Sheth SA. Neuroanatomical characteristics associated with response to dorsal anterior cingulotomy for obsessive-compulsive disorder. JAMA psychiatry. 2015 Feb 1;72(2):127-35.
  28. Mikell CB, Banks GP, Frey HP, Youngerman BE, Nelp TB, Karas PJ, Chan AK, Voss HU, Connolly ES, Claassen J. Frontal networks associated with command following after hemorrhagic stroke. Stroke. 2015 Jan;46(1):49-57.
  29. Rayshubskiy A, Wojtasiewicz TJ, Mikell CB, Bouchard MB, Timerman D, Youngerman BE, McGovern RA, Otten ML, Canoll P, McKhann II GM, Hillman EM. Direct, intraoperative observation of~ 0.1 Hz hemodynamic oscillations in awake human cortex: implications for fMRI. Neuroimage. 2014 Feb 15;87:323-31.
  30. Mikell CB, Sheehy JP, Youngerman BE, McGovern RA, Wojtasiewicz TJ, Chan AK, Pullman SL, Yu Q, Goodman RR, Schevon CA, McKhann II GM. Features and timing of the response of single neurons to novelty in the substantia nigra. brain research. 2014 Jan 13;1542:79-84.
  31. Chan AK, McGovern RA, Zacharia BE, Mikell CB, Bruce SS, Sheehy JP, Kelly KM, McKhann GM. Inferior short-term safety profile of endoscopic third ventriculostomy compared with ventriculoperitoneal shunt placement for idiopathic normal-pressure hydrocephalus: a population-based study. Neurosurgery. 2013 Dec 1;73(6):951-61.
  32. Karas PJ, Mikell CB, Christian E, Liker MA, Sheth SA. Deep brain stimulation: a mechanistic and clinical update. Neurosurgical focus. 2013 Nov 1;35(5):E1.
  33. Mikell CB, Chan AK, Stein GE, Tanji K, Winfree CJ. Muscle and nerve biopsies: techniques for the neurologist and neurosurgeon. Clinical neurology and neurosurgery. 2013 Aug 1;115(8):1206-14.
  34. Mofakham S, Zochowski M. Neuronal signatures of network transition into bursting. BMC neuroscience. 2013 Jul;14(1):1-.
  35. Sosunov AA, Wu X, McGovern RA, Coughlin DG, Mikell CB, Goodman RR, McKhann GM. The mTOR pathway is activated in glial cells in mesial temporal sclerosis. Epilepsia. 2012 Jun;53:78-86.
  36. Otten ML, Mikell CB, Youngerman BE, Liston C, Sisti MB, Bruce JN, Small SA, McKhann GM. Motor deficits correlate with resting state motor network connectivity in patients with brain tumours. Brain. 2012 Apr 1;135(4):1017-26.
  37. Mikell CB, McKhann GM, Segal S, McGovern RA, Wallenstein MB, Moore H. The hippocampus and nucleus accumbens as potential therapeutic targets for neurosurgical intervention in schizophrenia. Stereotactic and functional neurosurgery. 2009;87(4):256-65.

Conference Abstracts

  1. Oganov A, Gammel T, Mohammad S, Janssen M, Mikell C, Mofakham S. Periodic components of the electroencephalography signal correlate with return of consciousness after traumatic brain injury. American Association of Neurological Surgeons. 2021. 
  2. Saadon J, Yang F, Gammel T, Mohammad S, Rafailovich M, Mikell C, Mofakham S. Real-Time Stress Monitoring Facial Analysis Metrics. American Association of Neurological Surgeons. 2021.
  3. Gammel T, Alkadaa L, Mofakham S, Mikell C. A Review of Current Models of Consciousness and a Toolkit for Clinicians. American Association of Neurological Surgeons. 2021.
  4. Mikell C, Pendleton C, Mofakham S, Asencio A. Thoracic Disc Herniation Associated with Anabolic-Androgenic Steroid Use. American Association of Neurological Surgeons. 2021.
  5. Cosgrove M, Wang Z, Stefancin P, Morris M, Winans N, Saadon J, Fiore S, Mofakham S, Mikell C. Diffusion Tensor Imaging Reveals a Correlation Between Thalamocortical Tract Integrity and Clinical Outcome in Patients with Severe Traumatic Brain Injury. American Association of Neurological Surgeons. 2020.
  6. Mofakham S, Fry A, Adachi J, Saadon J, Gammel T, Mani R, Cosgrove M, Wang Z, Winans N, Servider J, Fiore S, Mikell C. Exploring the Latent State of Coma and Consciousness. American Association of Neurological Surgeons. 2020.
  7. Mani R, Mikell C, Fiore S. Second-Stage Laser Ablation of Tumor Margins for Treatment of Glioblastoma. American Association of Neurological Surgeons. 2020.
  8. Saadon J, Mohammad S, Winans N, Brown D, Gammel T, Adachi J, Mani R, Fiore S, Mikell C, Mofakham S. Unconsciousness in Epilepsy and its Electrophysiological Similarities to Loss of Consciousness After Severe Traumatic Brain Injury. American Association of Neurological Surgeons. 2020.
  9. Gammel T, Wirkowski E, Mikell C, Fiore S. Usefulness of Licox monitor in Moyamoya disease: a case report. American Association of Neurological Surgeons. 2020.
  10. Who Develops Agitated Delirium After Severe Traumatic Brain Injury? A Descriptive Study of Patient Characteristics. American Association of Neurological Surgeons. 2020.