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Eric Burton

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B.S. Biochemistry and Molecular Biology, 2013, Stockton University
Advisor: Dr. Sumita Bhaduri-McIntosh
Email: Eric.Burton@stonybrook.edu

Research Interests

My lab studies gammaherpesviruses, especially focusing on the ways that the virus and the host regulate viral persistence. In particular, my dissertation research revolves around a host complex of proteins responsible for establishing heterochromatin and silencing genes known as the KRAB-ZFP/KAP1 complex. Together, we believe components of this complex suppress the ability of gammaherpesviruses (such as EBV) to emerge from its latent state. In my free time, I enjoy watching Hockey (Go Devils!), reading, and exercising.

Honors and Awards

Award for Oral Presentation, 17th International Symposium on EBV and associated diseases, University of Zürich, Switzerland, August 2016.

T32AI007539 Institutional Training Grant NIAID

Stony Brook University Graduate Council Fellowship, 2013 - 2018

Publications

Li, X.*, Burton, E.M.*, Koganti, S., Zhi, J., Doyle, R., Tenenbaum, S.A., Horn, B., and Bhaduri-McIntosh, S. (2018). KRAB-ZFP repressors enforce quiescence of oncogenic human herpesviruses. Journal of Virology, DOI: 10.1128/JVI.00298-18. *Co-first authors.

Li, X., Burton, E.M., and Bhaduri-McIntosh, S. (2017). Chloroquine triggers Epstein-Barr virus replication through phosphorylation of KAP1/TRIM28 in Burkitt lymphoma cells. PLoS Pathogens 13(3): e1006249. 

Presentations

Burton, E., Koganti, S., Li, X., and Bhaduri-McIntosh, S. Decline in TRIM28/KAP1 Sparks EBV Lytic Activation. 2018 International Conference on EBV and KSHV. July 28 - August 1, Madison, WI.

Burton, E., Koganti, S., and Bhaduri-McIntosh, S. Novel Observations on KAP1/TRIM28 in the context of the Epstein-Barr Virus Lytic Cycle. 17th University of Pennsylvania Herpesvirus Symposium. June 23, 2017.

Burton, E., Koganti, S., Li, X., and Bhaduri-McIntosh, S. Kruppel-associated Box (KRAB)-associated protein (KAP)-1 is Repressed and Post-translationally Modified Early During Epstein-Barr virus Lytic Cycle. 17th International Symposium on Epstein-Barr Virus and Associated Diseases. August 8-12, 2016, Zurich, Switzerland.