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B.S., Biosciences, University of Science and Technology of China |
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Research Interests |
The immune system is able to recognize and eliminate pathogens in infection. If the immune system is exposed to foreign pathogens, it may generate long-lasting immunity, which is called immunological memory. However, it still remains something unknown in the process. My current research interest is to investigate the mechanism on immunological memory. |
| Publications |
Lin, X., Gaudino, S.J., Jang, K.K., Bahadur, T., Singh, A., Banerjee, A., Beaupre, M., Chu, T., Wong, H.T., Kim, C.-K., Kempen, C., Axelrad, J., Huang, H, Khalid, S., Shah, Vyom, Eskiocak, O., Parks, O.B., Berisha, A., McAleer, J.P., Good, M., Hoshino, M., Blumberg, R., Bialkowska, A.B., Gaffen, S.L., Kolls, J.K., Yang, V.W., Beyaz, S., Cadwell, K., and Kumar, P. (2022). IL-17RA-signaling in Lgr5+ intestinal epithelial cells induces expression of transcription factor ATOH1 to promote secretory cell lineage commitment. Immunity 55(2): 237-253. Lin, X., Tawch, S., Wong, H.T., Roy, S., Gaudino, S., Castillo, P., Elsegeiny, W., Wakabayashi, N., Oury, T.D., Pociask, S., Chen, Kong, McLinskey, N., Melville, P., Syritsyna, O., Coyle, P., Good, M., Awashthi, A., Kolls, J.K., and Kumar, P. (2021). Nrf2 through aryl hydrocarbon receptor regulates IL-22 response in CD4 T cells. Journal of Immunology 206(7): 1540-1548. Gaudino, S.J., Beaupre, M., Lin, X., Joshi, P., Rathi, S., McLaughlin, P.A., Kempen, C., Mehta, N., Eskiocak, O., Yueh, B., Blumberg, R.S., van der Velden, A.W.M., Shroyer, K.R., Bialkowska, A.B., Beyaz, S., and Kumar, P. (2020). IL-22 receptor signaling in Paneth cells is critical for their maturation, microbiota colonization, Th17-related immune responses, and anti-Salmonella immunity. Mucosal Immunity, doi: 10.1038/s41385-020-00348-5. Gaudino, S.J., Huang, H., Jean-Pierre, M., Beaupre, M., Lin, X., and Kumar, P. (2019). Cross-talk between antigen presenting cells and T cells impacts intestinal homeostasis, bacterial infections, and tumorigenesis. Frontiers in Immunology, doi 10.3389/fimmu.2019.00360. |
| Presentations |
Gaudino, S., Huang, H., Jena-Pierre, M., Beaupre, M., Lin, X., and Kumar, P. (2019). Intestinal Interleukin (IL)-22Ra1 Signaling Regulates the Reciprocal Cntrol of IL-22 and Onset of High Fat Diet-induced Metabolic Disorders. 2019 Symposium on Harnessing Immunity to Combat Infection and Disease, April 29, Stony Brook University, Stony Brook, NY. Gaudino, S.J., Huang, H., Jean-Pierre, M., Beaupre, M., Lin, X., and Kumar, P. (2019). Intestinal Interleukin (IL)-22RA1 Signaling Regulates the Reciprocal Control of IL-22 and Onset of High Fat Diet-induced Metabolic Disorders. Immunology 2019, American Association of Immunologists, May 9-13, San Diego, CA. Lin, X., Gaudino, S., Kolls, J., and Kumar, P. (2019). Nrf2 Selectively Regulates IL-22 and IL-17A Production in Th17 Cells. Immunology 2019, American Association of Immunologists, May 9-13, San Diego, CA |
