About the Lab
Our lab studies the metabolic and inflammatory mechanisms that drive retinal degenerative diseases, aging-related eye disorders, and ocular fibrosis. We focus on how retinal pigment epithelial (RPE) cells, immune cells, endothelial cells, and fibroblasts interact—particularly through metabolic reprogramming, inflammation, and epigenetic changes. Current research targets the distinct yet interconnected pathways in wet and dry age-related macular degeneration (AMD), as well as ischemic conditions like diabetic retinopathy and retinopathy of prematurity. Using advanced tools such as spatial transcriptomics, single-cell sequencing, and optical imaging, we aim to map cell-specific pathways and intercellular communication that drive disease. Ultimately, our goal is to discover therapeutic targets to preserve vision and reveal broader systemic disease mechanisms through eye-based research.
Primary Investigator
Dr. Yang's research focuses on metabolism and inflammation in retinal diseases.
Lab Members
Get to know the people in our lab, who make up our multidisciplinary research team.
Publications
Explore our recent research findings published in peer-reviewed journals.
Lab Events
Get to know the people in our lab, who make up our multidisciplinary research team.
Research Resources
Explore our recent research findings published in peer-reviewed journals.
We welcome collaborations across disciplines and invite enthusiastic undergraduate students, graduate students, MD/PhD trainees, ophthalmology residents and fellows, and postdocs to join our team. Join us!
Qiuhua Yang Lab
The Department of Pharmacological Sciences,
Stony Brook University,
Basic Science Tower,
Office Room 8-183, Lab Room 8-120
Email: Qiuhua.Yang@stonybrook.edu