Helen Fox, PhD

Assistant Professor of Psychiatry

Phone: (631) 638-0057











BSc (Hons) PsychologyUniversity of Portsmouth, UK1996
PhD in PsychologyUniversity of East London, UK2002
Postdoctoral FellowUniversity of East London, UK2002
Postdoctoral AssociateYale University, CT2003
Research ScientistYale University, CT2006
Assistant ProfessorYale University, CT2011
Assistant ProfessorStony Brook University, NY2016
Research Interests:

Stress and immune system adaptations in individuals using alcohol, cocaine, opioids and club drugs (including synthetic marijuana and synthetic cathinone derivatives)

Gender and addiction

Development of medications for addiction

Teratogenic effects of substance use
Current Research:

Principal Investigator, NIAAA (R21AA024880): Guanfacine to Reduce Relapse Risk in Women With Alcohol Use Disorder (AUD)

Principal Investigator, NIAAA (K02AA23566):Cognitive Targets for Medications Development in Early Abstinent Alcoholics

Representative Publications:

Fox, H.C., Milivojevic, V., Angarita, A.G., Stowe, R., Sinha, R., (in press) Peripheral immune system suppression in early abstinent alcoholics: links to stress and cue-related craving. Journal of Psychopharmacology.

Parrott, A.C., Downey, L.A., Roberts, C.A., Montgomery, C., Bruno, R., Fox, H. C., (in press) Recreational MDMA (3, 4-methylenedioxymethamphetamine;   ‘Ecstasy’): current perspective and future research prospects. Journal of Psychopharmacology

Milivojevic, V., Ansell, E.B., Simpson, C., Siedlarz, K., Sinha, R., Fox, H.C. (2017) Peripheral immune system adaptations and motivation for alcohol in non-dependent problem drinkers. Alcoholism: Clinical and Experimental Research, 41(3):585-595

Fox, H.C., Sofuoglu, M., Sinha, R., (2015) Guanfacine enhances inhibitory control and attentional shifting in early abstinent cocaine dependent individuals. Journal of Psychopharmacology 29(3):312-23.

Milivojevic, V., Sinha, R., Sofuoglu, M., Fox, H.C. (2014).  Effects of endogenous and exogenous progesterone on emotional intelligence in cocaine dependent men and women who also abuse alcohol. Human Psychopharmacology: Clinical and Experimental. 29(6):589-98

Fox, H.C., Sinha, R. (2014). The role of guanfacine as a therapeutic agent to address stress- related pathophysiology in cocaine dependent individuals. Advances in Pharmacology, 69:217-65

Fox, H.C., Morgan, P.T., Sinha, R., (2014). Sex Differences in Guanfacine Effects on Drug Craving and Stress Arousal in Cocaine-Dependent Individuals. Neuropsychopharmacology, 39(6):1527-37

Fox, H.C., Sofuoglu, M., Morgan, P.T., Tuit, K.L., Sinha, R. (2013). The Effects of Exogenous Progesterone on drug craving and stress arousal in cocaine dependence: Impact of gender and cue type. PNEC. 38(9):1532-44

Fox, H.C., Seo, D., Tuit, K., Hansen, J., Kimmerling, A., Morgan, P.T., Sinha, R. (2012). Guanfacine effects on stress, drug craving and prefrontal activation in cocaine dependent individuals: preliminary findings. J Psychopharmacol. 26(7):958-72

 Fox, H.C., Anderson, G.M., Tuit, K., Hansen, J., Kimmerling, A., Siedlarz, K.M., Morgan, P.T., Sinha, R. (2012). Prazosin effects on stress- & cue-induced craving and stress response in alcohol-dependent individuals: preliminary findings. Alcohol Clin Exp Res. 36(2):351-60.

Fox, H.C., Tuit, K.L., Sinha, R. (2013). Stress system changes associated with marijuana dependence increase craving for alcohol & cocaine. Human Psychopharm. 28(1):40-53

Hyman, S., Fox, H.C., Sinha, R. (2007). Stress and drug-cue induced craving in opioid dependent individuals on Naltrexone Exp and Clin. Psychopharmacology. 15(2)134-43.