Greg Perlman, PhD

Greg Perlman, PhD

Assistant Professor of Psychiatry and Behavioral Health

Office: (631) 638-1922

Email: Greg.Perlman@stonybrookmedicine.edu

Address:
Renaissance School of Medicine, Stony Brook University
Department of Psychiatry and Behavioral Health
101 Nicolls Rd
HSC 10-60G
Stony Brook, NY 11794

Board Certification

Licensed clinical psychologist in NY

Education

PhD, University of Minnesota-Twin Cities, 2011

Research Interests

My research integrates developmental psychopathology with neuroscience to identify novel strategies for prevention and treatment of psychiatric disorders. This integrative approach has led me utilize diverse methods in my research to test research hypotheses, including structural and functional magnetic resonance imaging (MRI), neuromelanin-sensitive MRI, event-related potentials, multi-dimensional behavioral phenotypes, and longitudinal and genetically informed study designs.

My current R01-funded research utilizes multimodal assessment, including functional (e.g., fMRI), molecular-based (e.g., neuromelanin MRI), and clinical (e.g., self-reports, rating scales) measurements within a prospective/longitudinal study design. Another focus of my research is to identify predictors, as well as putative consequences, of adolescent-onset drug abuse and depression. This research considers several potential pathways (neural, personality, familial, stress, etc.) that develop over several years, as well as interactions between pathways.  In addition, my expertise in assessment has allowed me to contribute to several NIH-funded projects as a diagnostician and psychiatric rater in diverse age groups (i.e., youth and adults) and diagnostic groups (pervasive developmental disorders, mood disorders, psychotic disorders, and substance use disorders). 

  • Developmental pathways model of depression heterogeneity, NIMH R01MH133652, Co-Investigator
  • Neuromelanin MRI: A tool for non-invasive investigation of dopaminergic abnormalities in adolescent substance use. NIDA R01DA057268. Principal Investigator.
  • Neuromelanin-sensitive MRI: A novel method for assessing dopamine function in adolescent substance users.  NARSAD Young Investigator Award.  Principal Investigator.
  • Neuromelanin sensitive MRI as a novel, non-invasive index of dopamine function in adolescent-onset substance users. R21DA049041.  Principal Investigator.
  • Personality and Biological Predictors of Resiliency to Chronic Stress among High-Achieving Adults.  National Aeronautics and Space Administration.  Principal Investigator.
  • NARSAD Young Investigator Award.  Neural Markers for Schizophrenia and Psychotic Mood Disorder: A Family Study.  Principal Investigator.
  • Perlman, G., Kotov, R., Wengler, K., Moeller, S. J., Horga, G., Abi-Dargham, A., & Klein, D. N. (2025). Neuromelanin-Sensitive MRI Contrast and Chronic Depression in Young Women. JAMA Network Open, 8(9)
  • Perlman, G., Wengler, K., Moeller, S. J., Kotov, R., Klein, D. N., Weinstein, J. J., ... & Abi-Dargham, A. (2024). Association of neuromelanin-sensitive MRI signal with lifetime substance use in young women. American Journal of Psychiatry, 181(11), 997-1005.