Nancy C. Reich Marshall: Publications

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Noted Publications

Ischenko, I., S. D'Amico, M. Rao, J. Lin, M.J. Hayman, S. Powers, O. Petrenko and N.C. Reich. KRAS drives immune evasion in a genetic model of pancreatic cancer (2021) Nature Communications, Mar 5;12(1):1482.

Petrenko, O., J. Li, V. Cimica, P. Mena-Taboada, HY., Shin, S. D'Amico and N.C. Reich. IL-6 promotes MYC-induced B cell lymphomagenesis independent of STAT3 (2021) PLOS One, Mar 2; 16(3): e0247394.

Prokunia-Olsson, L., N. Alphonse, R.E. Dickerson, J.E. Durbin, J.S. Glenn, R. Hartmann, S.V. Kotenko, H.M. Lazear, T.R. O’Brien, C. Odendall, I.O. Onabajo, H. Pionkivska, D.M. Santer, N.C. Reich, A. Wack,and I. Zanoni (2020) COVID-19 and emerging viral infections: The case for interferon lambda. Journal of Experimental Medicine, 217(5):e20299653.

D’Amico, S., J. Shi, B.L. Martin, H.C. Crawford, O. Petrenko, and N.C. Reich (2018) STAT3 is a master regulator of epithelial identitiy and KRAS-driven tumorigenicity. Genes & Development Sep 1;32(17-18):1175-1187. 

Stawowczyk, M., S. Naeem, V. Montoya, D.P. Baker, J. Konopka  and N.C. Reich (2018) Pathogenic effects of IFIT2 and interferon-β during fatal systemic Candida albicans infection, mBio, Apr 17;9(2): 365-18.

Foreman, H-C, J. Armstrong, A. Santana, L.T. Krug, and N.C. Reich (2017) The replication and transcription activator of murine gammaherpesvirus 68 cooperatively enhances cytokine-activated, STAT3-mediated gene expression. Journal of Biological Chemistry, 292:16257-16266.

Reddy, S., HC. Foreman, T. Ozula, GH. Park, V. Poli, N.C. Reich, and L.T. Krug (2016) Ablation of STAT3 in the B cell compartment restricts gammaherpesvirus latency in vivo, mBio, v.7(4):e00723-16.

Shin, HY. and N.C. Reich (2013) Dynamic trafficking of STAT5 depends on an unconventional nuclear localization signal,Journal Cell Science, 126: 3333-3343.

Reich, N.C. (2013) STATs get their move on. JAKSTAT, 2:e27080

Gao, Y., V. Cimica, and N.C. Reich (2012) Suppressor of cytokine signaling 3 inhibits breast tumor kinase activation of STAT3, Journal of Biological Chemistry, 287: 20904-12.

Foreman, H-C, S. Van Scoy, T-F. Cheng, and N.C. Reich, (2012) Activation of Interferon Regulatory Factor 5 in Innate Immune Signaling by Site Specific Phosphorylation, PLoS One. 2012;7(3):e33098

Brzostek-Racine, S., C. Gordon, S. Van Scoy , and N.C. Reich (2011) The DNA Damage Response Induces IFN. Journal of Immunology, 187:5336-45.

Cimica, V., H.C. Chen, J.K. Iyer, and N.C. Reich (2011) Dynamics of the STAT3 Transcription Factor: Nuclear Import Dependent on Ran and Importin-b1, PLoS One 6(5):e20188.

Stawowczyk, M., Van Scoy, S, Kumar, PK and Reich NC 2011. The interferon stimulated gene 54 promotes apoptosis. Journal of Biological Chemistry, 286:7257-66.

Chen, HC and Reich NC 2010. Live cell imaging reveals continuous STAT6 nuclear trafficking. Journal of Immunology 185:64-70.

Reich, NC 2009. STAT3 revs up the powerhouse. Science Signaling 2:pe61.

Andersen, JS., VanScoy, S, Cheng, T-F,  Gomez, D and Reich, NC.  2008. IRF-3-dependent and augmented target genes during viral infection. Genes and Immunity, 9:168-175.

Iyer, J and Reich, NC.  2008. Constitutive Nuclear Import of Latent and Activated STAT5a by its Coiled Coil Domain, FASEB J., 22:391-40.

Reich NC, Liu L. 2006. Tracking STAT nuclear traffic. Nat Rev Immunol. Aug;6(8):602-12.

Cheng TF, Brzostek S, Ando O, Van Scoy S, Kumar KP, Reich NC. 2006. Differential activation of IFN regulatory factor (IRF)-3 and IRF-5 transcription factors during viral infection. J Immunol. Jun 15;176(12):7462-70.

Liu L, Gao Y, Qiu H, Miller WT, Poli V, Reich NC. 2006. Identification of STAT3 as a specific substrate of breast tumor kinase. Oncogene. Aug 10;25(35):4904-12.

Gilbert, M.M., B.K. Weaver, and N.C. Reich. 2005. A novel functional activator of the Drosophila JAK/STAT pathway, unpaired2, is revealed by an in vivo reporter of pathway activation. Mech Development, 122: 939-948.

Liu, L., K. McBride, and N.C. Reich. 2005. STAT3 import is independent of tyrosine phosphorylation and mediated by importin-a3, Proc Natl Acad Sci USA, 102:8150-8155.

Banninger, G. and N.C. Reich 2004. STAT2 nuclear trafficking. J. Biol. Chem.. 279: 39199-206.

Gomez, D. and N.C. Reich, 2003. Stimulation of Primary Human Endothelial Cell Proliferation by IFN-alpha, J. Immunology 170: 5373-5381

McBride, K., G. Banninger, C. McDonald and N.C. Reich. 2002. Regulated nuclear import of the STAT1 transcription factor by direct binding to importin-a5, EMBO J., in press

Faruqi. T.R., D. Gomez, X. Bustelo, D. Bar-Sagi and N.C. Reich. 2001. Rac1 mediates STAT3 activation by autocrine IL-6. Proc Natl Acad Sci USA, 98:9014-9019

Weaver, B., O. Ando, K.P. Kumar and N.C. Reich. 2001. Apoptosis promoted by the dsRNA activated factor (DRAF1) during viral infection independent of the action of interferon or p53. FASEB J., 15:501-551

McBride, K.E., C. McDonald, and N.C. Reich. 2000. Nuclear export signal located within the DNA-binding domain of the STAT1 transcription factor. EMBO J. 19:6196-6206.

Kumar, K.P., K. McBride, B. Weaver, C. Dingwall, and N.C. Reich. 2000. Regulated nuclear-cytoplasmic localization of interferon regulatory factor-3 subunit of the dsRNA activated transcription factor, DRAF1. Mol. & Cell. Biol. 20:4159-4168.

McDonald, C. and N.C. Reich. 1999. Cooperation of the transcriptional coactivators CBP/p300 with STAT6. J. Interferon & Cytokine Res. 19:711-722.

Weaver, B.K., K.P. Kumar and N.C. Reich. 1998. Interferon Regulatory Factor 3 and CREB-Binding Protein/p300 are Subunits of the dsRNA Activated Transcription Factor, DRAF1. Mol. & Cell. Biology 18:359-368.

Martinez-Moczygemba, M., M.J. Gutch, D. French and N.C. Reich. 1997. Distinct STAT Structure Promotes Interaction of STAT2 with the p48 Subunit of the Interferon-a Stimulated Transcription Factor, ISGF3. J. Biol. Chem. 272:200070-200076.

Kotanides, H. and N.C. Reich. 1996. Interleukin-4 Induced STAT6 Recognizes and Activates a Target Site in the Promoter of the Interleukin-4 Receptor Gene. J. Biol. Chem. 271:25555-25561.

Gilmour, K.C., R. Pine and N.C. Reich. 1995. Interleukin-2 Activates STAT5 (Mammary Gland Factor) and Specific Gene Expression in T Lymphocytes. Proc. Natl. Acad. Sci. USA 92:10772-10776. 

Daly, C. and N.C. Reich. 1995. Characterization of dsRNA Activated Factors (DRAFs) as Positive Regulators of Interferon-a Stimulated Genes. J. Biol. Chem. 270:23739-23746. 

Gilmour, K.C. and N.C. Reich. 1994. Receptor to Nucleus Signaling by Prolactin and Interleukin-2 Via Activation of Latent DNA-Binding Factors. Proc. Natl. Acad. Sci. USA 91:6850-6854. 

Kotanides, H. and N.C. Reich. 1993. Tyrosine Phosphorylation is Required for Rapid Activation of a DNA-Binding Factor by Interleukin-4. Science 262:1265-1267. 

Gutch, M.J., C. Daly, and N.C. Reich. 1992. Tyrosine Phosphorylation is Required for Activation of an a-Interferon Stimulated Transcription Factor. Proc. Natl. Acad. Sci. USA 89:11411-11415.

Reich, N.C., B. Evans, D. Levy, D. Fahey, E. Knight, Jr, and J.E. Darnell, Jr. 1987. Interferon-induced transcription of a gene encoding a 15kDa protein depends on an upstream enhancer element. Proc. Natl. Acad. Sci. USA 84:6394-6398.

Reich, N.C. and A.J. Levine. 1984. Growth regulation of a cellular tumor antigen, p53, in non-transformed cells. Nature 308:199-201.

See PubMed for a complete list of current publications.