Over 500 18F and 150 11C radiopharmaceuticals have been characterized in vivo, a significant number used as probes of biological systems, with applications in oncology, cardiology, neurology, psychiatry and drug development.1 PET tracers are designed to be specific for a defined transport or receptor system, enabling the probing of basic biochemical processes in real-time.
Under the oversight of Professor Wenchao Qu, PhD., our radiochemistry facilities specialize in the synthesis, development, and characterization of short-lived positron-emitting radiopharmaceuticals.

Bahl Radiochemistry

Clean lab

  1. Cyclotron Facility
  2. The GMP Radiosynthesis Laboratory is dedicated to the development and production of GMP-grade radiopharmaceuticals to support preclinical and clinical PET imaging at Stony Brook University.
  3. QC laboratory is designed to analyze and assure radiopharmaceutical quality and data.
  4. Metabolite Lab is equipped with state-of-the-art analytical instruments fully capable of ex vivo blood sampling analysis, including baseline, post-injection and metabolite radiochemical data.

Facility for Experimental Radiopharmaceutical Manufacturing (FERM)

This ISO class 7, GMP-grade laboratory focuses on drug development of novel PET radiopharmaceuticals in support of preclinical PET research at Stony Brook University. It was also designed with the capability for radiopharmaceutical shipping to external collaborators.
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PET ex vivo Radiometabolite Laboratory (PERL)

The PET ex vivo Radiometabolite Laboratory (PERL) is dedicated to the ex vivo analysis of blood and other tissue samples to support clinical PET imaging with facilities for organic chemistry, radiosynthesis and radiotracer validation. Services provided include baseline and post-injection blood chemistry; assay of whole blood, serum, or plasma radioactivity; ex vivo analysis of radiopharmaceuticals and their metabolites in both blood and tissue samples.
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Dose calibrator

1For more information: visit the NIH MICAD database

List or Radiopharmaceuticals

Currently In Use; Active Protocols


Target Molecules or Biological Processes

Application Area(s)


Activated T cells

Immunotherapy in Oncology


Amyloid β plaques in brain

Dementia, Normal Aging


Tau fibrillary tangles in brain

Dementia, Normal Aging


k opioid receptors in brain

Psychiatry (Schizophrenia, Depression, Substance Use)


Vesicular acetylcholine transporter in brain

Psychiatry, Neurology, Dementia and Normal Aging


Translocator Protein in brain

Neuroinflammation; Activated Microglia


Metabotropic Glutamate Receptor 5 in brain



Amyloid β plaques in brain

Dementia, Normal Aging


Synaptic  vesicle protein 2A in brain

Synaptic Density (Psychiatry, Neurology, Epiliepsy)


Cyclooxegenase-1 in brain


Currently in the Development Pipeline


Target Molecules or Biological Processes

Application Area(s)


Tau fibrillary tangles in brain

Dementia, Normal Aging


Monoamine Oxidase-B

Dementia, Reactive Astrogliosis


Muscarinic receptors type 1 and 4 in brain

Psychiatry (Psychotic Disorders, Depression, Substance Use)


Dopamine type D2 and D3 receptors in brain

Psychiatry and Neurology (Psychotic Disorders, Parkinson’s Disease)