A. Senior / Corresponding or First Author Publications
D'Amico, S., Dar, U., Eckberg, K., Weisser, I., Hossain, C., Bronstein, R., & Aboudehen, K. (2026). Loss of Snhg5 disrupts cell-cycle regulation without altering cystogenesis in a mouse model of polycystic kidney disease. Sci Rep.
Weisser, I., Eckberg, K., D'Amico, S., Buttram, D., & Aboudehen, K. (2024). Ablation of Long Noncoding RNA Hoxb3os Exacerbates Cystogenesis in Mouse Polycystic Kidney Disease. J Am Soc Nephrol, 35(1), 41-55.
Eckberg, K., Weisser, I., Buttram, D., Somia, N., Igarashi, P., & Aboudehen, K. S. (2022). Small hairpin inhibitory RNA delivery in the metanephric organ culture identifies long noncoding RNA Pvt1 as a modulator of cyst growth. Am J Physiol Renal Physiol, 323(3), F335-F348.
Aboudehen, K. (2020). Regulation of mTOR signaling by long non-coding RNA. Biochim Biophys Acta Gene Regul Mech, 1863(4), 194449.
Aboudehen, K., Farahani, S., Kanchwala, M., Chan, S. C., Avdulov, S., Mickelson, A., Lee, D., Gearhart, M. D., Patel, V., Xing, C., & Igarashi, P. (2018). Long noncoding RNA Hoxb3os is dysregulated in autosomal dominant polycystic kidney disease and regulates mTOR signaling. Journal of Biological Chemistry, 293(24), 9388-9398.
Aboudehen, K., Noureddine, L., Cobo-Stark, P., Avdulov, S., Farahani, S., Gearhart, M. D., Bichet, D. G., Pontoglio, M., Patel, V., & Igarashi, P. (2017). Hepatocyte Nuclear Factor-1beta Regulates Urinary Concentration and Response to Hypertonicity. J Am Soc Nephrol, 28(10), 2887-2900.
Aboudehen, K., Kim, M. S., Mitsche, M., Garland, K., Anderson, N., Noureddine, L., Pontoglio, M., Patel, V., Xie, Y., DeBose-Boyd, R., & Igarashi, P. (2016). Transcription Factor Hepatocyte Nuclear Factor-1beta Regulates Renal Cholesterol Metabolism. J Am Soc Nephrol, 27(8), 2408-2421.
Aboudehen, K., Hilliard, S., Saifudeen, Z., & El-Dahr, S. S. (2012). Mechanisms of p53 activation and physiological relevance in the developing kidney. Am J Physiol Renal Physiol, 302(8), F928-940.
B. Co-Authored Publications
Ramalingam, H., Alvarez, J., Flaten, A., Cobo-Stark, P., Foster, N., Grilli, E., Lakhia, R., Aboudehen, K., Carroll, T., & Patel, V. (2025). An RNA transmethylation pathway governs kidney nephrogenic potential. Nat Commun, 16(1), 4930.
Piret, S. E., Aboudehen, K., & Agrawal, S. (2025). Evolving Understanding of RNA Biology in Kidney Disease. J Am Soc Nephrol.
Lakhia, R., Yheskel, M., Flaten, A., Ramalingam, H., Aboudehen, K., Ferre, S., Biggers, L., Mishra, A., Chaney, C., Wallace, D. P., Carroll, T., Igarashi, P., & Patel, V. (2020). Interstitial microRNA miR-214 attenuates inflammation and polycystic kidney disease progression. Jci Insight, 5(7).
Kompatscher, A., de Baaij, J. H. F., Aboudehen, K., Farahani, S., van Son, L. H. J., Milatz, S., Himmerkus, N., Veenstra, G. C., Bindels, R. J. M., & Hoenderop, J. G. J. (2018). Transcription factor HNF1beta regulates expression of the calcium-sensing receptor in the thick ascending limb of the kidney. Am J Physiol Renal Physiol, 315(1), F27-F35.
Chan, S. C., Zhang, Y., Shao, A., Avdulov, S., Herrera, J., Aboudehen, K., Pontoglio, M., & Igarashi, P. (2018). Mechanism of Fibrosis in HNF1B-Related Autosomal Dominant Tubulointerstitial Kidney Disease. J Am Soc Nephrol, 29(10), 2493-2509.
Kompatscher, A., de Baaij, J. H. F., Aboudehen, K., Hoefnagels, A., Igarashi, P., Bindels, R. J. M., Veenstra, G. J. C., & Hoenderop, J. G. J. (2017). Loss of transcriptional activation of the potassium channel Kir5.1 by HNF1beta drives autosomal dominant tubulointerstitial kidney disease. Kidney Int, 92(5), 1145-1156.
Hajarnis, S., Lakhia, R., Yheskel, M., Williams, D., Sorourian, M., Liu, X., Aboudehen, K., Zhang, S., Kersjes, K., Galasso, R., Li, J., Kaimal, V., Lockton, S., Davis, S., Flaten, A., Johnson, J. A., Holland, W. L., Kusminski, C. M., Scherer, P. E., Patel, V. (2017). microRNA-17 family promotes polycystic kidney disease progression through modulation of mitochondrial metabolism. Nat Commun, 8, 14395.
Lakhia, R., Hajarnis, S., Williams, D., Aboudehen, K., Yheskel, M., Xing, C., Hatley, M. E., Torres, V. E., Wallace, D. P., & Patel, V. (2016). MicroRNA-21 Aggravates Cyst Growth in a Model of Polycystic Kidney Disease. J Am Soc Nephrol, 27(8), 2319-2330.
Hajarnis, S. S., Patel, V., Aboudehen, K., Attanasio, M., Cobo-Stark, P., Pontoglio, M., & Igarashi, P. (2015). Transcription Factor Hepatocyte Nuclear Factor-1beta (HNF-1beta) Regulates MicroRNA-200 Expression through a Long Noncoding RNA. Journal of Biological Chemistry, 290(41), 24793-24805.
Williams, S. S., Cobo-Stark, P., Hajarnis, S., Aboudehen, K., Shao, X., Richardson, J. A., Patel, V., & Igarashi, P. (2014). Tissue-specific regulation of the mouse Pkhd1 (ARPKD) gene promoter. Am J Physiol Renal Physiol, 307(3), F356-368.
El-Dahr, S., Hilliard, S., Aboudehen, K., & Saifudeen, Z. (2014). The MDM2-p53 pathway: multiple roles in kidney development. Pediatr Nephrol, 29(4), 621-627.
Saifudeen, Z., Liu, J., Dipp, S., Yao, X., Li, Y., McLaughlin, N., Aboudehen, K., & El-Dahr, S. S. (2012). A p53-Pax2 pathway in kidney development: implications for nephrogenesis. PLoS One, 7(9), e44869.
Hilliard, S., Aboudehen, K., Yao, X., & El-Dahr, S. S. (2011). Tight regulation of p53 activity by Mdm2 is required for ureteric bud growth and branching. Developmental Biology, 353(2), 354-366.
Goldfarb, A. H., Garten, R. S., Chee, P. D., Cho, C., Reeves, G. V., Hollander, D. B., Thomas, C., Aboudehen, K. S., Francois, M., & Kraemer, R. R. (2008). Resistance exercise effects on blood glutathione status and plasma protein carbonyls: influence of partial vascular occlusion. European Journal of Applied Physiology, 104(5), 813-819.
El-Dahr, S. S., Aboudehen, K., & Saifudeen, Z. (2008). Transcriptional control of terminal nephron differentiation. Am J Physiol Renal Physiol, 294(6), F1273-1278.
El-Dahr, S. S., Aboudehen, K., & Dipp, S. (2008). Bradykinin B2 receptor null mice harboring a Ser23-to-Ala substitution in the p53 gene are protected from renal dysgenesis. Am J Physiol Renal Physiol, 295(5), F1404-1413.
Howard, G. T., Mackie, R. I., Cann, I. K., Ohene-Adjei, S., Aboudehen, K. S., Duos, B. G., & Childers, G. W. (2007). Effect of insertional mutations in the pueA and pueB genes encoding two polyurethanases in Pseudomonas chlororaphis contained within a gene cluster. Journal of Applied Microbiology, 103(6), 2074-2083.
Doughty, M. B., Aboudehen, K., Anderson, G., Li, K., Moore, B., 2nd, & Poolson, T. (2004). Side-chain conformational restriction in template-competitive inhibitors of E. coli DNA polymerase I Klenow fragment: synthesis, structural characterization and inhibition activity. Nucleosides Nucleotides Nucleic Acids, 23(11), 1751-1765.
Kraemer, R. R., Aboudehen, K. S., Carruth, A. K., Durand, R. T., Acevedo, E. O., Hebert, E. P., Johnson, L. G., & Castracane, V. D. (2003). Adiponectin responses to continuous and progressively intense intermittent exercise. Medicine & Science in Sports & Exercise, 35(8), 1320-1325.
ORCID: https://orcid.org/0000-0003-4975-464X
Pubmed: https://www.ncbi.nlm.nih.gov/myncbi/14KZgwo9wankz/bibliography/public/