Publications & Presentations

Publications in 2023:

  1. Roles of Krüppel-like transcription factors KLF6 and KLF15 in proximal tubular metabolism. Piret SE.Nephron. 2023 Jun 1. doi: 10.1159/000531336. Online ahead of print.PMID: 37263229 Free article. Review.
  2. Dialysis resource allocation in critical care: the impact of the COVID-19 pandemic and the promise of big data analytics. Koraishy FM, Mallipattu SK.Front Nephrol. 2023 Oct 26;3:1266967. doi: 10.3389/fneph.2023.1266967. eCollection 2023.PMID: 37965069 Free PMC article. Review.
  3. The association of post-traumatic stress disorder with glomerular filtration rate decline. Koraishy FM, Cohen BE, Scherrer JF, Whooley M, Hajagos J, Robinson-Cohen C, Hou W.Nephrology (Carlton). 2023 Mar;28(3):181-186. doi: 10.1111/nep.14140. Epub 2023 Jan 20.PMID: 36594760
  4. Geographic and Temporal Trends in COVID-Associated Acute Kidney Injury in the National COVID Cohort Collaborative. Yoo YJ, Wilkins KJ, Alakwaa F, Liu F, Torre-Healy LA, Krichevsky S, Hong SS, Sakhuja A, Potu CK, Saltz JH, Saran R, Zhu RL, Setoguchi S, Kane-Gill SL, Mallipattu SK, He Y, Ellison DH, Byrd JB, Parikh CR, Moffitt RA, Koraishy FM; N3C and RECOVER Consortia.Clin J Am Soc Nephrol. 2023 Aug 1;18(8):1006-1018. doi: 10.2215/CJN.0000000000000192. Epub 2023 Jun 5.PMID: 37131278
  5. Single-Cell Spatial MIST for Versatile, Scalable Detection of Protein Markers. Meah A, Vedarethinam V, Bronstein R, Gujarati N, Jain T, Mallipattu SK, Li Y, Wang J.Biosensors (Basel). 2023 Aug 27;13(9):852. doi: 10.3390/bios13090852.PMID: 37754086 Free PMC article.
  6. Bayesian methods: a potential path forward for sepsis trials.Tomlinson G, Al-Khafaji A, Conrad SA, Factora FNF, Foster DM, Galphin C, Gunnerson KJ, Khan S, Kohli-Seth R, McCarthy P, Meena NK, Pearl RG, Rachoin JS, Rains R, Seneff M, Tidswell M, Walker PM, Kellum JA.Crit Care. 2023 Nov 8;27(1):432. doi: 10.1186/s13054-023-04717-x.PMID: 37940985 Free PMC article.
  7. Endotoxemia Correlates with Kidney Function and Length of Stay in Critically Ill Patients. Piret SE, Khan S, Fairuz F, Gholami S, Davis M, Kim CK, Espinoza M, Foster D, Kellum JA, Ahmad S, Kalogeropoulos AP, Mallipattu SK.Blood Purif. 2023 Nov 2:1-10. doi: 10.1159/000534107. Online ahead of print.PMID: 37918364
  8. Ablation of Long Noncoding RNA Hoxb3os Exacerbates Cystogenesis in Mouse Polycystic Kidney Disease. Weisser I, Eckberg K, D'Amico S, Buttram D, Aboudehen K.J Am Soc Nephrol. 2023 Nov 13. doi: 10.1681/ASN.0000000000000265. Online ahead of print.PMID: 37953472
  9. Increased renal elimination of endogenous and synthetic pyrimidine nucleosides in concentrative nucleoside transporter 1 deficient mice. Persaud AK, Bernier MC, Massey MA, Agrawal S, Kaur T, Nayak D, Xie Z, Weadick B, Raj R, Hill K, Abbott N, Joshi A, Anabtawi N, Bryant C, Somogyi A, Cruz-Monserrate Z, Amari F, Coppola V, Sparreboom A, Baker SD, Unadkat JD, Phelps MA, Govindarajan R.Nat Commun. 2023 Jun 1;14(1):3175. doi: 10.1038/s41467-023-38789-8.PMID: 37264059 Free PMC article.
  10. Inhibition of the glucocorticoid receptor attenuates proteinuric kidney diseases in multiple species. Stamellou E, Agrawal S, Siegerist F, Buse M, Kuppe C, Lange T, Buhl EM, Alam J, Strieder T, Boor P, Ostendorf T, Gröne HJ, Floege J, Smoyer WE, Endlich N, Moeller MJ.Nephrol Dial Transplant. 2023 Nov 30:gfad254. doi: 10.1093/ndt/gfad254. Online ahead of print.PMID: 38037533
  11. Glucocorticoid- and Pioglitazone-Induced Proteinuria Reduction in Experimental Nephrotic Syndrome Both Correlate with Glomerular ECM Modulation Sagar Bhayan, Julie A. Dougherty, Yu Kamigaki, Shipra Agrawal, Saranga Wijeratne, James Fitch, Amanda P. Waller, Katelyn J. Wolfgang, Peter White, Bryce A. Kerlin, William E. Smoyer

American Society of Nephrology (ASN) 2023 Presentations (November 2023)

Publications in 2022:

  1. Gras-Peña R, Danzl NM, Khosravi-Maharlooei M, Campbell SR, Ruiz AE, Parks CA, Suen Savage WM, Holzl MA, Chatterjee D, Sykes M. Human stem cell-derived thymic epithelial cells enhance human T-cell development in a xenogeneic thymus. J Allergy Clin Immunol. 2022 May;149(5):1755-1771.
  2. Nauman G, Danzl NM, Lee J, Borsotti C, Madley R, Fu J, Hölzl MA, Dahmani A, Dorronsoro Gonzalez A, Chavez É, Campbell SR, Yang S, Satwani P, Liu K, Sykes M. Defects in Long-Term APC Repopulation Ability of Adult Human Bone Marrow Hematopoietic Stem Cells (HSCs) Compared with Fetal Liver HSCs. J Immunol. 2022 Apr 1;208(7):1652-1663.
  3. COVID-19-associated AKI in hospitalized US patients: incidence, temporal trends, geographical distribution, risk factors and mortality. Masthead; Yoo YJ, Wilkins KJ, Alakwaa F, Liu F, Torre-Healy LA, Krichevsky S, Hong SS, Sakhuja A, Potu CK, Saltz JH, Saran R, Zhu RL, Setoguchi S, Kane-Gill SL, Mallipattu SK, He Y, Ellison DH, Byrd JB, Parikh CR, Moffitt RA, Koraishy FM. medRxiv. 2022 Sep 2:2022.09.02.22279398. doi: 10.1101/2022.09.02.22279398. Preprint. PMID: 36093355 Free PMC article.
  4. Endothelial-specific loss of Krüppel-Like Factor 4 triggers complement-mediated endothelial injury. Estrada CC, Cardona S, Guo Y, Revelo MP, D'Agati VD, Koganti S, Devaraj J, He JC, Heeger PS, Mallipattu SK. Kidney Int. 2022 Jul;102(1):58-77. doi: 10.1016/j.kint.2022.03.025. Epub 2022 Apr 26. PMID: 35483525
  5. Diabetes medications and associations with Covid-19 outcomes in the N3C database: A national retrospective cohort study. Bramante CT, Johnson SG, Garcia V, Evans MD, Harper J, Wilkins KJ, Huling JD, Mehta H, Alexander C, Tronieri J, Hong S, Kahkoska A, Alamgir J, Koraishy F, Hartman K, Yang K, Abrahamsen T, Stürmer T, Buse JB; N3C core authors. PLoS One. 2022 Nov 17;17(11):e0271574. doi: 10.1371/journal.pone.0271574. eCollection 2022. PMID: 36395143 Free PMC article.
  6. Polygenic association of glomerular filtration rate decline in world trade center responders. Koraishy FM, Mann FD, Waszczuk MA, Kuan PF, Jonas K, Yang X, Docherty A, Shabalin A, Clouston S, Kotov R, Luft B. BMC Nephrol. 2022 Oct 28;23(1):347. doi: 10.1186/s12882-022-02967-5. PMID: 36307804 Free PMC article.
  7. Alternatively Spliced Landscape of PPARγ mRNA in Podocytes Is Distinct from Adipose Tissue.Bryant C, Webb A, Banks AS, Chandler D, Govindarajan R, Agrawal S. Cells. 2022 Nov 1;11(21):3455. doi: 10.3390/cells11213455. PMID: 36359851 Free PMC article.
  8. Adriamycin-Induced Nephropathy is Robust in N and Modest in J Substrain of C57BL/6. Bryant C, Cianciolo R, Govindarajan R, Agrawal S. Front Cell Dev Biol. 2022 Jun 16;10:924751. doi: 10.3389/fcell.2022.924751. eCollection 2022. PMID: 35784478 Free PMC article.
  9. Selective modulator of nuclear receptor PPARγ with reduced adipogenic potential ameliorates experimental nephrotic syndrome. Bryant C, Rask G, Waller AP, Webb A, Galdino-Pitta MR, Amato AA, Cianciolo R, Govindarajan R, Becknell B, Kerlin BA, Neves FAR, Fornoni A, Agrawal S. iScience. 2022 Feb 28;25(4):104001. doi: 10.1016/j.isci.2022.104001. eCollection 2022 Apr 15. PMID: 35310946 Free PMC article.
  10. Multiomics analysis reveals that hepatocyte nuclear factor 1β regulates axon guidance genes in the developing mouse kidney. Shao A, Gearhart MD, Chan SC, Miao Z, Susztak K, Igarashi P Sci Rep. 2022 Oct 20;12(1):17586. doi: 10.1038/s41598-022-22327-5 PMID: 36266461
  11. Small hairpin inhibitory RNA delivery in the metanephric organ culture identifies long noncoding RNA Pvt1 as a modulator of cyst growth. Eckberg K, Weisser I, Buttram D, Somia N, Igarashi P, Aboudehen KS.Am J Physiol Renal Physiol. 2022 Sep 1;323(3):F335-F348. doi: 10.1152/ajprenal.00016.2022. Epub 2022 Jul 21.PMID: 35862648 Free PMC article.

American Society of Nephrology (ASN) 2022 Presentations (November 2022)

Publications in 2021:

  1. Piret SE*, Attallah AA*, Gu X, Guo Y, Gujarati NA, Henein J, Zollman A, Hato T, Ma’ayan A, Revelo MP, Dickman KG, Chen CH, Shun CT, Rosenquist TA, He JC, Mallipattu SK. Loss of proximal tubular Krüppel-like factor 15 (KLF15) exacerbates kidney injury through loss of fatty acid oxidation. Kidney International (2021) 100: 1250-67. *joint first authors.
  2. Piret SE, Guo Y, Attallah AA, Horne SJ, Zollman A, Owusu D, Henein J, Sidorenko VS, Revelo MP, Hato T, Ma’ayan A, He JC, Mallipattu SK. Krüppel-like factor 6-mediated loss of BCAA catabolism contributes to kidney injury in mice and humans. PNAS (2021) 118: e2024414118.
  3. "Monitoring Hospitalized dialysis patients with COVID-19: repurposing baby monitors for patient and staff safety." Kidney Med. 2021 Jan-Feb;3(1):136-138. doi: 10.1016/j.xkme.2020.10.004. Epub 2020 Dec 10. 
  4. Endotoxemia in Critically ill patients with COVID-19.” https://www.karger.com/Article/FullText/518230#. Sobia Khan, Olena Bolotova, Haseena Sahib, Debra Foster, Sandeep Mallipattu
  5. Short- and Long-Term Recovery after Moderate/Severe AKI in Patients with and without COVID-19. Sun S, Annadi RR, Chaudhri I, Munir K, Hajagos J, Saltz J, Hoai M, Mallipattu SK, Moffitt R, Koraishy FM. Kidney360. 2021 Nov 29;3(2):242-257. doi: 10.34067/KID.0005342021. eCollection 2022 Feb 24. PMID: 35373118 Free PMC article.
  6. Podocyte-specific KLF4 is required to maintain parietal epithelial cell quiescence in the kidney. Pace JA, Bronstein R, Guo Y, Yang Y, Estrada CC, Gujarati N, Salant DJ, Haley J, Bialkowska AB, Yang VW, He JC, Mallipattu SK. Sci Adv. 2021 Sep 3;7(36):eabg6600. doi:10.1126/sciadv.abg6600. Epub 2021 Sep 3. PMID: 34516901 Free PMC article.
  7.  Characterizing Long COVID: Deep Phenotype of a Complex Condition. Deer RR, Rock MA, Vasilevsky N, Carmody L, Rando H, Anzalone AJ, Basson MD, Bennett TD, Bergquist T, Boudreau EA, Bramante CT, Byrd JB, Callahan TJ, Chan LE, Chu H, Chute CG, Coleman BD, Davis HE, Gagnier J, Greene CS, Hillegass WB, Kavuluru R, Kimble WD, Koraishy FM, Köhler S, Liang C, Liu F, Liu H, Madhira V, Madlock-Brown CR, Matentzoglu N, Mazzotti DR, McMurry JA, McNair DS, Moffitt RA, Monteith TS, Parker AM, Perry MA, Pfaff E, Reese JT, Saltz J, Schuff RA, Solomonides AE, Solway J, Spratt H, Stein GS, Sule AA, Topaloglu U, Vavougios GD, Wang L, Haendel MA, Robinson PN. EBioMedicine. 2021 Dec;74:103722. doi: 10.1016/j.ebiom.2021.103722. Epub 2021 Nov 25. PMID: 34839263 Free PMC article. Review.
  8. The Association of Posttraumatic Stress Disorder With Longitudinal Change in Glomerular Filtration Rate in World Trade Center Responders. Koraishy FM, Coca SG, Cohen BE, Scherrer JF, Mann F, Kuan PF, Luft BJ, Clouston SAP. Psychosom Med. 2021 Nov-Dec 01;83(9):978-986. doi: 10.1097/PSY.0000000000000968. PMID: 34297009 Free PMC article.
  9. Challenges in defining Long COVID: Striking differences across literature, Electronic Health Records, and patient-reported information.Rando HM, Bennett TD, Byrd JB, Bramante C, Callahan TJ, Chute CG, Davis HE, Deer R, Gagnier J, Koraishy FM, Liu F, McMurry JA, Moffitt RA, Pfaff ER, Reese JT, Relevo R, Robinson PN, Saltz JH, Solomonides A, Sule A, Topaloglu U, Haendel MA. medRxiv. 2021 Mar 26:2021.03.20.21253896. doi: 10.1101/2021.03.20.21253896. Preprint. PMID: 33791733 Free PMC article.
  10. Sun S, Annadi RR, Chaudhri I, Munir K, Hajagos J, Saltz J, Hoai M, Mallipattu SK, Moffitt R, Koraishy FM. Short- and Long-Term Recovery after Moderate/Severe AKI in Patients with and without COVID-19. Kidney360. 2021 Nov 29;3(2):242-257. doi: 10.34067/KID.0005342021. eCollection 2022 Feb 24.
  11. Deer RR, Rock MA, Vasilevsky N, Carmody L, Rando H, Anzalone AJ, Basson MD, Bennett TD, Bergquist T, Boudreau EA, Bramante CT, Byrd JB, Callahan TJ, Chan LE, Chu H, Chute CG, Coleman BD, Davis HE, Gagnier J, Greene CS, Hillegass WB, Kavuluru R, Kimble WD, Koraishy FM, Köhler S, Liang C, Liu F, Liu H, Madhira V, Madlock-Brown CR, Matentzoglu N, Mazzotti DR, McMurry JA, McNair DS, Moffitt RA, Monteith TS, Parker AM, Perry MA, Pfaff E, Reese JT, Saltz J, Schuff RA, Solomonides AE, Solway J, Spratt H, Stein GS, Sule AA, Topaloglu U, Vavougios GD, Wang L, Haendel MA, Robinson PN. Characterizing Long COVID: Deep Phenotype of a Complex Condition. EBioMedicine. 2021 Dec;74:103722. doi: 10.1016/j.ebiom.2021.103722. Epub 2021 Nov 25.
  12. Koraishy FM, Coca SG, Cohen BE, Scherrer JF, Mann F, Kuan PF, Luft BJ, Clouston S. The Association of Post-Traumatic Stress Disorder with longitudinal change in Glomerular Filtration Rate in World Trade Center responders. Psychosom Med. 2021 Jul 7. doi: 10.1097/PSY.0000000000000968. Online ahead of print.
  13. Bennett TD, Moffitt RA, Hajagos JG, Amor B, Anand A, Bissell MM, Bradwell KR, Bremer C, Byrd JB, Denham A, DeWitt PE, Gabriel D, Garibaldi BT, Girvin AT, Guinney J, Hill EL, Hong SS, Jimenez H, Kavuluru R, Kostka K, Lehmann HP, Levitt E, Mallipattu SK, Manna A, McMurry JA, Morris M, Muschelli J, Neumann AJ, Palchuk MB, Pfaff ER, Qian Z, Qureshi N, Russell S, Spratt H, Walden A, Williams AE, Wooldridge JT, Yoo YJ, Zhang XT, Zhu RL, Austin CP, Saltz JH, Gersing KR, Haendel MA, Chute CG; National COVID Cohort Collaborative (N3C) Consortium. Clinical Characterization and Prediction of Clinical Severity of SARS-CoV-2 Infection Among US Adults Using Data From the US National COVID Cohort Collaborative. JAMA Netw Open. 2021 Jul 1;4(7):e2116901. doi: 10.1001/jamanetworkopen.2021.16901.
  14. Rando HM, Bennett TD, Byrd JB, Bramante C, Callahan TJ, Chute CG, Davis HE, Deer R, Gagnier J, Koraishy FM, Liu F, McMurry JA, Moffitt RA, Pfaff ER, Reese JT, Relevo R, Robinson PN, Saltz JH, Solomonides A, Sule A, Topaloglu U, Haendel MA. Challenges in defining Long COVID: Striking differences across literature, Electronic Health Records, and patient-reported information. medRxiv. 2021 Mar 26:2021.03.20.21253896. doi: 10.1101/2021.03.20.21253896. Preprint.
  15. Agrawal S*, He JC, Tharaux PL. Nuclear receptors in podocyte biology and glomerular disease. Nat Rev Nephrol. 2021 Mar;17(3):185-204. doi: 10.1038/s41581-020-00339-6. Review. PMID: 32943753. *Corresponding author

Presentations in 2021:

Abstracts: 

  • Unusual Pathogen Causing Peritonitis in a Peritoneal Dialysis (PD) Patient, PUB123, Rula Abdulrahman
  • A case of renal amyloidosis (AD) presented as orthostatic hypotension" accepted for publication in ASN's 2022 Abstract Supplement, which will be available via the ASN, Rula Abdulrahman
  • Recreation with a Concerning diagnosis (ASN 2021) Sobia Khan, Heesukh Suh
  • Association of Endotoxemia with AKI in critically ill patients with SARS-CoV-2 infection (ASN 2021) Sobia Khan, Olena Bolotova, Chris R. Gordon, Sandeep Mallipattu
  • Circulating Endotoxin levels correlate with kidney and mortality outcomes in critically ill patients (ASN 2021) Chang Kyung Kim, Sobia Khan, Fabliha Fairuz, Sandeep Mallipattu, Sian Piret (ASN 2021) 
  • An unusual complication of IgG4-related interstitial nephritis as Resistant HTN" (ASN 2022). Hubert Wang MD, Monica P. Revelo MD, Sobia Khan DO
  • Use of Polymyxin (PMX) B cartridge in a patient with Acute kidney injury (AKI) and Septic shock" Accepted to be published in ASN's 2022 Abstract Supplement. Sobia Khan DO and Sandeep Mallipattu MD

Publications in 2020:

American Society of Nephrology (ASN) 2020 Presentations:
October 2020

  • Prospective feasibility study with the use of losartan in COVID-19 (Dr. Olena Bolotova, Dr. Sandeep Mallipattu, Dr. Farrukh Koraishy, Ms. Haseena Sahib)
  • Association between kidney dysfunction at admission and outcomes in hospitalized patients with COVID-19 (Dr. Olena Bolotova, Dr. Sandeep Mallipattu, Dr. Farrukh Koraishy)
  • Podocyte-Specific Induction of KLF6 Attenuates Diabetic Kidney Disease in Mice (Dr. Nehaben Gujarati, Dr. Sandeep Mallipattu)
  • Rare case of MPO-ANCA positive Polyarteritis Nodosa (Dr. Bhaktidevi Makadia, Dr. Sandeep Mallipattu)
  • Outcomes associated with the use of Angiotensin Converting Enzyme Inhibitors and Angiotensin II Receptor Blockers in hospitalized patients with SARS-CoV-2 infection (Dr. Olena Bolotova, Dr. Sandeep Mallipattu, Dr. Farrukh Koraishy, Ms. Haseena Sahib)
  • An Unusual Case of Complement Mediated TMA (Dr. Sobia Khan, Dr. Wilfred Lieberthal) 

Accepted to be published in ASN's 2020 Abstract Supplement:

  • Starvation Induced Metabolic Acidosis in a COVID-19 Infected Pregnant Patient (Dr. Muhammad Mustafa)|
  • Repurposing Baby Monitors in COVID-19 (Dr. Sobia Khan and Dr. Sandeep Mallipattu)
  • AKI with Minimal Pulmonary Pathology in SARS-CoV2 Infection (Dr. Frank Yasnowski and Dr. Rajeev Rohatgi)
  • Optimizing On-the-Go Learning Utilizing Short Modules on Topics Related to Nephrology (Dr. Kiran Munir and Dr. Farah Daccueil)


American Society of Nephrology (ASN) 2020 Oral Presentations (Simulive & On Demand):

  • Elucidating Pathophysiology of Acute Kidney Injury, October 24, 2020 (On Demand, Dr. Sian Piret)
  • Tubular Maladaptive Responses After Injury: New Paradigm in Kidney Fibrosis, Including the Barry M. Brenner, MD, Endowed Lectureship, October 22, 2020 (Simulive 10:30 am-12:30 pm, Dr. Sandeep Mallipattu; Moderator)
  • Kruppel-Like Factors and DKD, October 24, 2020 (On Demand, Dr. Sandeep Mallipattu)
  • Loss of Functional SCO2 Attenuates Diabetic Kidney Disease in db/db Mice, October 24, 2020 (Simulive 5pm-7pm, Dr. Nehaben Gujarati)

Publications in 2019:


ASN Kidney Week 2019 Abstracts Accepted by the American Society of Nephrology
November 2019

  • Denosumab Induced Severe Hypocalcemia and Hyperparathyroidism in a Peritoneal Dialysis Patient (Dr. Akintunde Akinjero)
  • Role of AMPK and KLF4 in Determining the Survival of Cisplatin-Treated Human Umbilical Vein Endothelial Cells (Dr. Wilfred Lieberthal and Dr. Sandeep Mallipattu)
  • Identification of podocyte secreted proteins that drive parietal epithelial cell proliferation in a murine model of proliferative glomerulopathy (Jesse Pace) 
  • Proximal tubule-specific KLF6 mediated amino acid metabolism is critical for the progression of kidney injury (Dr. Sian Piret)
  • Impact of In-House Dialysis Schedule Change on Hospital Readmission Rate in Hemodialysis Patients (Dr. Abdul Qadeer)
  • Human Podocyte Modifies Energy Metabolism during Differentiation (Dr. Jessica Vasquez)
  • Chronic Fluid Shear Stress (FSS) Induces ERK Dependent Sodium Transport in Principal Cells (PCs) (Dr. Robert Lawrence, Dr. Rajeev Rohatgi and more)
  • Loss of Endothelial Klf4 leads to severe glomerular endothelial injury in aged mice (Dr. Chelsea Estrada, Stephanie Cardona, Dr. Sandeep Mallipattu, Dr. Monica Penafiel)
  • Health-Related Quality of Life Among Kidney Transplant Patients Using the PROMIS Global Health Scale (Dr. Farrukh Koraishy)
  • Use of Opioids and Nonsteroidal Anti-Inflammatory Drugs in Living Kidney Donors: Clinical Correlates and Early Outcomes (Dr. Farrukh Koraishy)
  • Epidemiology of Pericardial Effusions in Patients with End-Stage Renal Disease on Hemodialysis (Dr. Leyla Gasimli-Gamache, Dr. Shilpa Vijayakumar, Dr. Sahar Ahmad, Dr. Sandeep Mallipattu)

Presented at the American Society of Nephrology (ASN) Kidney Week: Glomerular and Tubular Origins of Albuminuria
(Dr. Sandeep Mallipattu)

Publications in 2018:

  • Kathleen Dickman, PhD and her team developed a new, non-invasive urine-based test to detect urothelial cancers of the bladder and upper urinary tract with high sensitivity and selectivity. 
  • Telenephrology: Providing Healthcare to Remotely Located Patients with Chronic Kidney Disease (Dr. Rajeev Rohatgi and team at Northport Veterans Affairs Medical Center)