Andrea Arreguin 
Education:
B.A. Biology with a specialization in neurobiology, Boston University (2014)
Current Position:
7th Year MSTP
3rd Year Medical Student
Advisor:
Holly Colognato, PhD
Graduate Program:
Neuroscience
Research Interest:
I am interested in understanding the role of stem cells in the adolescent and adult brain. I joined the lab of Dr. Holly Colognato to study neural stem cells and the extracellular matrix, which I hope to use to answer essential questions about the development of the nervous system. I will be exploring the roles of the dystrophin-glycoprotein complex and other extracellular matrix proteins in the postnatal subventricular zone neural stem cell niche.
In my free time, I enjoy running, cooking, traveling, and watching/playing sports. I am an avid tennis and soccer fan.
Awards:
W. Burghardt Turner Fellowship 2016-Present
SUNY Graduate Research Empowering and Accelerating Talent Award, 2022
Turner Summer Research Grant 2020, 2022
Excellence in Promoting Diversity and Inclusion Award, MSTP Retreat 2021
Hispanic Heritage Month Leadership Award 2018
SOM International Travel Alumni Award 2017
Black Faculty and Staff Association Scholarship 2017
Publications:
(MSTP-supported publications indicated with an *)
Arreguin AJ*, Colognato H. “Brain dysfunction in LAMA2-related Congenital Muscular Dystrophy: lessons from human case reports and mouse models” Frontiers in Molecular Neuroscience. 13 (2020):18.
Negro A, Seidel J, Houben T, Yu E, Rosen I, Arreguin AJ, Yalcin N, Shorser-Gentile L, Pearlman L, Sadhegian HL, Chamberlin NL, Ayata C, Martelletti P, Moskowitz MA, Eikermann-Haerter K. Sleep deprivation enhances susceptibility to the migraine substrate cortical spreading depolarization. The Journal of Headache and Pain. 21.1 (2020): 1-11.
Palomo GM, Granatiero V, Kawamata H, Konrad C, Kim M, Arreguin AJ, Zhao D, Milner TA, Manfredi G. Parkin is a disease modifier in the mutant SOD1 mouse model of ALS. EMBO molecular medicine. 2018 Oct 1;10(10).
Chen Q, Kirk K, Shurubor YI, Zhao D, Arreguin AJ, Shahi I, Valsecchi F, Primiano G, et al. Rewiring of glutamine metabolism is a bioenergetic adaptation of human cells with mitochondrial DNA mutations. Cell metabolism. 2018 May 1;27(5):1007-25.
Konrad C, Kawamata H, Bredvik KG, Arreguin AJ, Cajamarca SA, Hupf JC, et al. Fibroblast bioenergetics to classify amyotrophic lateral sclerosis patients. Molecular Neurodegeneration. 2017;12(1):76.
Riar AK, Burstein SR, Palomo GM, Arreguin A, Manfredi G, Germain D. Sex specific activation of the ERalpha axis of the mitochondrial UPR (UPRmt) in the G93A-SOD1 mouse model of familial ALS. Human Molecular Genetics. 2017;26(7):1318-27.
Eikermann-Haerter, K., Arbel-Ornath, M., Yalcin, N., Yu, E. S., Kuchibhotla, K. V., Yuzawa, I., Hudry, E., Willard, C. R., Climov, M., Keles, F., Belcher, A. M., Sengul, B., Negro, A., Rosen, I. A., Arreguin, A., et al. Abnormal synaptic Ca(2+) homeostasis and morphology in cortical neurons of familial hemiplegic migraine type 1 mutant mice. Annals of Neurology. 2015;78(2):193-210.
Park, L., Zhou, J., Zhou, P., Pistick, R., El Jamal, S., Younkin, L. Pierce, J., Arreguin, A., et al. Innate immunity receptor CD36 promotes cerebral amyloid angiopathy. PNAS 2013;110:3089-94.
