Gabriel Chan
Education:
B.A. Columbia University (2023)
Masters École Normale Supérieure Paris-Saclay (2024)
Current Position:
1st Year MSTP
1st Year Medical Student
Advisor:
TBA
Graduate Program:
TBA
Research Interests:
My undergraduate research work focused on understanding the dynamics of neural activity in the prefrontal cortex under the supervision of Dr. Yanliang Shi and Dr. Tatiana Engel. I also conducted immunotherapy research under the supervision of Dr. Pawel Muranski, focusing on constructing HHV8-virus-specific T-cells.
During my gap year, I was a visiting student in the École Normale Supérieure Paris-Saclay on a Fulbright Research Fellowship. At Dr. Jean-Luc Martinot’s lab, I identified novel structural predictors of resilience in children and adolescents by applying machine learning tools to analyze neuro-imaging and socio-economic data from over 11,000 US children and adolescents.
The goal of my graduate study is to apply these various research experiences to the study of cancer, specifically in the field of cancer neuroscience. The complex dynamics of biological systems cannot be captured by interrogating single genes/cells but require the exploration and examination of networks of interactions within and across cells. I want to develop mathematical and computational models to study the influence of the nervous system on cancer at the systems level, so as to infer potential therapeutic targets, which will then be tested employing in vitro and in vivo model systems.
Publications:
Acute Management of Seizure Clusters and Prolonged Seizures: A Review of Rescue Therapies
Sadie Goodman∗, Gabriel Chan∗, Nisali A Gunawardane, & Ruben I Kuzniecky, touchREVIEWS in Neurology. 2024;20(1): Online ahead of journal publication
∗Joint First author.
Identification of Master Regulator Genes of UV Response and Their Implications for Skin Carcinogenesis
Yao Shen, Gabriel Chan, Michael Xie, Wangyong Zeng & Liang Liu, Carcinogenesis, 40(5):687-694 (2019)
Conference Posters/Presentations:
Chan, G., Martinot, J.L., Paillère, M.L., & Artiges, E.
Resilience to Adversity and White-Matter Microstructure in Adolescence: A Replication Study in the ABCD Cohort, March 2024, Poster Presentation given at ABCD Insights & Innovations Meeting (AIIM), by Gabriel Chan, Washington, D.C.
Chan, G., Shi, Y., Chen, X., Moore, T., & Engel, T.A.
Cortical State Dynamics in the Frontal Eye Field (FEF) during Spontaneous Activity, November 2023, Poster Presentation given at Society for Neuroscience (SfN), Neuroscience 2023 by Gabriel Chan, Washington, D.C.
