Gabriel Chan
Education:
B.A. Columbia University (2023)
Masters École Normale Supérieure Paris-Saclay (2024)
Advisor:
Lucas Cheadle
Graduate Program:
Genetics
Research Interests:
My undergraduate research work focused on understanding the dynamics of neural activity in the prefrontal cortex under the supervision of Dr. Yanliang Shi and Dr. Tatiana Engel. I also conducted immunotherapy research under the supervision of Dr. Pawel Muranski, focusing on constructing HHV8-virus-specific T-cells.
During my gap year, I was a visiting student in the École Normale Supérieure Paris-Saclay on a Fulbright Research Fellowship. At Dr. Jean-Luc Martinot’s lab, I identified novel structural predictors of resilience in children and adolescents by applying machine learning tools to analyze neuro-imaging and socio-economic data from over 11,000 US children and adolescents.
The goal of my graduate study is to apply these various research experiences to the study of cancer, specifically in the field of cancer neuroscience. I apply mathematical and computational models to interrogate neuroimmune interactions in glioblastoma, and then validate and extend these findings using advanced imaging techniques. With direct collaboration with neurosurgeons, we aims to ensure that our findings in the lab are directly translatable to the clinic.
Publications:
Early Adolescence Brain Structure Features Implicated in Resilience to Development of Behavioral and Emotional Problems After Exposure to Adversity
Gabriel Chan, Julia Ruiz-Fernandez, Marie-Laure Paillère Martinot, Ioannis Bargiotas, Nicolas Vayatis, Eric Artiges, and Jean-Luc Martinot, under review at Translational Psychiatry (2026).
Spatiotemporal Dynamics of Cortical States in Prefrontal Cortex
Yan-Liang Shi, Gabriel Chan, Xiaomo Chen, Tirin Moore, Kwabena Boahen and Tatiana Engel, to appear in bioRxiv (2026).
A Single-Center Study of Insurance as a Socioeconomic Determinant of Severe Traumatic Brain Injury Outcomes
Noah Lubin, Justin Passman, Alfonse Mazzarella, Emily Bellow, Gabriel Chan, Heshwin Singh, Jason Zhang, Jermaine Robertson, Gabriela Ostrowski, Charles Mikell, and Sima Mofakham, Accepted at Neurotrauma Reports (2026).
Exploring the Potential of Psychedelics in the Treatment of Headache Disorders: Clinical Considerations and Exploratory Insights
Isabella Henderson * , Ronnie Elsaadany * , Gabriel Chan * , Vikram Bajaj, Diana Duarte, Sadie Goodman, Michael Grunstein, Nehal P. Vadhan & Robert A. Duarte. Current Pain and Headache Reports 29, 28 (2025).
*Joint first author.
Acute Management of Seizure Clusters and Prolonged Seizures: A Review of Rescue Therapies
Sadie Goodman * , Gabriel Chan * , Nisali A Gunawardane, & Ruben I Kuzniecky, touchREVIEWS in Neurology. 2024;20(1): Online ahead of journal publication.
*Joint first author.
Identification of Master Regulator Genes of UV Response and Their Implications for Skin Carcinogenesis
Yao Shen, Gabriel Chan, Michael Xie, Wangyong Zeng & Liang Liu, Carcinogenesis, 40(5): 687-694 (2019).
Conference Posters/Presentations:
Bayan Razzaq, Susan Fiore, Mohsen Ahmed, Justin Passman, Chan, G., Frederick Gutman, and David Chesler
A Rare Glimpse into the 17-Year Evolution of an Untreated IDH-Mutant Astrocytoma, November 2024, Abstract submitted and accepted for Poster Presentation to the Society for Neuro-Oncology's 2024 Annual Meeting, by Bayan Razzaq
Chan, G., Susan Fiore, Bayan Razzaq, Justin Passman, Peter Gerace, Scott Sun, Helen Hsieh, and David Chesler
Imaging-Based Distinction of IDH-Mutant and IDH–Wildtype WHO Grade 4 Gliomas: A Pilot Analysis, August 2025, Abstract submitted and accepted for Poster Presentation to the Congress of Neurological Surgeons' 2025 Annual Meeting, by Gabriel Chan
Chan, G., Julia-Ruiz Fernandez, Marie-Laure Paillère, Ioannis Bargiotas, Nicolas Vayatis, Eric Artiges & Jean-Luc Martinot
Machine Learning Prediction of Resilience in the ABCD Dataset - Preliminary Data and Future Questions, May 2025, Symposium Talk given at INSERM Mathématiques & Médecine, Addictions : Intérêt des Modèles Développementaux, by Gabriel Chan, Gif-sur-Yvette
Chan, G., Julia-Ruiz Fernandez, Marie-Laure Paillère, Ioannis Bargiotas, Nicolas Vayatis, Eric Artiges & Jean-Luc Martinot
Resilience and Adolescent Brain Structure Protective Features: A Confirmation and Machine Learning Study, April 2025, Abstract submitted and accepted for Poster Presentation to the Society of Biological Psychiatry's 2025 Annual Meeting, by Gabriel Chan, Toronto
Chan, G., Martinot, J.L., Paillère, M.L., & Artiges, E.
Resilience and White-Matter Microstructure in Adolescence: A Replication Study in the ABCD Cohort, December 2023, Abstract submitted and accepted for Poster Presentation to ABCD Insights & Innovations Meeting (AIIM), by Gabriel Chan, Washington, D.C.
Chan, G., Shi, Y., Chen, X., Moore, T., & Engel, T.A.
Cortical State Dynamics in the Frontal Eye Field (FEF) during Spontaneous Activity, November 2023, Abstract submitted and accepted for Poster Presentation to Society for Neuroscience (SfN), Neuroscience 2023 by Gabriel Chan, Washington, D.C.