Education:
B.A. Biochemistry - Case Western Reserve University, Cleveland, OH (2015)
Current Position:
8th Year MSTP
4th Year Medical Student
Advisor:
Richard Moffitt, PhD
Graduate Program:
Biomedical Informatics
Research Interest:
I am interested in the development and implementation of personalized medicine into our modern healthcare system. With newer tools in multi-omics and artificial intelligence, I believe personalized medicine will continue to shape how we practice medicine (prevention, diagnosis, prognosis, and targeted therapies). In past labs, I have studied novel enzyme kinetics, structures of retinoid transporters in the eye, microtubule dynamics, single-cell genomics, and microfluidics. During my PhD, my primary focus involved studying how cell compartments within the tumor microenvironment (fibroblasts, lymphocytes, macrophages, and tumor cells) vary in pancreatic cancer patients. Our work emphasized the importance of appreciating the molecular diversity among cancer patients and provides a roadmap to personalized therapies based on distinct phenotypic patterns within the TME.
Publications:
Oh K, et al. Nature Communications “Coordinated Single Cell Tumor Microenvironment Dynamics Reinforce Pancreatic Cancer Subtype” (Accepted 2023).
Achonu J, Oh K, et al. “Epidemiologic patterns of adolescent idiopathic scoliosis detection and treatment in New York state” Journal of Pediatric Orthopaedics (2023) e001066.
Torre-Healy L, Kawalerski R, Oh K, et al. “Open-source curation of a pancreatic ductal adenocarcinoma gene expression analysis platform supports a two-subtype model” Communications Biology (2023) 6(1):163
Caponegro M, Oh K, et al. “A distinct microglial subset at the tumor–stroma interface of glioma” Glia (2021), 69(7)1767-1781
Caponegro M, Oh K, Sterge N, Moffitt R, Tsirka S. A Microglial Subset at the Tumor‐Stroma Border in High Grade Glioma. The FASEB Journal (2020) 34 (S1), 1-1
Rao M, Oh K, Moffitt R, Thompson P, Li P, Liu J, Sasson A, Georgakis G, et al. Comparative single-cell RNA sequencing (scRNA-seq) reveals liver metastasis–specific targets in a patient with small intestinal neuroendocrine cancer. Molecular Case Studies (2020) 6 (2), a004978
Yu J, Oh K, et al. “Enzymatic-based cytometry, a sensitive single-cell cytometric method to assess BCR-ABL1 activity in CML” Lab on a Chip (2020) 20(5):942-948.
Chen Y, Tang H, Seibel W, Oh, K., et al. “Identification and characterization of novel inhibitors of Mammalian aspartyl aminopeptidase” Mol Pharmacol. (2014);86(2):231-42.
Conference Posters/Presentations:
Oh K, Torre-Healy L, et al. Coordinated Single Cell Tumor Microenvironment Dynamics Reinforce Pancreatic Cancer Subtype – Dep. Heme/Onc GI Meeting Emory University (Atlanta, GA 2023)
Yoo YJ, Oh K, et al. Meta-analysis of single-cell RNA expression in genetically engineered mouse models of pancreatic ductal adenocarcinoma reveals inter-model heterogeneity – American Association for Cancer Research (AACR) Pancreatic Cancer (Boston, MA 2022)
Gruttadauria M, Oh K, et al. Implementation of Video Education Improves Patient Satisfaction in Colposcopy - American College of Obstetrics and Gynecology (ACOG 2021)
Liu Y, Kim S, Roselaar N, Oak C, Oh, K, et al. “A Retrospective Cohort Study on the Effects of Postoperative Phone Calls after Benign Gynecologic Surgery”. American Association of Gynecologic Laparoscopists (AAGL 2021)
Caponegro M, Oh K, et al. Microglial Subset at the Tumor-Stroma Border in High Grade Glioma barrier (AACR San Diego, CA – 2020)
Oh K, Rao M, et al. “Defining heterogeneity of molecular subtypes within the Microenvironment of Pancreatic Ductal Adenocarcinoma by Single-Cell RNA-Seq” (AACR Pancreatic Cancer Boston, MA – 2019)
o 34th National MD/PhD Conference Copper Mountain, CO - 2019
o Gloria & Mark Snyder Cancer Research Symposium – 2019
o Stony Brook Cancer Center Research Symposium – 2019
Rout R, Oh K, et al. “Exploring Gene expression Deconvolution Methods for Prediction of Pancreatic Ductal Adenocarcinoma” - Simons Summer Research Program (2019)
Banwasi A, Oh K, et al. “Simulation of Bulk Tumor Mixture Data and Evaluation of Cell Deconvolution Methods for Pancreatic Ductal Adenocarcinoma” - Simons Summer Research Program (2019)
Rao M, Nemajerova A, Li J, Oh K, et al. “Single-Cell RNA-Seq Analysis of Human Pancreatic Ductal Adenocarcinoma identifies an intestinal stem cell marker, OLFM4, as a potential barrier”. AACR Pancreatic Cancer Boston (2019)
Oh K, Kiser P, Palczewski K. “Expression and Characterization of Glutamyl Aminopeptidase”. SURP Summer Poster Presentation (2013)
Awards:
SUNY Graduate Research Empowering Accelerating Talent (GREAT) Award – 2022
NIH/NCI F30 Fellowship Award – Ruth L. Kirschstein Individual Predoctoral NRSA - 2020
1st Place Best Poster Award – Gloria & Mark Snyder Cancer Research Symposium - 2019
1st Place Best Poster Award – Stony Brook Cancer Center Research Symposium - 2019
2nd Place Best Poster Award – Stony Brook MSTP 36th Annual Retreat - 2018
SURF Award -American Society for Pharmacology & Experimental Therapeutics (ASPET) 2012
