Erin Sipple
Education:
B.S. in Neuroscience, Carnegie Mellon University (2018)
Current Position:
4th Year MSTP
2nd Year Graduate Student
Advisor:
Michelino Puopolo
Graduate Program:
PIN
Research Interest:
I am uniquely invested in studying chronic pain due to my own small fiber neuropathy/fibromyalgia, which gives me a valuable perspective on both the literature and the patient experience of some qualities of chronic pain (e.g., allodynia, hyperalgesia).
Currently, my research focuses on elucidating the contribution of T-type calcium channels, specifically Cav3.2, and the endocannabinoid system in the development/maintenance of chronic neuropathic pain following spinal cord injury (SCI). Using a rodent model of SCI, I investigate both the behavioral phenotypes of pain following SCI and the electrophysiological properties of the small diameter nociceptors cultured from the lumbar dorsal root ganglia of SCI-rodents.
Publications:
Liu, H., Lauzadis, J., Gunaratna, K., Sipple, E., Kaczocha, M., & Puopolo, M. (2023). Inhibition of T-Type Calcium Channels With TTA-P2 Reduces Chronic Neuropathic Pain Following Spinal Cord Injury in Rats. The Journal of Pain, S1526-5900(23)00404-2. Advance online publication. https://doi.org/10.1016/j.jpain.2023.05.002
Conference Posters/Presentations:
*E. SIPPLE1, H. LIU2, K. GUNARATNA2, J. LAUZADIS2, M. KACZOCHA2, M. PUOPOLO2; 1 Anesthesiol., Med. Scientist Training Program, Stony Brook, NY; 2 Anesthesiol., Stony Brook Med., Stony Brook, NY.
Targeting T-type calcium channels and the endocannabinoid system to treat SCI-induced neuropathic pain. Program No. 631.01. 2022 Neuroscience Meeting Planner. San Diego, CA: Society for Neuroscience, 2022. Online
K. GUNARATNA2, H. LIU2, *E. SIPPLE1, J. LAUZADIS2, M. KACZOCHA2, M. PUOPOLO2; 1 Anesthesiol., Med. Scientist Training Program, Stony Brook, NY; 2 Anesthesiol., Stony Brook Med., Stony Brook, NY.
Contribution of CaV3.2 calcium channels to nociceptors’ hyperexcitability and chronic neuropathic pain following spinal cord injury. Program No. 541.14. 2022 Neuroscience Meeting Planner. San Diego, CA: Society for Neuroscience, 2022. Online.
*A. R. LOCKER1,2, E. SIPPLE2, P. LIDSTONE2, D. VOLK2;
1Psychiatry, UPMC, Pittsburgh, PA; 2Univ. of Pittsburgh, Pittsburgh, PA.
Immune activation across the visuospatial working memory circuit in schizophrenia Program No. 435.04. 2017 Neuroscience Meeting Planner. Washington, D.C.: Society for Neuroscience, 2017. Online.
*Presenting Author
