Anthony Chesebro
Education:
B.S. Columbia University (2018)
Current Position:
4th Year MSTP
2nd Year Graduate Student
Advisor:
Lilianne R. Mujica-Parodi
Graduate Program:
Biomedical Medical Engineering
Website:
you.stonybrook.edu/agchesebro/
Research Interest:
My work is focused on quantitative and computational approaches to neuroimaging, as well as multi-scale modeling of neurobiological processes. My prior work has focused on quantifying MRI-based biomarkers of cerebrovascular disease and tying them to clinical measures of memory loss and vascular pathologies. Outside of research, I am also interested in the intersection between humanities and medicine, particularly through the lenses of narrative and performativity.
Publications:
Antal, BB, Chesebro, AG, Strey, HH, Mujica-Pardoi, LR, Weistuch, C. FixFit: deep learning for optimal model reduction. Preprint (under review). doi.org/10.13140/RG.2.2.25448.34565
van Nieuwenhuizen, H, Chesebro, AG, Polizu, C, Clarke, K, Strey, HH, Weistuch, C, Mujica-Parodi, LR. Ketosis regulates K+ ion channels, strengthening brain-wide signaling disrupted by age. Preprint (under review). doi.org/10.1101/2023.05.10.540257.
Morris, EP, Turney, IC, Palms, JD, Zaheed, AB, Sol, K, Amarante, E, Beato, J, Chesebro, AG, Morales, CD, Manly, JJ, Brickman, AM, & Zahodne, LB. (In Press). Racial/ethnic differences in the relationship between financial worry and white matter hyperintensities in Latinx, Non-Latinx Black, and Non-Latinx White older adults. Neurobiol. Aging.
Chesebro, AG, Mujica-Parodi, LR, Weistuch, C. Ion gradient-driven bifurcations of a multi-scale neuronal model. Chaos Solit. 2023 Feb; 167:113120.
Spagnolo-Allende, A, Schnall, R, Liu, M, Igwe, KC, Laing, KK, Chesebro, AG, Brickman, AM, Gutierrez, J. (Submitted December 2022). Serum inflammation markers associated with altered white matter microstructure in an older cohort of people with HIV on antiretroviral treatment. Neurol. Sci. (2023, Jan).
Lao, PJ, Boehme, AK, Morales, C, Laing, KK, Chesebro, AG, Igwe, K, Gutierrez, J, Gu, Y, Stern, Y, Schupf, N, Manly, JJ, Mayeux, R, Brickman, AM. Amyloid, cerebrovascular disease, and neurodegeneration biomarkers are associated with cognitive trajectories in a racially and ethnically diverse, community-based sample. Neurobiol. Aging. 2022 Sep;117:83-96.
Chesebro, AG. De Profundis: Oscar Wilde’s narrative of mental anguish. Hektoen Int. 2022 Winter; 14(1):hekint.org/2022/02/07/de-profundis-oscar-wildes-narrative-of-
mental-anguish/.
Igwe, KC, Lao, PJ, Vorburger, RS, Banerjee, A, Rivera, A, Chesebro, AG, Laing, KK, Manly, JJ, Brickman, AM. Automatic quantification of white matter hyperintensities on T2- weighted fluid attenuated inversion recovery magnetic resonance imaging. Magn Reson Imaging. 2022 Jan;85:71-79.
Rizvi B, Lao PJ, Chesebro AG, Dworkin JD, Amarante E, Beato JM, Gutierrez J, Zahodne LB, Schupf N, Manly JJ, Mayeux R, Brickman AM. Association of regional white matter hyperintensities with longitudinal Alzheimer-like pattern of neurodegeneration in older adults. JAMA Netw Open. 2021 Oct 1;4(10):e2125166.
Kreisl WC, Lao PJ, Johnson A, Tomljanovic Z, Klein J, Polly K, Maas B, Laing KK, Chesebro AG, Igwe K, Razlighi QR, Honig LS, Yan X, Lee S, Mintz A, Luchsinger JA, Stern Y, Devanand DP, Brickman AM. Patterns of tau pathology identified with 18F-MK-6240 PET imaging. Alzheimers Dement. 2021 May 31.
Chesebro AG, Amarante E, Lao PJ, Meier IB, Mayeux R, Brickman AM. Automated detection of cerebral microbleeds on T2*-weighted MRI. Sci Rep. 2021 Feb
17;11(1):4004.
Avila JF, Rentería MA, Jones RN, Vonk JMJ, Turney I, Sol K, Seblova D, Arias F, Hill-Jarrett T, Levy SA, Meyer O, Racine AM, Tom SE, Melrose RJ, Deters K, Medina LD, Carrión CI, Díaz-Santos M, Byrd DR, Chesebro AG, Colon J, Igwe KC, Maas B, Brickman AM, Schupf N, Mayeux R, Manly JJ. Education differentially contributes to cognitive reserve across racial/ethnic groups. Alzheimers Dement. 2021 Jan;17(1):70-80.
Gu Y, Beato JM, Amarante E, Chesebro AG, Manly JJ, Schupf N, Mayeux RP, Brickman AM. Assessment of leisure time physical activity and brain health in a multiethnic cohort of older adults. JAMA Netw Open. 2020 Nov 2;3(11):e2026506.
Turney IC, Chesebro AG, Rentería MA, Lao PJ, Beato JM, Schupf N, Mayeux R, Manly JJ, Brickman AM. APOE ε4 and resting-state functional connectivity in racially/ethnically diverse older adults. Alzheimers Dement (Amst). 2020 Sep 22;12(1):e12094.
Laing KK, Simoes S, Baena-Caldas GP, Lao PJ, Kothiya M, Igwe KC, Chesebro AG, Houck AL, Pedraza L, Hernández AI, Li J, Zimmerman ME, Luchsinger JA, Barone FC, Moreno H, Brickman AM; Alzheimer’s Disease Neuroimaging Initiative. Cerebrovascular disease promotes tau pathology in Alzheimer's disease. Brain Commun. 2020 Aug 19;2(2):fcaa132.
Domínguez-Vivero C, Wu L, Lee S, Manoochehri M, Cines S, Brickman AM, Rizvi B, Chesebro AG, Gazes Y, Fallon E, Lynch T, Heidebrink JL, Paulson H, Goldman JS, Huey E, Cosentino S. Structural Brain Changes in Pre-Clinical FTD MAPT Mutation Carriers. J Alzheimers Dis. 2020;75(2):595-606.
Chesebro AG, Melgarejo JD, Leendertz R, Igwe KC, Lao PJ, Laing KK, Rizvi B, Budge M, Meier IB, Calmon G, Lee JH, Maestre GE, Brickman AM. White matter hyperintensities mediate the association of nocturnal blood pressure with cognition. Neurology. 2020 Apr 28;94(17):e1803-e1810.
Stamm BC, Lao PJ, Rizvi B, Colon J, Igwe K, Chesebro AG, Maas B, Schupf N, Mayeux R, Manly JJ, Brickman AM. Parental History of Dementia Is Associated with Increased Small Vessel Cerebrovascular Disease. J Gerontol A Biol Sci Med Sci. 2020 Oct 15;75(11):2156-
2161.
