Eric Girardi
Education:
B.S. Brown University (2019)
Current Position:
3rd Year MSTP
1st Year Graduate Student
Advisor:
Chi-Kuo Hu
Graduate Program:
Research Interests:
I am interested in studying aging and senescence associated pathways. Aging is a major risk factor for almost all leading causes of death. Additionally, many diseases that decrease one’s quality of life increase in incidence and prevalence with age. Thus, I see aging as possibly the single largest factor contributing to decreases in healthspan and lifespan. In the dormant biology lab, I hope to use the shortest lived vertebrae, the African turquoise killifish (Nothobranchius furzeri) to study pathways related to diseases of aging. I am interested in neurodegenerative diseases Parkinson’s and Alzheimer’s, as well as the biomolecular pathways of aging from a broad perspective.
Publications:
Vargas KJ*, Colosi PL*, Girardi E* (*co-first authors), Park JM, Harmon LE, Chandra SS. α-Synuclein colocalizes with AP180 and affects the size of clathrin lattices [published online ahead of print, 2023 Jul 27]. J Biol Chem. 2023;105091. doi:10.1016/j.jbc.2023.105091
Yousuf H, Girardi EM, Crouse RB, Picciotto MR. Muscarinic antagonists impair multiple aspects of operant discrimination learning and performance. Neurosci Lett. 2023;794:137025. doi:10.1016/j.neulet.2022.137025
Crouse RB, Kim K, Batchelor HM, Girardi E, Kamaletdinova R, Chan J, Rajebhosale P,Pittenger ST, Role LW, Talmage DA, Jing M, Li Y, GaoX-B, Mineur YS, Picciotto MR. Acetylcholine is released in the basolateral amygdala in response to predictors of reward and enhances the learning of cue-reward contingency.eLife 2020;9:e57335http://dx.doi.org/10.7554/eLife.57335
