Natalie Lo
Education:
B.S. State Univesity of New York at Stony Brook (2021)
Current Position:
2nd Year MSTP
2nd Year Medical Student
Advisor:
TBA
Graduate Program:
TBA
Research Interests:
My undergraduate research in the field of DNA damage and repair focused on the fork protection complex protein, TIMELESS, and its role in protecting stalled replication forks to maintain genome stability. I am interested in further studying the mechanisms of other DNA repair pathways and their connection with cancer tumorigenesis to potentially develop cancer therapeutics that target these repair pathways.
Publications:
Weinheimer AS, Paung Y, Rageul J, Khan A, Lo N, Ho B, Tong M, Alphonse S, Seeliger M, Kim H. (2022) Extended DNA binding interfaces beyond the canonical SAP domain contribute to the function of replication stress regulator SDE2 at DNA replication forks. BioRxiv, doi.org/10.1101/2022.05.09.
Lo N, Rageul J, Kim H. (2020) Roles of SDE2 and TIMELESS at active and stalled DNA replication forks Mol. Cell Oncol. 8(1):1855053. doi: 10.1080/
23723556.2020.1855053.
Rageul J, Park JJ, Zeng PP, Lee E-A, Yang J, Hwang S, Lo N, Weinheimer AS, Schärer OD, Yeo J-E, Kim H. (2020) SDE2 integrates into the TIMELESS-TIPIN complex to protect stalled replication forks. Nature Communications. doi.org/10.
