Julian Maceren
Education:
B.S. University of Rochester (2020)
Current Position:
3rd Year MSTP
1st Year Graduate Student
Advisor:
Jessica Seeliger
Graduate Program:
Chemistry
Research Interests:
I am interested in using chemistry as a lens to examine biological systems and develop new therapeutics to treat and detect human diseases. As an undergrad, I first developed this interest while working in a nanomedicine lab where I created polymeric drug delivery systems to administer antibiotics. During my post-grad years, I synthesized small-molecule antibiotics and pioneered a high-throughput screening assay to examine their ability to penetrate bacterial membranes. I hope to continue pursuing research at the interface of chemistry and biology with a particular focus on understanding and treating neurodegenerative diseases.
Publications:
Sims, K. R.; Maceren, J. P.; Liu, Y.; Rocha, G. R.; Koo, H.; Benoit, D. S. W., Dual antibacterial drug-loaded nanoparticles synergistically improve treatment of Streptococcus mutans biofilms. Acta Biomaterialia 2020, 115, 418-431
Sims, K. R.; Maceren, J. P.; Strand, A. I.; He, B.; Overby, C.; Benoit, D. S. W., Rigor and reproducibility in polymer nanoparticle synthesis and characterization. RSC Advances 2020, 10 (5), 2513-2518
Fung, S. L.; Wu, X.; Maceren, J. P.; Mao, Y.; Kohn, J. “In Vitro Evaluation of Recombinant Bone Morphogenetic Protein-2 Activity for Regenerative Medicine,” Tissue Eng., Part C, 2019