Yunyoung Kim
Education:
B.A. Vassar College (2018)
Ph.D. Stony Brook University (2024)
Advisor:
Todd Miller
Graduate Program:
Molecular & Cellular Pharmacology
Research Interest:
Receptor tyrosine kinases regulate growth and differentiation in normal cells, and their dysregulation is frequently associated with cancer. My research focuses on how alterations in RTK signaling affect cellular behavior, with the goal of uncovering fundamental mechanisms that could guide the development of new therapies.
Publications:
Kim, Y., & Miller, W. T. (2024). Contrasting Effects of Cancer-Associated Mutations in EphA3 and EphB2 Kinases. Biochemistry, 10.1021/acs.biochem.3c00674.
Kim, Y., Ahmed, S., & Miller, W. T. (2023). Colorectal cancer-associated mutations impair EphB1 kinase function. The Journal of biological chemistry, 299(9), 105115.
Kan, Y., Paung, Y., Kim, Y., Seeliger, M. A., & Miller, W. T. (2023). Biochemical Studies of Systemic Lupus Erythematosus-Associated Mutations in Nonreceptor Tyrosine Kinases Ack1 and Brk. Biochemistry, 62(6), 1124–1137.
Crooks, D. R., Maio, N., Lang, M., Ricketts, C. J., Vocke, C. D., Gurram, S., Turan, S., Kim, Y. Y., Cawthon, G. M., Sohelian, F., De Val, N., Pfeiffer, R. M., Jailwala, P., Tandon, M., Tran, B., Fan, T. W., Lane, A. N., Ried, T., Wangsa, D., Malayeri, A. A., … Linehan, W. M. (2021). Mitochondrial DNA alterations underlie an irreversible shift to aerobic glycolysis in fumarate hydratase-deficient renal cancer. Science signaling, 14(664), eabc4436.
Kim, Y. Y., & Tanski, J. M. (2017). Crystal structure of a rare trigonal bipyramidal titanium(IV) coordination complex: tri-chlorido-(3,3'-di-tert-butyl-2'-hy-droxy-5,5',6,6'-tetra-methyl-1,1'-biphenyl-2-olato-κO2)(tetra-hydro-furan-κO)-titanium(IV). Acta crystallographica. Section E, Crystallographic communications, 73(Pt 1), 88–91.