Michael Pearl, MD, FACOG, FACS
Vice-Chair for Research and Faculty Development
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Full Bibliography
1. Pearl ML, Zhao Q, Yang J, Dong H, Tulley S, Zhang Q, Golightly M, Zucker S, Chen WT. Prognostic analysis of invasive circulating tumor cells (iCTCs) in epithelial ovarian cancer. Gynecol Oncol. 2014 Sep;134(3):581-90. PMID: 24972191;PMCID: PMC4160464.
2. Stevens EE, Yu S, Van Sise M, Pradhan TS, Lee V, Pearl ML, Lee YC, Abulafia O. Hemoglobin A1c and the relationship to stage and grade of endometrial cancer. Arch Gynecol Obstet. 2012 Dec;286(6):1507-12. PMID: 22797661.
3. McMeekin DS, Sill MW, Darcy KM, Abulafia O, Hanjani P, Pearl ML, Rubin SC, Rose PG, Small L, Benbrook DM. A phase II trial of thalidomide in patients with refractory uterine carcinosarcoma and correlation with biomarkers of angiogenesis: a Gynecologic Oncology Group study. Gynecol Oncol. 2012 Nov;127(2):356-61. PMID: 22796461.
4. Walker JL, Piedmonte MR, Spirtos NM, Eisenkop SM, Schlaerth JB, Mannel RS, Barakat R, Pearl ML, Sharma SK. Recurrence and survival after random assignment to laparoscopy versus laparotomy for comprehensive surgical staging of uterine cancer: Gynecologic Oncology Group LAP2 Study. J Clin Oncol. 2012 Mar 1;30(7):695-700. Erratum in: J Clin Oncol. 2012 May 1;30(13):1570. PMID: 22291074;PMCID: PMC3295548.
5. Hurteau JA, Brady MF, Darcy KM, McGuire WP, Edmonds P, Pearl ML, Ivanov I, Tewari KS, Mannel RS, Zanotti K, Benbrook DM. Randomized phase III trial of tamoxifen versus thalidomide in women with biochemical-recurrent-only epithelial ovarian, fallopian tube or primary peritoneal carcinoma after a complete response to first-line platinum/taxane chemotherapy with an evaluation of serum vascular endothelial growth factor (VEGF): A Gynecologic Oncology Group Study. Gynecol Oncol. 2010 Dec;119(3):444-50. PMID: 20846715.
6. Walker JL, Piedmonte MR, Spirtos NM, Eisenkop SM, Schlaerth JB, Mannel RS, Spiegel G, Barakat R, Pearl ML, Sharma SK. Laparoscopy compared with laparotomy for comprehensive surgical staging of uterine cancer: Gynecologic Oncology Group Study LAP2. J Clin Oncol. 2009 Nov 10;27(32):5331-6. PMID: 19805679; PMCID: PMC2773219.
7. Miller DS, Blessing JA, Krasner CN, Mannel RS, Hanjani P, Pearl ML, Waggoner SE, Boardman CH. Phase II evaluation of pemetrexed in the treatment of recurrent or persistent platinum-resistant ovarian or primary peritoneal carcinoma: a study of the Gynecologic Oncology Group. J Clin Oncol. 2009 Jun 1;27(16):2686-91. PMID: 19332726; PMCID: PMC2690393.
8. Fan T, Zhao Q, Chen JJ, Chen WT, Pearl ML. Clinical significance of circulating tumor cells detected by an invasion assay in peripheral blood of patients with ovarian cancer. Gynecol Oncol. 2009 Jan;112(1):185-91. PMID: 18954898; PMCID: PMC2606929.
9. Kavanagh JJ, Sill MW, Ramirez PT, Warshal D, Pearl ML, Morgan MA. Phase II multicenter open-label study of karenitecin in previously treated epithelial ovarian and primary peritoneal cancer: a Gynecologic Oncology Group Study. Int J Gynecol Cancer. 2008 May-Jun;18(3):460-4. PMID: 17854432.
10. Liang SX, Pearl M, Liu J, Hwang S, Tornos C. "Malignant" uterine perivascular epithelioid cell tumor, pelvic lymph node lymphangioleiomyomatosis, and gynecological pecomatosis in a patient with tuberous sclerosis: a case report and review of the literature. Int J Gynecol Pathol. 2008 Jan;27(1):86-90. PMID: 18156981.
11. Liang SX, Patel K, Pearl M, Liu J, Zheng W, Tornos C. Sertoliform endometrioid carcinoma of the endometrium with dual immunophenotypes for epithelial membrane antigen and inhibin alpha: case report and literature review. Int J Gynecol Pathol. 2007 Jul;26(3):291-7. PMID: 17581414.
12. Howell NR, Zheng W, Cheng L, Tornos C, Kane P, Pearl M, Chalas E, Liang SX. Carcinomas of ovary and lung with clear cell features: can immunohistochemistry help in differential diagnosis? Int J Gynecol Pathol. 2007 Apr;26(2):134-40. PMID: 17413979.
13. Pearl ML, Johnston CM, McMeekin DS. A phase II study of weekly docetaxel for patients with advanced or recurrent cancer of the cervix. Gynecol Obstet Invest. 2007;64(4):193-8. PMID: 17664880.
14. DiSilvestro PA, Fisher M, Pearl ML, Buhl A, Chalas E, Valea FA. Pilot phase 2 trial of 4 months of maintenance pegylated liposomal Doxorubicin in patients with advanced ovarian cancer after complete response to platinum and Paclitaxel-based chemotherapy. Gynecol Obstet Invest. 2007;63(1):1-6. PMID: 16809933.
15. Chen D, Kennedy A, Wang JY, Zeng W, Zhao Q, Pearl M, Zhang M, Suo Z, Nesland JM, Qiao Y, Ng AK, Hirashima N, Yamane T, Mori Y, Mitsumata M, Ghersi G, Chen WT. Activation of EDTA-resistant gelatinases in malignant human tumors. Cancer Res. 2006 Oct 15;66(20):9977-85. PMID: 17047060; PMCID: PMC1626657.
16. Liang S, Stone G, Chalas E, Pearl M, Callan F, Zheng W. A high-grade uterine leiomyosarcoma with human chorionic gonadotropin production. Int J Gynecol Pathol. 2006 Jul;25(3):257-61. PMID: 16810064.
17. Muggia FM, Blessing JA, Waggoner S, Berek JS, Monk BJ, Sorosky J, Pearl ML. Evaluation of vinorelbine in persistent or recurrent nonsquamous carcinoma of the cervix: a Gynecologic Oncology Group Study. Gynecol Oncol. 2005 Jan;96(1):108-11. PMID: 15589588.
18. Schilder RJ, Blessing JA, Pearl ML, Rose PG. Evaluation of irofulven (MGI-114) in the treatment of recurrent or persistent endometrial carcinoma: A phase II study of the Gynecologic Oncology Group. Invest New Drugs. 2004 Aug;22(3):343-9. PMID: 15122083.
19. Pearl ML, Rayburn WF. Choosing abdominal incision and closure techniques: a review. J Reprod Med. 2004 Aug;49(8):662-70. Review. PMID: 15457857.
20. Pearl ML, Inagami M, McCauley DL, Valea FA, Chalas E, Fischer M. Mesna, doxorubicin, ifosfamide, and dacarbazine (MAID) chemotherapy for gynecological sarcomas. Int J Gynecol Cancer. 2002 Nov-Dec;12(6):745-8. PMID: 12445253.
21. Chaudhry TL, Valea FA, Pearl ML, DiSilvestro PA, Fischer M, Chalas E. Primary care experience on a university-based oncology service. Prim Care Update Ob Gyns. 2002 9:57-60.
22. Pearl ML, Villella JA, Valea FA, DiSilvestro PA, Chalas E. Outcomes of endometrial cancer patients undergoing surgery with gynecologic oncology involvement. Obstet Gynecol. 2002 Oct;100(4):724-9. PMID: 12383541.
23. Zaika AI, Slade N, Erster SH, Sansome C, Joseph TW, Pearl M, Chalas E, Moll UM. DeltaNp73, a dominant-negative inhibitor of wild-type p53 and TAp73, is up-regulated in human tumors. J Exp Med. 2002 Sep 16;196(6):765-80. PMID: 12235210; PMCID: PMC2194062.
24. Villella JA, Chaudhry T, Pearl ML, Valea F, DiSilvestro PA, Pollack S, Chalas E. Comparison of tolerance of combination carboplatin and paclitaxel chemotherapy by age in women with ovarian cancer. Gynecol Oncol. 2002 Sep;86(3):316-22. PMID: 12217754.
25. Pearl ML, Frandina M, Mahler L, Valea FA, DiSilvestro PA, Chalas E. A randomized controlled trial of a regular diet as the first meal in gynecologic oncology patients undergoing intraabdominal surgery. Obstet Gynecol. 2002 Aug;100(2):230-4. PMID: 12151142.
26. Pearl ML, McCauley DL, Thompson J, Mahler L, Valea FA, Chalas E. A randomized controlled trial of early oral analgesia in gynecologic oncology patients undergoing intra-abdominal surgery. Obstet Gynecol. 2002 May;99(5 Pt 1):704-8. PMID: 11978276.
27. Shibutani S, Ravindernath A, Suzuki N, Terashima I, Sugarman SM, Grollman AP, Pearl ML. Identification of tamoxifen-DNA adducts in the endometrium of women treated with tamoxifen. Carcinogenesis. 2000 Aug;21(8):1461-7. PMID: 10910945.
28. Pearl ML, Valea FA, Disilvestro PA, Chalas E. Panniculectomy in morbidly obese gynecologic oncology patients. Int J Surg Investig. 2000;2(1):59-64. PMID: 12774339.
29. Pearl ML, Fischer M, McCauley DL, Valea FA, Chalas E. Transcutaneous electrical nerve stimulation as an adjunct for controlling chemotherapy-induced nausea and vomiting in gynecologic oncology patients. Cancer Nurs. 1999 Aug;22(4):307-11. PMID: 10452208.
30. Shibutani S, Suzuki N, Terashima I, Sugarman SM, Grollman AP, Pearl ML. Tamoxifen-DNA adducts detected in the endometrium of women treated with tamoxifen. Chem Res Toxicol. 1999 Jul;12(7):646-53. PMID: 10409405.
31. Pearl ML, Valea FA, Fischer M, Mahler L, Chalas E. A randomized controlled trial of early postoperative feeding in gynecologic oncology patients undergoing intra-abdominal surgery. Obstet Gynecol. 1998 Jul;92(1):94-7. PMID: 9649101.
32. Pearl ML, Valea FA, Chalas E. Panniculectomy and supraumbilical vertical midline incisions in morbidly obese gynecologic oncology patients. J Am Coll Surg. 1998 Jun;186(6):649-53. PMID: 9632152.
33. Pearl ML, Talgat G, Valea FA, Chalas E. Psychiatric symptoms due to brain metastases. Med Update Psychiatr. 1998 3:91-94.
34. Jamis-Dow CA, Pearl ML, Watkins PB, Blake DS, Klecker RW, Collins JM. Predicting drug interactions in vivo from experiments in vitro. Human studies with paclitaxel and ketoconazole. Am J Clin Oncol. 1997 Dec;20(6):592-9. PMID: 9391548.
35. Pearl ML, Griffen T, Valea FA, Chalas E. The utility of pretreatment barium enema in women with endometrial carcinoma. Gynecol Oncol. 1997 Mar;64(3):442-5. PMID: 9062147.
36. Pearl ML, Valea FA, Chalas E. Brain metastases. Prim Care Update Ob Gyns. 1997 4:127-130.
37. Valea FV, Sherwood J, Chalas E, Pearl ML. Evaluation of surgical risk factors in an elderly population undergoing major gynecologic surgery by a gynecologic oncology service. Prim Care Update Ob Gyns. 1997 4:1-4.
38. Toglia MR, Coburn KM, Pearl ML. Evaluation of colposcopic skills in an obstetrics and gynecology residency training program. J Lower Genital Tract Dis. 1997 1:5-8.
39. Pearl ML, Valea FA, Fischer M, Chalas E. A randomized controlled trial of postoperative nasogastric tube decompression in gynecologic oncology patients undergoing intra-abdominal surgery. Obstet Gynecol. 1996 Sep;88(3):399-402. PMID: 8752247.
40. Gretz HF3rd, Economos K, Husain A, Lesser M, Kaplan E, Caputo TA, Reynolds RK, Johnston CM, Pearl ML, Roberts JA. The practice of surgical staging and its impact on adjuvant treatment recommendations in patients with stage I endometrial carcinoma. Gynecol Oncol. 1996 Jun;61(3):409-15. PMID: 8641624.
41. Gardella C, Chumas JC, Pearl ML. Ovarian lipoma of teratomatous origin. Obstet Gynecol. 1996 May;87(5 Pt 2):874-5. PMID: 8677122.
42. Pearl ML, Valea F, Chumas J, Chalas E. Primary retroperitoneal mucinous cystadenocarcinoma of low malignant potential: a case report and literature review. Gynecol Oncol. 1996 Apr;61(1):150-2. Review. PMID: 8626105.
43. Pearl ML, McCauley DL. Management of hypercalcemia of malignancy. Prim Care Update Ob Gyns. 1996 3:163-166.
44. Pearl ML, McCauley DL. High-dose chemotherapy and stem cell rescue for the treatment of gynecologic malignancies. Prim Care Update Ob Gyns. 1996 3:135-142.
45. Pearl ML, Escamilla G, Karpel BM, Kaplan C, Jones C, Westermann C. Conservative management of placenta percreta with involvement of the ileum. Arch Gynecol Obstet. 1996;258(3):147-50. PMID: 8781703.
46. Pearl ML, Johnston CM, Reynolds RK, Roberts JA. Absence of cumulative bone marrow suppression in heavily pretreated ovarian cancer patients undergoing salvage chemotherapy with paclitaxel. Oncology. 1995 Sep-Oct;52(5):407-12. PMID: 7543668.
47. Selvaggi SM, Haefner HK, Lelle RJ, Pearl ML, Roberts JA. Neovaginal cytology after total pelvic exenteration for gynecological malignancies. Diagn Cytopathol. 1995 Jul;13(1):22-5. PMID: 7587870.
48. Talavera F, Bergman C, Pearl ML, Connor P, Roberts JA, Menon KM. cAMP and PMA enhance the effects of IGF-I in the proliferation of endometrial adenocarcinoma cell line HEC-1-A by acting at the G1 phase of the cell cycle. Cell Prolif. 1995 Mar;28(3):121-36. PMID: 7734622.
49. Johnston CM, Pearl ML, Reynolds RK, Roberts JA, Morley GW. Treatment of refractory ovarian carcinoma with paclitaxel and cisplatin after treatment failure with single-agent paclitaxel. Eur J Gynaecol Oncol. 1995;16(6):439-47. PMID: 8536758.
50. Johnston CM, Pearl ML. Absence of an association between G-CSF support and clinical response in heavily pre-treated ovarian cancer patients receiving salvage chemotherapy with paclitaxel (Taxol). Eur J Gynaecol Oncol. 1995;16(4):251-7. PMID: 7556279.
51. Pearl ML, Yashar CM, Johnston CM, Reynolds RK, Roberts JA. Exponential regression of CA 125 during salvage treatment of ovarian cancer with taxol. Gynecol Oncol. 1994 Jun;53(3):339-43. PMID: 7911444.
52. Gretz HF 3rd, Talavera F, Connor P, Pearl M, Lelle RJ, Roberts JA, Menon KM. Protein kinase C-dependent and -independent pathways mediate epidermal growth factor (EGF) effects in human endometrial adenocarcinoma cell line KLE. Gynecol Oncol. 1994 May;53(2):228-33. PMID: 8188084.
53. Hurd WW, Randolph JF Jr, Holmberg RA, Pearl ML, Hubbell GP. Open laparoscopy without special instruments or sutures. Comparison with a closed technique. J Reprod Med. 1994 May;39(5):393-7. PMID: 8064707.
54. Pearl ML, Johnston CM, Frank TS, Roberts JA. Synchronous dual primary ovarian and endometrial carcinomas. Int J Gynaecol Obstet. 1993 Dec;43(3):305-12. PMID: 7907042.
55. Pearl ML, Roberts JM, Laros RK, Hurd WW. Vaginal delivery from the persistent occiput posterior position. Influence on maternal and neonatal morbidity. J Reprod Med. 1993 Dec;38(12):955-61. PMID: 8120853.
56. Hurd WW, Pearl ML, DeLancey JO, Quint EH, Garnett B, Bude RO. Laparoscopic injury of abdominal wall blood vessels: a report of three cases. Obstet Gynecol. 1993 Oct;82(4 Pt 2 Suppl):673-6. PMID: 8378008.
57. Crawford LA, Quint EH, Pearl ML, DeLancey JO. Incontinence following rupture of the anal sphincter during delivery. Obstet Gynecol. 1993 Oct;82(4 Pt 1):527-31. PMID: 8377977.
58. Pearl ML, Talavera F, Gretz HF 3rd, Roberts JA, Menon KM. Mitogenic activity of growth factors in the human endometrial adenocarcinoma cell lines HEC-1-A and KLE. Gynecol Oncol. 1993 Jun;49(3):325-32. PMID: 8314534.
59. Pearl ML, Beretta S. Routine endometrial curettage is not indicated at the time of cervical cone biopsy. Surg Gynecol Obstet. 1993 Mar;176(3):251-4. PMID: 8438197.
60. Livingston EG, Guis MS, Pearl ML, Stern JL, Brescia RJ. Diffuse adenomatoid tumor of the uterus with a serosal papillary cystic component. Int J Gynecol Pathol. 1992 Oct;11(4):288-92. PMID: 1399234.
61. Pearl ML, Braga CA. Percutaneous transcatheter embolization for control of life-threatening pelvic hemorrhage from gestational trophoblastic disease. Obstet Gynecol. 1992 Sep;80(3 Pt 2):571-4. PMID: 1323089.
62. Hurd WW, Bude RO, DeLancey JO, Pearl ML. The relationship of the umbilicus to the aortic bifurcation: implications for laparoscopic technique. Obstet Gynecol. 1992 Jul;80(1):48-51. PMID: 1534882.
63. Pearl ML, Crombleholme WR, Green JR, Bottles K. Fibroepithelial polyps of the vagina in pregnancy. Am J Perinatol. 1991 Jul;8(4):236-8. Review. PMID: 1741864.
64. Pearl ML, Major C, Coyne B. Asynchronous bilateral adnexal torsion in a prepubertal girl: a case report and review of the world literature. J Pediatr Adolesc Gynecol. 1990 3:197-200.
65. Pearl ML, Dattel BJ. The pulse oximeter for respiratory distress associated with pyelonephritis in pregnancy. A case report. J Reprod Med. 1990 Jul;35(7):724-6. PMID: 2376859.
