Sruthi Babu
MD, PhD, MPH
Associate Professor
University Hospital Level 2, Rm 762
Stony Brook Medicine
Stony Brook, NY 11794-7025
Tel: (631) 444-2222
Fax: (631) 444-3419
Email: sruthi.babu@stonybrookmedicine.edu
Clinical Practice:
Dr. Babu is Board Certified in Clinical Pathology (2024) and Anatomical Pathology (2024).
Education:
2017- 2020: PhD. - Population Health and Clinical Outcome Program, Department of Pathology, Renaissance School of Medicine, Stony Brook University, Stony Brook, NY, USA
2015- 2017: Master of Public Health – Epidemiology, Rutgers School of Public Health, Piscataway, NJ, USA
2000- 2007: Bachelor of Medicine, Bachelor of Surgery, Jagadguru Sri Shivarathreeswara Medical College (J.S.S.), Mysore, India
Residency and Fellowship Training:
2024-2025: Hematopathology Fellow, Department of Pathology, Renaissance School of Medicine, Stony Brook University, Stony Brook, NY, USA
2020- 2024: Resident, Department of Pathology, Renaissance School of Medicine Stony Brook University, Stony Brook, NY, USA
2012 -2014: Residency in Clinical Pathology, Jagadguru Jayadevan Murugarajendra Medical College (J.J.M.), Davangere, India
Current and Previous Appointments:
2025 - Present, Clinical Assistant Professor, Department of Pathology, Stony Brook University Hospital, Stony Brook, NY
Peer Reviewed Publications:
Babu, S., Mockler, D.C., Roa-Pena, L., Szygalowicz, A., Kim, N.W., Jahanfard, S., Escobar-Hoyos, L.F., and K.R. Shroyer. Keratin 17 is a sensitive and specific biomarker of urothelial neoplasia. Mod Pathol. 2019 May; 32(5):717-724. PMID: 30443013.
Babu S, Kim NW, Wu M, Chan I, Escobar-Hoyos LF, Shroyer KR. Keratin 17 Is a Novel Cytologic Biomarker for Urothelial Carcinoma Diagnosis. Am J Clin Pathol. 2021 Oct 13;156(5):926-933. PMID: 34086841.
Babu S, Horowitz M, Delgado-Coka LA, Roa-Peña L, Akalin A, Escobar-Hoyos LF, Shroyer KR. Keratin 17 and A2ML1 are negative prognostic biomarkers in non-small cell lung cancer. Pathol Res Pract. 2024 Nov; 263:155643. PMID: 39413460.
Roa-Peña, L. Leiton, CV. Babu, S. Vanner, EA. Pan, C. Akalin, A. Bandovic, J. Moffitt, R. Escobar-Hoyos, LF. Shroyer, KR. Keratin 17 identifies and drives the most lethal form of pancreatic cancer. Sci Rep. 2019 Aug 2;9(1):11239. PMID: 31375762.
Roa-Peña L, Babu S, Leiton CV, Wu M, Taboada S, Akalin A, Buscaglia J, Escobar-Hoyos LF, Shroyer KR. Keratin 17 testing in pancreatic cancer needle aspiration biopsies predicts survival. Cancer Cytopathol. 2021 Nov; 129(11):865-873. PMID: 34076963.
Bai JDK, Babu S, Roa-Peña L, Hou W, Akalin A, Escobar-Hoyos LF, Shroyer KR. Keratin 17 is a negative prognostic biomarker in high-grade endometrial carcinomas. Hum Pathol. 2019 Dec; 94:40-50. PMID: 31655172.
Haye K, Babu S, Oblein L, Gupta R, Akalin A, Escobar-Hoyos LF, Shroyer KR. Keratin 17 Expression Predicts Poor Clinical Outcome in Patients with Advanced Esophageal Squamous Cell Carcinoma. Appl Immunohistochem Mol Morphol. 2021 Feb 1;29(2):144-151. PMID: 32554975.
Pan CH, Otsuka Y, Sridharan B, Woo M, Leiton CV, Babu S, Torrente Gonçalves M, Kawalerski RR, K Bai JD, Chang DK, Biankin AV, Scampavia L, Spicer T, Escobar-Hoyos LF, Shroyer KR. An unbiased high-throughput drug screen reveals a potential therapeutic vulnerability in the most lethal molecular subtype of pancreatic cancer. Mol Oncol. 2020 Aug;14(8):1800-1816. PMID: 32533886.
Yuen JG, Marshilok AC, Benziger PT, Yan S, Cello J, Stackhouse CA, Kisslinger K, Bock DC, Takeuchi ES, Takeuchi KJ, Wang L, Babu S, Itzkowitz G, Thanassi D, Knopf DA, Shroyer KR. Dry heat sterilization as a method to recycle N95 respirator masks: The importance of fit. PLoS One. 2022 Jan 5;17(1). PMID: 34986162.
Escobar-Hoyos LF, Penson A, Kannan R, Cho H, Pan CH, Singh RK, Apken LH, Hobbs GA, Luo R, Lecomte N, Babu S, Pan FC, Alonso-Curbelo D, Morris JP 4th, Askan G, Grbovic-Huezo O, Ogrodowski P, Bermeo J, Saglimbeni J, Cruz CD, Ho YJ, Lawrence SA, Melchor JP, Goda GA, Bai K, Pastore A, Hogg SJ, Raghavan S, Bailey P, Chang DK, Biankin A, Shroyer KR, Wolpin BM, Aguirre AJ, Ventura A, Taylor B, Der CJ, Dominguez D, Kümmel D, Oeckinghaus A, Lowe SW, Bradley RK, Abdel-Wahab O, Leach SD. Altered RNA Splicing by Mutant p53 Activates Oncogenic RAS Signaling in Pancreatic Cancer. Cancer Cell. 2020 Aug 10;38(2):198-211. PMID: 32559497.
Delgado-Coka LA, Roa-Peña L, Babu S, Horowitz M, Petricoin EF 3rd, Matrisian LM, Blais EM, Marchenko N, Allard FD, Akalin A, Jiang W, Larson BK, Hendifar AE, Picozzi VJ, Choi M, Shroyer KR, Escobar-Hoyos LF. Keratin 17 is a prognostic and predictive biomarker in pancreatic ductal adenocarcinoma. Am J Clin Pathol. 2024 Sep 3;162(3):314-326. PMID: 38642081
Delgado-Coka LA, Horowitz M, Torrente-Goncalves M, Roa-Peña L, Leiton CV, Hasan M, Babu S, Fassler D, Oentoro J, Karen Bai JD, Petricoin EF, Matrisian LM, Blais EM, Marchenko N, Allard FD, Jiang W, Larson B, Hendifar A, Chen C, Abousamra S, Samaras D, Kurc T, Saltz J, Escobar-Hoyos LF, Shroyer K. Keratin 17 modulates the immune topography of pancreatic cancer. J Transl Med. 2024 May 10;22(1):443. PMID: 38464123.
