Spring
HBY531 - Medical Physiology
HBY 554 - Principles of Neuroscience
HBY 557 - Advanced Physiology
HBY 561 - Statistical Analysis of Physiological Data
HBY 562 - Model-based Analysis of Physiological Data
HBY 564 - Experimental Techniques in Systems Physiology
HBY 565 - Mathematical Models of Physiologic & Biophysical Systems
Summer
Fall
HBY350 - Human Physiology
HBY 530 - Cellular Physiology and Biophysics
Course Descriptions
HBY 350 Human Physiology
The normal functioning of human tissues and organs and their regulation by the nervous and endocrine systems. Special emphasis is given to physiological control systems and the preservation of the constancy of the internal environment. Lectures, conferences, demonstrations. Priority given to Health Sciences students. Fall term. Prerequisites: U3 or U4 standing; College courses in biology and chemistry; Permission of the instructor. Advisory Prerequisite: Some background in physical science.
4 credits
HBY 393, 394 Special Topics from Physiology and Biophysics Literature
Tutorial readings in physiology and biophysics and periodic conferences, reports, and examinations arranged with the instructor. May be repeated. Prerequisites: U3 or U4 standing; Permission of the instructor.
1-2 credits per course
HBY 398, 399 Research Project in Physiology and Biophysics
An independent research project under faculty supervision, with emphasis on the principles of experimental design, data collection, evaluation of findings, and reporting of results. The student is expected to prepare a report on the project and be able to discuss his or her work. May be repeated. Prerequisites: U3 or U4 standing; laboratory experience; Permission of the supervising instructor. Advisory Prerequisite: Some background in physical science.
0-4 credits
HBY 530 Cellular Physiology and Biophysics
Cellular structure and function. Topics include ion channels excitability, transport, energetics and metabolism, contraction, secretion, and communication within and between cells. Emphasizes quantitative analysis of cellular processes. The course includes a laboratory with demonstrations and discussions of current issues in cellular physiology and biophysics. Fall term. ABCF Grading.Prerequisites: Undergraduate physics, physical chemistry, biochemistry, biology, calculus, and permission of instructor.
3 credits
HBY 531 Medical Physiology
A graduate-level introduction to the physiology of organ systems with ultrastructural correlations. Ultrastructural correlations are demonstrated in a laboratory setting using histological preparations in conjunction with eletron micrographs illustrating the relevant ultrastructure needed to understand the normal functioning of tissues and organs. The physiology of the major organ systems is addressed in a lecture format with the emphasis on problem solving. Relevant clinical correlations are addressed at the end of each block insofar as they illustrate how symptoms and signs of disease result from disordered physiology. Medical Physiology addresses the structure and function of the cardiovascular, respiratory, renal, gastrointestinal, endocrine, skeletal, reproductive, and integumenary systems. Spring term. ABCF Grading. Prerequisites: Admission to medical or dental school, and permission of instructor.
8 credits
HBY 553 Signal Transduction
The course will emphasize fundamental concepts in signal transduction (e.g., membrane-protein and protein-protein interactions, amplification of signals) and individual lecturers will apply these concepts at each stage of cell signalling from the cell surface to the nucleus, where signal transduction leads to specific gene expression. Spring term (odd years). ABCF Grading.
3 credits
HBY 554 Principles of Neuroscience
The aim of this course is to highlight and create an understanding as to how the human nervous system operates. Fall term. ABCF Grading. Prerequisites: Undergraduate biochemistry, biology and chemistry. Permission of instructor.
3 credits
HBY 557 Advanced Physiology
This course is designed to introduce students to integrative approaches in biomedical research. Emphasis will be placed on the primary physiological concepts of control, communication, signal processing, metabolism, and replication. Spring term. ABCF Grading.
3 credits
HBY 561 Statistical Analysis of Physiological Data
Statistical methods useful in analyzing common types of physiological data. Topics include probability, data distributions, hypothesis testing with parametric and non-parametric methods, ANOVA, regression correlation, and power analysis. Emphasis on experimental design, and approriate, efficient use of statistical software. Spring term. ABCF Grading.
1 credits
HBY 562 Model-based Analysis of Physiological Data
The analysis of common biochemical and physiological data by non-linear regression of data models and biophysical models of physiological and biochemical process. Examples include binding kinetics, compartmental mass transfer, and spectral analysis. Spring term. ABCF Grading.
1 credits
HBY 564 Experimental Techniques in Systems Physiology
A series of lectures and laboratory exercises designed to introduce students to in vivo experimental techniques used in systems physiology. Emphasis will be placed on the ethical use of rodents in biomedical reasearch and the measurement of physiological variables. Data acquisition and analysis procedures used in cardiovascular, respiratory, neural, and renal physiology will also be covered. Spring term. ABCF Grading.
2 credits
HBY 565 Mathematical Models of Physiologic & Biophysical Systems
An introduction to mathematical modeling of cell and tissue function. Topics include the derivation and numerical solution of models of cell homeostasis, membrane transport and excitability, and cell signaling an metabolism. Grading is based on problems, stucent presentations, and completion of a modeling project. Spring term. ABCF Grading.
3 credits
HBY 570 Student Journal Club
Graduate student presentations on a selected topic with faculty consultation. Spring and Fall terms. S/U Grading. Repetitive. Prerequisites: Limited to students of the Physiology ans Biophysics program.
1 credit per semester
HBY 590 Special Topics in Physiology and Biophysics
Student seminars and tutorials on advanced topics to be arranged through consultation with faculty members. Spring and Fall terms. ABCF Grading. Repetitive. Prerequisites: Permission of instructor.
1 credits per semester
HBY 591 Physiology and Biophysics Research
Original investigation undertaken with a member of the faculty. Spring and Fall terms. ABCF Grading. Repetitive. Prerequisites: Permission of instructor.
1-12 credits per semester
HBY 690 Seminar in Physiology and Biophysics
Seminars and discussions on major topics in physiology and biophysics by students, faculy, and visiting scientists. Spring and Fall terms. S/U Grading. Repetitive.
1 credits per semester
HBY 695 Practicum in Teaching in Physiology and Biophysics
Practical experience and instruction in the teaching of physiology and biophysics carried out under faculty supervision. Spring Summer, and Fall terms. ABCF Grading. Repetitive. Prerequisites: Advancement to candidacy.
1 credits per semester
HBY 699 Dissertation Research on Campus
Original (thesis) research undertaken with the supervision of a member of the staff. Spring Summer, and Fall terms. ABCF Grading. Repetitive. Prerequisites: Advancement to candidacy.
1-12 credits per semester
HBY 800 Summer Research
Full-time laboratory research projects supervised by faculty members. Summer term. S/U Grading. Repetitive. Prerequisites: Permission of instructor and full-time graduate status.
no credit
