Achievements 2021 - 2022

Grants, Fellowships, and Awards

Gaudino, Stephen (2021). Irving Abrahams Award for Outstanding Achievement by a Graduate Student. Department of Microbiology and Immunology, Stony Brook University.

Gaudino, Stephen (2021). Outstanding Poster Award. Department of Microbiology and Immunology Annual Retreat

Kempen, Cody (2021). Outstanding Poster Award. Department of Microbiology and Immunology Annual Retreat

Lanze, Carla (2021). Outstanding Poster Award. Department of Microbiology and Immunology Annual Retreat

Mendoza, Alicia (2022). State University of New York Graduate Research Empowering and Accelerating Talent (GREAT) Award.

Swenson, Kare (2021). Distinguished Service Award. Department of Microbiology and Immunology Annual Retreat

Jointly Authored Publications/Research Reports/Reviews

Banerjee, K., Motley, M.P., Boniche-Alfaro, C., Bhattacharya, S., Shah, R., Ardizzone, A., and Fries, B.C. (2022). Patient-derived antibody data yields development of broadly cross-protective monoclonal antibody against ST258 carbapenem-resistant Klebsiella pneumoniae. Microbial Spectrum, in press.

Bryan, A.M., You, J.K., Li, G., Kim, J., Singh, A., Morstein, J., Trauner, D., Pereira de Sa, N., Normile, T.G., Farnoud, A.M, London, E., and Del Poeta, M. (2021). Cholesterol and sphingomyelin are critical for Fcγ receptor-mediated phagocytosis of Cryptococcus neoformans by macrophages. Journal of Biological Chemistry 297(6): 101411.

Bettke, J.A., Tam, J.W., Montoya, V., Butler, B.P., and van der Velden, A.W.M. (2022). Inflammatory monocytes promote granuloma-mediated control of persistent Salmonella infection. Infection and Immunity 90(4): e0007022.

Chikhalya, A., Dittmann, M., Zheng, Y., Sohn, S.-Y., Rice, C.M., and Hearing, P. (2021). Human IFIT3 protein induces interferon signaling and inhibits adenovirus immediate early gene expression. mBio 12(6): e0282921.

Chu, T.H., Qiu, Z., and Sheridan, B.S. (2022). The use of foodborne infection to evaluate bacterial pathogenesis and host response. Methods in Cell Biology 168: 299-314.

Chu, T.H., Khairallah, C., Shieh, J., Cho, R, Qiu, Z., Zhang, Y., Eskiocak, O., Thanassi, D.G., Kaplan, M.H., Beyaz, S., Yang, V.W., Bliska, J.B., and Sheridan, B.S. (2021). γδ T cell IFNγ production is directly subverted by Yersinia pseudotuberculosis outer protein YopJ in mice and humans. PLos Pathogens 17(12): e1010103.

Conde, J.N., Sanchez-Vicente, S., Saladino, N., Gorbunova, E.E., Schutt, W.R., Mladinich, M.C., Himmler, G.E., Benach, J., Kim, H.K., and Mackow, E.R. (2022). Powassan viruses spread cell to cell during direct isolation from Ixodes ticks and persistently infect human brain endothelial cells and pericytes. Journal of Virology 96(1): e02168221.

Du, M., Yuan, Z., Werneburg, G.T., Henderson, N.S., Chauhan, H., Kovach, A., Zhao, G., Johl, J., Li, H., and Thanassi, D.G. (2021). Processive dynamics of the usher assembly platform during uropathogenic Escherichia coli P pilus biogenesis. Nature Communications, doi: 10.1038/s41467-021-25522-6.

Guadino, S.J., Huang, H., Jean-Pierre, M., Joshi, P., Beaupre, M., Kempen, C., Wong, H.T., and Kumar, P. (2021). Cutting Edge: Intestinal IL-17A Receptor signaling specifically regulates high-fat diet-mediated, microbiota-driven metabolic disorders. Journal of Immunology, doi: 10.4049/jimmunol.2000986.

Khairallah, C., Chu, T.H., Qiu, Z., Imperato, J.N., Yang, D., and Sheridan, B.S. (2022). The accumulation of Vγ4 T cells with aging is associated with an increased adaptive Vγ4 T cell response after foodborne Listeria monocytogenes infection of mice. Immunity and Ageing 19(1): 19.

Khairallah, C., Bettke, J.A., Gorbatsevych, O., Qiu, Z., Zhang, Y., Cho, K., Kim, K.S., Chu, T.H., Imperato, J.N., Hatano, S., Romanov, G., Yoshikai, Y., Puddington, L., Surh, C.D., Bliska, J.B., van der Velden, A.W.M, and Sheridan, B.S. (2021). A blend of broadly-reactive and pathogen-selected Vγ4Vδ1 T cell receptors confer broad bacterial reactivity of resident memory γδ T cells. Mucosal Immunology, doi: 10.1038/s41385-021-00447-x.

Kim, Y.J., Nomakuchi, T., Papaleonidopoulou, F., Yang, L., Zhang, Q., and Krainer, A.R. (2022). Gene-specific nonsense-mediated mRNA decay targeting for cystic fibrosis therapy. Nature Communications 13(1): 2978.

Lanze, C.E., Zhou, S., and Konopka, J.B. (2021). The Sur7 cytoplasmic C terminus regulates morphogenesis and stress responses in Candida albicans. Molecular Microbiology, doi 10.1111/mmi.14806.

Li, M., Patel, H.V., Cognetta, A.b. 3rd, Smith, T.C., 2nd, Mallick, I., Cavalier, J.R., Previti, M.L., Canaan, S., Aldridge, B.B., Cravatt, B.R., and Seeliger, J.C. (2022). Identification of cell wall synthesis inhibitors active against Mycobacterium tuberculosis by competitive activity-based protein profiling. Cell Chemical Biology 29(5): 883-896.

Lin, X., Gaudino, S.J., Jang, K.K., Bahadur, T., Singh, A., Banerjee, A., Beaupre, M., Chu, T., Wong, H.T., Kim, C.-K., Kempen, C., Axelrad, J., Huang, H, Khalid, S., Shah, Vyom, Eskiocak, O., Parks, O.B., Berisha, A., McAleer, J.P., Good, M., Hoshino, M., Blumberg, R., Bialkowska, A.B., Gaffen, S.L., Kolls, J.K., Yang, V.W., Beyaz, S., Cadwell, K., and Kumar, P. (2022). IL-17RA-signaling in Lgr5+ intestinal epithelial cells induces expression of transcription factor ATOH1 to promote secretory cell lineage commitment. Immunity 55(2): 237-253.

Luperchio, A.M., Jonsson, S.R., and Salamango, D.J. (2022). Evolutionary conservation of PP2A antagonism and G2/M cell cycle arrest in Maedi-Visna virus Vif. Viruses 14(8): 1701.

Marasco, L.E., Dujardin, G., Sousa-Luis, R., Liu, Y.H., Stigliano, J.N., Nomakuchi, T., Proudfoot, N.J., and Krainer, A.R. (2022). Counteracting chromatin effects of a splicing-correcting antisense oligonucleotide improves its therapeutic efficacy in spinal muscular atrophy. Cell 185(12): 2057-2070.

Normile, T.G., Rella, A., and Del Poeta, M. (2021). Cryptococcus neoformanssgl1 vaccination requires either CD4+ or CD8+ T cells for complete host protection. Frontiers in Cellular Infection and Microbiology 11: 739027.

Oliveira, N.K., Bhattacharya, S., Gambhir, R., Joshi, M., and Fries, B.C. (2022). Novel ABC transporter associated with fluconazole resistance in aging of Cryptococcus neoformans. Journal of Fungi 8(7): 677.

Qiu, Z., Qiu, Z., Chu, T.H., and Sheridan, B.S. (2021). TGF-B: Many paths to CD103+ T cell residency. Cells 10(5): 989.

Shieh, J., Chu, T.H., Liu, Y., Kim, J., Ruiz de Sabando, A., Kobayashi, S., Zee, S.Y., Sheridan, B.S., Bialkowska, A.B., and Yang, V.W. (2022). KLF5 protects the intestinal epithelium against Th17 immune response in a murine colitis model. JCI Insight 7(7): e153488.

Silva, B.K.A., Bhattacharya, S., Oliveira, N.K., Savitt, A.G., Zamith-Miranda, D., Nosanchuk, J.D., and Fries, B.C. (2022). Replicative aging remodels the cell wall and is associated with increased intracellular trafficking in human pathogenic yeasts. mBio 13(1): e0019022.

Sohn, S.Y., Hearing, J., Mugavero, J., Kirillov, Varvara, Gorbunova, E., Helminiak, L., Mishra, S., Mackow, E., Hearing, P., Reich, N., and Kim, H.K. (2021). Interferon-lambda intranasal protection and differential sex pathology in a murine model of SARS-CoV-2 infection. mBio 12(6): e0275621.

Snaider, S., Zheng, Y., and Hearing, P. (2022). Rb-E2F-HDAC repressor complexes control interferon-induced repression of adenovirus to promote persistent infection. Journal of Virology 96(11): e0044222.

Wong, H.T., Cheung, V., and Salamango, D.J. (2022). Decoupling SARS-CoV-2 ORF6 localization and interferon antagonism. Journal of Cell Science 135(6): jcs259666.

Yen, W.Y., Stern, K., Mishra, S., Helminiak, L., Sanchez-Vicente, S., and Kim, H.K. (2021). Virulence potential of Rickettsia amblyommatis for spotted fever pathogenesis in mice. Pathogens and Disease 79(5): ftabo24.

Yuen, J.G., Marshilok, A.C., Benziger, P.T., Yan, S., Cello, J., Stackhouse, C.A., Kisslinger, K., Bock, D.C., Takeuchi, E.S., Takeuchi, K.J., Wang, L., Babu, S., Itzkowitz, G., Thanassi, D.G., Knopf, D.A., and Shroyer, K.R., (2022). Dry heat sterilization as a method to recycle N95 respirator masks: the importance of fit. PLoS One 17(1): e0257963.

Abstracts, Conferences/Colloquiums, Invited Talks, Presentations

Conde, J.N., Gorbunova, E., Sanchez-Vincente, S., Mladinich, M.C., Schutt, W.R., Benach, J., and Mackow, E.R. (2021). Powassan virus isolate from Long Island (POWV-LI) persistently infects human brain endothelial cells and is preferentially released basolaterally. American Society for Virology 40th Annual Meeting.

Mladinich, M.C., Conde, J.N., Schutt, W.R., and Mackow, E.R. (2021). Zika virus persistence in primary human brain microvascular endothelial cells is directed by autocrine CCL5-CCR3/5 activation of the ERK1/2 pathway. American Society for Virology 40th Annual Meeting.

Perez, R.D., and Mackow, E.R. (2021). Andes virus competes for host cell caps via its ribonucleoprotein comlex for transcription initiation and translation of viral mRNAs. American Society for Virology 40th Annual Meeting.

Schutt, W.R., Conde, J.N., Mladinich, M.C., and Mackow, E.R. (2021). Zika virus post-transcriptionally regulates IFN expression and alters RNA binding protein activity in primary hBMECs. American Society for Virology 40th Annual Meeting.

Schutt, W.R., Conde, J.N., Mladinich, M.C., and Mackow, E.R. (2021). Zika virus post-transcriptionally regulates IFN expression and alters RNA binding protein activity in primary hBMECs. American Society for Virology 40th Annual Meeting.