John S. Toll Professor
Associate Professor Emeritus
Assistant Dean for Curriculum, Renaissance School of Medicine at Stony Brook University
Basic Sciences Tower, Level 9
Stony Brook Medicine
Stony Brook, NY 11794-8691
Tel: (631) 444-3020
Fax: (631) 444-3424
Email: howard.fleit@stonybrookmedicine.edu
Research Summary:
Howard Fleit is an immunologist whose research focuses on cellular components of the innate immune system. Phagocytic cells, such as macrophages and neutrophils, are members of the innate immune system and have receptors (Fc receptors) on their plasma membranes that bind antibody molecules and thereby bridge the adaptive immune response to cells of the innate immune system. Fleit utilizes biochemical and cell biological techniques to study how different classes of these receptors transduce a signal in the phagocytes to trigger them to release toxic oxygen intermediates, such as superoxide, which can destroy antibody-coated bacteria.
| Education: | |||
| Institution and Location | Degree | Year(s) | Field of Study |
| SUNY at Buffalo, NY | B.A. | 1973 | Biology |
| SUNY at Buffalo, Roswell Park Memorial Institute Division, NY | M.S. | 1974 | Natural Sciences |
| New York University, NY | Ph.D. | 1980 | Cell Biology - Basic Medical Sciences |
|
Positions and Employment: |
|
| 1976-80 | Graduate Student, New York University School of Medicine |
| 1980-83 | Postdoctoral Fellow, The Rockefeller University, NY |
| 1983-89 | Assistant Professor, Department of Pathology, Stony Brook University |
| 1989-present | Associate Professor, Department of Pathology, Stony Brook University |
| 2009-2024 | Vice Chair for Education, Department of Pathology, Stony Brook University |
| 2012-2024 | Assistant Dean for Curriculum, School of Medicine, Stony Brook University |
|
Other Experience and Professional Memberships: |
|
| 1986-present | American Association of Immunologists |
| 1986-present | Society for Leukocyte Biology |
| 1979-present | American Association for the Advancement of Science |
| 2007 | Harvard-Macy Program for Leading Innovations in Health Care and Education |
|
Honors: |
|
| 1981-83 | American Cancer Society Fellowship |
| 1984 | NIH New Investigator Award |
| 1985 | New York State UUP Faculty Development Award |
| 1986 | Catacosinos Young Investigator Award |
| 1986 | Sinsheimer Foundation Scholar Award |
| 1987 | Provost’s Faculty Travel Grant |
| 1994 | New York State UUP Continuing Faculty Development Award |
| 1999, 2002 | New York State UUP Professional Development Award |
| 2008 | Aesculapius Award for Teaching |
Peer Reviewed Publications:
