Lyme Disease Laboratory

About the Laboratory... This laboratory is a division of the Clinical Immunology Laboratory in the Department of Pathology at the Renaissance School of Medicine at Stony Brook University. This laboratory has been performing Lyme disease testing on clinical specimens since 1984. The laboratory is fully licensed and accredited by the NY Department of Health, JCAHO, and CAP. The laboratory performs approximately 36,000 Lyme disease tests on patient specimens per year.

Clinical Laboratory Services

  • Lyme Disease Serologies:
  1. ELISA:  The MTTT (Modified Two-Tiered Test) utilizes two immunoassays, based on multiple B. burgdorferi antigens, that have been cleared by FDA for this use. The MTTT begins with an ELISA immunoassay detecting highly specific VlsE1pepC10 antibodies to B. burgdorferi. Samples negative by this first-tier test do not require further testing. If the 1st tier IgM/IgG immunoassay is positive or equivocal, reflex testing by second tier whole cell sonicate IgM and IgG ELISA’s are performed.
  2. Immunoblot:  A qualitative protein microarray assay for the detection of IgM and IgG antibodies to CDC specific B. Burgdorferi antigens.  It is intended for use in testing of samples which have been found positive or equivocal 1st tier ELISA.
  • Lyme Disease Forms for Printing:
  1. Lyme Results Release Form
  2. Lyme Request Form
  3. Lyme Lab Brochure
  4. CAP Certificate
  5. DOH Certificate 2024-2025

 

  • Specimen Shipping Kits
    U.S. Customers Only: We provide specimen shipping containers free of charge which includes pre-paid shipping - call (631) 444-3824.
    Shipping Request Form

Letter Announcing Immunoblot 09/11/23

Tick Identification Services 

Tick identification will be performed with a prescription from a physician and a fee will be charge.  Please note: Testing for potential tick-borne pathogens is not performed, only identification of the tick species.

Contact Information for Laboratory for the Diagnosis of Lyme Disease:
 
Laboratory (631) 444-3824
Fax: (631) 444-7526
Cathy De Luca, MT (ASCP), Section Supervisor (631) 444-7965
Kenneth O'Sullivan, MS, MT (ASCP), Supervisor/Associate Technical Director (631) 444-2373
Hong Lin Smith-Jones, PhD, Director/Head (631) 444-2240

Laboratory for the Diagnosis of Lyme Disease
University Hospital L3 - 508
101 Nicolls Road
Stony Brook Medicine
Stony Brook, NY 11794-7300

Email: Hong Lin Smith-Jones, PhD
               Kenneth O'Sullivan, MS, MT (ASCP)
               Cathy De Luca, MT(ASCP)