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Key Selected Publications:

  1. Pregosin N, Bronstein R, Mallipattu SK. Recent Advances in Kidney Bioengineering. Frontiers in Pediatrics: Pediatric Nephrology. 2021. (Accepted, In Press).
  2. Gujarati NA, Leonardo AR, Vasquez JM, Guo Y, Frimpong BO, Fozilov E, Revelo MP, Daehn IS, He JC, Bogenhagen D, Mallipattu SK. Loss of Functional SCO2 Attenuates Oxidative Stress in Diabetic Kidney Disease. Diabetes. 2021. Epub 2021/10/28. doi: 10.2337/db21-0316. PubMed PMID: 34702781.
  3. Khan S, Bolotova O, Sahib H, Foster D, Mallipattu SK. Endotoxemia in Critically Ill Patients with SARS-CoV-2 Infection. Critical Care Explorations. Blood Purif. 2021 Aug 20;:1-7. doi: 10.1159/000518230. [Epub ahead of print] PubMed PMID: 34515062; PubMed Central PMCID: PMC8450835.
  4. Pace JA, Bronstein R, Guo Y, Yang Y, Estrada CC, Gujarati N, Salant DJ, Haley J, Bialkowska AB, Yang VW, He JC, Mallipattu SK. Podocyte-specific KLF4 is required to maintain parietal epithelial cell quiescence in the kidney. Sci Adv. 2021;7(36):eabg6600. Epub 2021/09/14. doi: 10.1126/sciadv.abg6600. PubMed PMID: 34516901; PMCID: PMC8442927.
  5. Piret SE, Attallah AA, Gu X, Guo Y, Gujarati NA, Henein J, Zollman A, Hato T, Ma'ayan A, Revelo MP, Dickman KG, Chen CH, Shun CT, Rosenquist TA, He JC, Mallipattu SK. Loss of proximal tubular transcription factor Kruppel-like factor 15 exacerbates kidney injury through loss of fatty acid oxidation. Kidney international. 2021. Epub 2021/10/12. doi: 10.1016/j.kint.2021.08.031. PubMed PMID: 34634362.
  6. Piret SE, Guo Y, Attallah AA, Horne SJ, Zollman A, Owusu D, Henein J, Sidorenko VS, Revelo MP, Hato T, Ma'ayan A, He JC, Mallipattu SK. Kruppel-like factor 6-mediated loss of BCAA catabolism contributes to kidney injury in mice and humans. Proc Natl Acad Sci U S A. 2021;118(23). Epub 2021/06/03. doi: 10.1073/pnas.2024414118. PubMed PMID: 34074766; PMCID: PMC8201852.
  7. Bolotova O, Yoo J, Chaudhri I, Marcos LA, Sahib H, Koraishy FM, Skopicki H, Ahmad S, Mallipattu SK. Safety, Tolerability, and Efficacy of Losartan in Patients Hospitalized with SARS-CoV-2 Infection: A Feasibility Study. PlosOne (2020). Dec 30;15(12):e0244708. doi: 10.1371/journal.pone.0244708. PMID: 33378401.
  8. Gujarati NA, Vasquez JA, Bogenhagen DF, Mallipattu SK. The Complicated Role of the Mitochondria in the Podocyte. American Journal of Physiology-Renal Physiology (2020). doi: 10.1152/ajprenal.00393.2020. Epub 2020 Oct 19. PMID: 33073585.
  9. Chaudhri I, Koraishy FM, Bolotova O, Yoo J, Marcos LA, Taub E, Sahib H, Bloom M, Ahmad S, Skopicki H, Mallipattu SK. Outcomes associated with the use of RAAS Blockade in hospitalized patients with SARS-CoV-2 infection. Kidney360 (2020). doi:10.34067/KID.0003792020. PMID: 33345195.
  10. Kravets I, Mallipattu SK. The Role of Podocytes and Podocyte-Associated Biomarkers in Diagnosis and Treatment of Diabetic Kidney Disease. Journal of Endocrine Society (2020). doi: 10.1210/jendso/bvaa029. PubMed PMID: 32232184.
  11. Kott J, Reichek N, Butler J, Arbeit L, Mallipattu SK. Cardiac Imaging in Dialysis Patients. Kidney Medicine (2020). doi:10.1016/j.xkme.2020.05.010.
  12. Stony Brook COVID-19 Research Consortium (Mallipattu SK). Geospatial Distribution and Predictors of Mortality in Hospitalized Patients with COVID-19: A Cohort Study. Open Forum Infectious Diseases (2020). Sep 14;7(10):ofaa436. doi: 10.1093/ofid/ofaa436. PMID: 33117852. *Corresponding author in this consortium manuscript
  13. Pace J, Das B, He JC, Mallipattu SK. Targeting STAT3 Signaling in Kidney Disease. American journal of physiology Renal physiology (2019). doi: 10.1152/ajprenal.00034.2019. Epub 2019 Apr 3. PMID:30943069.
  14. Estrada CC, Maldonado A, Mallipattu SK. Therapeutic Inhibition of VEGF Signaling and Associated Nephrotoxicities. Journal of the American Society of Nephrology (2019). doi: 10.1681/ASN.2018080853. PubMed PMID: 30642877.
  15. Horne SJ, Vasquez J, Guo Y, Ly V, Piret S, Leonardo A, Ling J, Revelo MP, Bogenhagen D, Yang VW, He JC, Mallipattu SK. Podocyte-Specific Loss of Kruppel-Like Factor 6 Increases Mitochondrial Injury in Diabetic Kidney Disease. Diabetes (2018). doi: 10.2337/db17-0958. PubMed PMID: 30115650.
  16. Guo Y, Pace J, Li Z, Ma'ayan A, Wang Z, Revelo MP, Chen E, Gu X, Attalah A, Yang Y, Estrada C, Yang VW, He JC, Mallipattu SK. Podocyte-Specific Induction of Kruppel-Like Factor 15 Restores Differentiation Markers and Attenuates Kidney Injury in Proteinuric Kidney Disease. Journal of the American Society of Nephrology (2018). doi: 10.1681/ASN.2018030324. PubMed PMID: 30143559. 
  17. Estrada CC, Paladugu P, Guo Y, Pace J, Revelo MP, Salant DJ, Shankland SJ, D'Agati VD, Mehrotra A, Cardona S, Bialkowska AB, Yang VW, He JC, Mallipattu SK. Kruppel-like factor 4 is a negative regulator of STAT3-induced glomerular epithelial cell proliferation. Journal of Clinical Investigation Insight (2018). doi: 10.1172/jci.insight.98214. PubMed PMID: 29925693. 
  18. Gu X, Mallipattu SK, Guo Y, Revelo MP, Pace J, Miller T, Gao X, Jain MK, Bialkowska AB, Yang VW, He JC, and Mei C. The loss of Krüppel-like factor 15 in Foxd1+ stromal cells exacerbates kidney fibrosis. Kidney International (2017). doi: 10.1016/j.kint.2017.03.037. PubMed PMID: 28651950. *Corresponding and co-first author
  19. Bialkowska AB, Yang VW, Mallipattu SK. Kruppel-like factors in mammalian stem cells and development. Development (2017). doi: 10.1242/dev.145441. PubMed PMID: 28246209.
  20. Mallipattu SK, Estrada CC, He JC. The critical role of Krüppel-like factors in kidney disease. American journal of physiology Renal physiology (2016). doi: 10.1152/ajprenal.00550.2016. PubMed PMID: 27852611. 
  21. Mallipattu SK, He JC. The podocyte as a direct target for treatment of glomerular disease? American journal of physiology Renal physiology (2016). doi: 10.1152/ajprenal.00184.2016. PubMed PMID: 27097894.
  22. Mallipattu SK*, Guo Y, Revelo MP, Roa-Pena L, Miller T, Ling J,et al. Krüppel-like Factor 15 Mediates Glucocorticoid-Induced Restoration of Podocyte Differentiation Markers. Journal of the American Society of Nephrology (2016). doi: 10.1681/ASN.2015060672. PubMed PMID: 27288011.           
  23. Mallipattu SK, He JC. KLF6: a mitochondrial regulator in the kidney. Oncotarget (2015). doi: 10.18632/oncotarget.4647. Pubmed PMID: 26158635.
  24. Mallipattu SK, He JC. The Beneficial Role of Retinoids in Glomerular Disease. Frontiers in Medicine (2015). 10.3389/fmed.2015.00016.
  25. Mallipattu SK, Horne SJ, D'Agati V, Narla G, Liu R, Frohman MA, et al. Kruppel-like factor 6 regulates mitochondrial function in the kidney. The Journal of clinical investigation (2015). doi: 10.1172/JCI77084. PubMed PMID: 25689250. 
  26. Zhong F, Chen H, Wei C, Zhang W, Li Z, Jain MK, Mallipattu SK, He JC. Reduced Kruppel-like factor 2 expression may aggravate the endothelial injury of diabetic nephropathy. Kidney international (2015). doi: 10.1038/ki.2014.286. PubMed PMID: 25185079; PubMed Central PMCID: PMC4312548.
  27. Mallipattu SK, Salem F, Wyatt CM. The changing epidemiology of HIV-related chronic kidney disease in the era of antiretroviral therapy. Kidney international (2014). doi: 10.1038/ki.2014.44. PubMed PMID: 24573317.
  28. Mallipattu SK, Uribarri J. Advanced glycation end product accumulation: a new enemy to target in chronic kidney disease? Current opinion in nephrology and hypertension (2014). doi: 10.1097/MNH.0000000000000062. PubMed PMID: 25160075.
  29. Mallipattu SK, Gallagher EJ, LeRoith D, Liu R, Mehrotra A, Horne SJ, et al. Diabetic nephropathy in a nonobese mouse model of type 2 diabetes mellitus. American journal of physiology Renal physiology (2014). doi: 10.1152/ajprenal.00597.2013. PubMed PMID: 24598803.
  30. Gu L, Dai Y, Xu J, Mallipattu SK, Kaufman L, Klotman PE, et al. Deletion of podocyte STAT3 mitigates the entire spectrum of HIV-1-associated nephropathy. AIDS (London, England) (2013). doi: 10.1097/QAD.0b013e32835f1ea1. PubMed PMID: 23343908.
  31. Mallipattu SK, He JC. A new mechanism for albuminuria-induced podocyte injury. Journal of the American Society of Nephrology: JASN (2013). doi: 10.1681/ASN.2013070714. PubMed PMID: 23990672.
  32. Mallipattu SK, Liu R, Zhong Y, Chen EY, D'Agati V, Kaufman L, et al. Expression of HIV transgene aggravates kidney injury in diabetic mice. Kidney international (2013). doi: 10.1038/ki.2012.445. PubMed PMID: 23325078.
  33. Mallipattu SK, Wyatt CM, He JC. The New Epidemiology of HIV-Related Kidney Disease. Journal of AIDS & clinical research (2012). doi: 10.4172/2155-6113.S4-001. PubMed PMID: 25309811.
  34. Mallipattu SK, Liu R, Zheng F, Narla G, Ma'ayan A, Dikman S, et al. Kruppel-like factor 15 (KLF15) is a key regulator of podocyte differentiation. The Journal of biological chemistry (2012). doi: 10.1074/jbc.M112.345983. PubMed PMID: 22493483.