Publications

Bialkowska PubMed: https://www.ncbi.nlm.nih.gov/myncbi/agnieszka.bialkowska.1/bibliography/public/?sortby=pubDate&sdirection=descending

Giarrizzo M, LaComb JF, Patel HR, Reddy RG, Haley JD, Graves LM, Iwanowicz EJ, Bialkowska AB. TR-107, An Agonist of Caseinolytic Peptidase Proteolytic Subunit, Disrupts Mitochondrial Metabolism and Inhibits the Growth of Human Colorectal Cancer Cells. Mol Cancer Ther. 2024 Sep 5;. doi: 10.1158/1535-7163.MCT-24-0170. [Epub ahead of print] PubMed PMID: 39233476; NIHMSID:NIHMS2022564.

M Swamynathan M, Mathew G, Aziz A, Gordon C, Hillowe A, Wang H, Jhaveri A, Kendall J, Cox H, Giarrizzo M, Azabdaftari G, Rizzo RC, Diermeier SD, Ojima I, Bialkowska AB, Kaczocha M, Trotman LC. FABP5 Inhibition against PTEN-Mutant Therapy Resistant Prostate Cancer. Cancers (Basel). 2023 Dec 21;16(1). doi: 10.3390/cancers16010060. PubMed PMID: 38201488; PubMed Central PMCID: PMC10871093.

Alavi M, Mejia-Bautista A, Tang M, Bandovic J, Rosenberg AZ, Bialkowska AB. Krüppel-like Factor 5 Plays an Important Role in the Pathogenesis of Chronic Pancreatitis. Cancers (Basel). 2023 Nov 15;15(22). doi: 10.3390/cancers15225427. PubMed PMID: 38001687; PubMed Central PMCID: PMC10670257.

Ingle K, LaComb JF, Graves LM, Baines AT, Bialkowska AB. AUM302, a novel triple kinase PIM/PI3K/mTOR inhibitor, is a potent in vitro pancreatic cancer growth inhibitor. PLoS One. 2023;18(11):e0294065. doi: 10.1371/journal.pone.0294065. eCollection 2023. PubMed PMID: 37943821; PubMed Central PMCID: PMC10635512.

Hillowe A, Gordon C, Wang L, Rizzo RC, Trotman LC, Ojima I, Bialkowska A, Kaczocha M. Fatty acid binding protein 5 regulates docetaxel sensitivity in taxane-resistant prostate cancer cells. PLoS One. 2023;18(10):e0292483. doi: 10.1371/journal.pone.0292483. eCollection 2023. PubMed PMID: 37796964; PubMed Central PMCID: PMC10553314.

Kobayashi S, Sullivan C, Bialkowska AB, Saltz JH, Yang VW. Computational immunohistochemical mapping adds immune context to histological phenotypes in mouse models of colitis. Sci Rep. 2023 Sep 1;13(1):14386. doi: 10.1038/s41598-023-41574-8. PubMed PMID: 37658187; PubMed Central PMCID: PMC10474139.

Orzechowska-Licari EJ, Bialkowska AB, Yang VW. Sonic Hedgehog and WNT Signaling Regulate a Positive Feedback Loop Between Intestinal Epithelial and Stromal Cells to Promote Epithelial Regeneration. Cell Mol Gastroenterol Hepatol. 2023;16(4):607-642. doi: 10.1016/j.jcmgh.2023.07.004. Epub 2023 Jul 20. PubMed PMID: 37481204; PubMed Central PMCID: PMC10470419.

Wiley MB, Mehrotra K, Bauer J, Yazici C, Bialkowska AB, Jung B. Acute Pancreatitis: Current Clinical Approaches, Molecular Pathophysiology, and Potential Therapeutics. Pancreas. 2023 Jul 1;52(6):e335-e343. doi: 10.1097/MPA.0000000000002259. Review. PubMed PMID: 38127317.

Giarrizzo M, LaComb JF, Bialkowska AB. The Role of Krüppel-like Factors in Pancreatic Physiology and Pathophysiology. Int J Mol Sci. 2023 May 11;24(10). doi: 10.3390/ijms24108589. Review. PubMed PMID: 37239940; PubMed Central PMCID: PMC10218095.

Lee E, Cheung J, Bialkowska AB. Krüppel-like Factors 4 and 5 in Colorectal Tumorigenesis. Cancers (Basel). 2023 Apr 24;15(9). doi: 10.3390/cancers15092430. Review. PubMed PMID: 37173904; PubMed Central PMCID: PMC10177156.

Almanzar VMD, Shah K, LaComb JF, Mojumdar A, Patel HR, Cheung J, Tang M, Ju J, Bialkowska AB. 5-FU-miR-15a Inhibits Activation of Pancreatic Stellate Cells by Reducing YAP1 and BCL-2 Levels In Vitro. Int J Mol Sci. 2023 Feb 16;24(4). doi: 10.3390/ijms24043954. PubMed PMID: 36835366; PubMed Central PMCID: PMC9961454.

Patel HR, Diaz Almanzar VM, LaComb JF, Ju J, Bialkowska AB. The Role of MicroRNAs in Pancreatitis Development and Progression. Int J Mol Sci. 2023 Jan 5;24(2). doi: 10.3390/ijms24021057. Review. PubMed PMID: 36674571; PubMed Central PMCID: PMC9862468.

Komatsu DE, Uddin SMZ, Gordon C, Kanjiya MP, Bogdan D, Achonu J, DiBua A, Iftikhar H, Ackermann A, Shah RJ, Shieh J, Bialkowska AB, Kaczocha M. Acute postoperative pain and dorsal root ganglia transcriptomic signatures following total knee arthroplasty (TKA) in rats: An experimental study. PLoS One. 2022;17(12):e0278632. doi: 10.1371/journal.pone.0278632. eCollection 2022. PubMed PMID: 36473007; PubMed Central PMCID: PMC9725137.

Orzechowska-Licari EJ, LaComb JF, Mojumdar A, Bialkowska AB. SP and KLF Transcription Factors in Cancer Metabolism. Int J Mol Sci. 2022 Sep 1;23(17). doi: 10.3390/ijms23179956. Review. PubMed PMID: 36077352; PubMed Central PMCID: PMC9456310.

Kobayashi S, Shieh J, Ruiz de Sabando A, Kim J, Liu Y, Zee SY, Prasanna P, Bialkowska AB, Saltz JH, Yang VW. Deep learning-based approach to the characterization and quantification of histopathology in mouse models of colitis. PLoS One. 2022;17(8):e0268954. doi: 10.1371/journal.pone.0268954. eCollection 2022. PubMed PMID: 36037173; PubMed Central PMCID: PMC9423669.

Orzechowska-Licari EJ, LaComb JF, Giarrizzo M, Yang VW, Bialkowska AB. Intestinal Epithelial Regeneration in Response to Ionizing Irradiation. J Vis Exp. 2022 Jul 27;(185). doi: 10.3791/64028. PubMed PMID: 35969101; PubMed Central PMCID: PMC9631267.

Shieh J, Chu TH, Liu Y, Kim J, Ruiz de Sabando A, Kobayashi S, Zee SY, Sheridan BS, Bialkowska AB, Yang VW. KLF5 protects the intestinal epithelium against Th17 immune response in a murine colitis model. JCI Insight. 2022 Apr 8;7(7). doi: 10.1172/jci.insight.153488. PubMed PMID: 35393949; PubMed Central PMCID: PMC9057631.

Lin X, Gaudino SJ, Jang KK, Bahadur T, Singh A, Banerjee A, Beaupre M, Chu T, Wong HT, Kim CK, Kempen C, Axelrad J, Huang H, Khalid S, Shah V, Eskiocak O, Parks OB, Berisha A, McAleer JP, Good M, Hoshino M, Blumberg R, Bialkowska AB, Gaffen SL, Kolls JK, Yang VW, Beyaz S, Cadwell K, Kumar P. IL-17RA-signaling in Lgr5(+) intestinal stem cells induces expression of transcription factor ATOH1 to promote secretory cell lineage commitment. Immunity. 2022 Feb 8;55(2):237-253.e8. doi: 10.1016/j.immuni.2021.12.016. Epub 2022 Jan 25. PubMed PMID: 35081371; PubMed Central PMCID: PMC8895883.

Pace JA, Bronstein R, Guo Y, Yang Y, Estrada CC, Gujarati N, Salant DJ, Haley J, Bialkowska AB, Yang VW, He JC, Mallipattu SK. Podocyte-specific KLF4 is required to maintain parietal epithelial cell quiescence in the kidney. Sci Adv. 2021 Sep 3;7(36):eabg6600. doi: 10.1126/sciadv.abg6600. Epub 2021 Sep 3. PubMed PMID: 34516901; PubMed Central PMCID: PMC8442927.

Hoffman M, Palioura D, Kyriazis ID, Cimini M, Badolia R, Rajan S, Gao E, Nikolaidis N, Schulze PC, Goldberg IJ, Kishore R, Yang VW, Bannister TD, Bialkowska AB, Selzman CH, Drakos SG, Drosatos K. Cardiomyocyte Krüppel-Like Factor 5 Promotes De Novo Ceramide Biosynthesis and Contributes to Eccentric Remodeling in Ischemic Cardiomyopathy. Circulation. 2021 Mar 16;143(11):1139-1156. doi: 10.1161/CIRCULATIONAHA.120.047420. Epub 2021 Jan 12. PubMed PMID: 33430631; PubMed Central PMCID: PMC7965352.

Gaudino SJ, Beaupre M, Lin X, Joshi P, Rathi S, McLaughlin PA, Kempen C, Mehta N, Eskiocak O, Yueh B, Blumberg RS, van der Velden AWM, Shroyer KR, Bialkowska AB, Beyaz S, Kumar P. IL-22 receptor signaling in Paneth cells is critical for their maturation, microbiota colonization, Th17-related immune responses, and anti-Salmonella immunity. Mucosal Immunol. 2021 Mar;14(2):389-401. doi: 10.1038/s41385-020-00348-5. Epub 2020 Oct 15. PubMed PMID: 33060802; PubMed Central PMCID: PMC7946635.

Kyriazis ID, Hoffman M, Gaignebet L, Lucchese AM, Markopoulou E, Palioura D, Wang C, Bannister TD, Christofidou-Solomidou M, Oka SI, Sadoshima J, Koch WJ, Goldberg IJ, Yang VW, Bialkowska AB, Kararigas G, Drosatos K. KLF5 Is Induced by FOXO1 and Causes Oxidative Stress and Diabetic Cardiomyopathy. Circ Res. 2021 Feb 5;128(3):335-357. doi: 10.1161/CIRCRESAHA.120.316738. Epub 2020 Dec 2. PubMed PMID: 33539225; PubMed Central PMCID: PMC7870005.

Katano T, Bialkowska AB, Yang VW. KLF4 Regulates Goblet Cell Differentiation in BMI1(+) Reserve Intestinal Stem Cell Lineage during Homeostasis. Int J Stem Cells. 2020 Nov 30;13(3):424-431. doi: 10.15283/ijsc20048. PubMed PMID: 32840226; PubMed Central PMCID: PMC7691855.

Orzechowska EJ, Katano T, Bialkowska AB, Yang VW. Interplay among p21(Waf1/Cip1), MUSASHI-1 and Krüppel-like factor 4 in activation of Bmi1-Cre(ER) reserve intestinal stem cells after gamma radiation-induced injury. Sci Rep. 2020 Oct 27;10(1):18300. doi: 10.1038/s41598-020-75171-w. PubMed PMID: 33110120; PubMed Central PMCID: PMC7591575.