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Research Assistant Professor, Email: emmeline.ayers@stonybrookmedicine.edu Location: Stony Brook University,101 Nicolls Road, Stony Brook, NY 11794 |
Area of ResearchEpidemiology of aging; Gait; Clinical trial Management. |
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Education and Training |
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Education:
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Bachelor of Arts, Psychology |
The College of Wooster, Wooster, OH |
May 2009 | |
| Master of Public Health, Health Policy and Management | Rollins School of Public Health, Emory University, Atlanta, GA | May 2012 | |
| Professional Interests: |
I am a Research Assistant Professor in the Division of Cognitive and Sensorimotor Aging. I'm involved in the coordination of many of the ongoing research projects in the division, which include several clinical trials, longitudinal studies and a multi-country consortium to study a gait-based pre-dementia syndrome. My research interests include study design and data management and harmonization of large datasets for epidemiological studies. My current projects focus on understanding clinical markers and preventative strategies that can delay the onset of common adverse events in aging including mobility disability, frailty, falls and cognitive decline. My most recent publications focus on the examination of a newly described pre-dementia syndrome, Motoric Cognitive Risk syndrome (MCR). MCR is characterized by the presence of cognitive complaints and slow gait, provides a simple and accessible clinical method to assess individuals at risk of converting to dementia. Together with an international group of collaborators, we conducted a global validation study of this syndrome using data from 22 studies including over 26,000 participants. In subsequent studies we have also established MCR as a risk factor for non-cognitive outcomes including mortality and falls. |
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| Selected Publications: |
Verghese J, Chalmer R, Stimmel M, Weiss E, Zwerling J, Malik R, Rasekh D, Ansari A, Corriveau RA, Ehrlich AR, Wang C, Ayers E. Non-literacy biased, culturally fair cognitive detection tool in primary care patients with cognitive concerns: a randomized controlled trial. Nat Med. 2024 Aug;30(8):2356-2361. doi: 10.1038/s41591-024-03012-8. Epub 2024 Jun 4. PubMed PMID: 38834847; PubMed Central PMCID: PMC11333278. Ayers E, Wang C, Verghese J. Validation of a "subjective motoric cognitive risk syndrome" screening tool for motoric cognitive risk syndrome-A prospective cohort study. Eur J Neurol. 2022 Oct;29(10):2925-2933. doi: 10.1111/ene.15476. Epub 2022 Jul 9. PubMed PMID: 35748730; PubMed Central PMCID: PMC9875832. Kravatz NL, Ayers E, Bennett DA, Verghese J. Olfactory Dysfunction and Incidence of Motoric Cognitive Risk Syndrome: A Prospective Clinical-Pathologic Study. Neurology. 2022 Oct 24;99(17):e1886-e1896. doi: 10.1212/WNL.0000000000201030. PMID: 36240083; PMCID: PMC9620808. Ayers E, Gulley E, Verghese J. The Effect of Personality Traits on Risk of Incident Pre-dementia Syndromes. J Am Geriatr Soc. 2020 Jul;68(7):1554-1559. doi: 10.1111/jgs.16424. Epub 2020 Jun 2. PubMed PMID: 32488931; PubMed Central PMCID: PMC7363540. Verghese J, Mahoney JR, Ayers E, Ambrose A, Wang C, Holtzer R. Computerised cognitive remediation to enhance mobility in older adults: a single-blind, single-centre, randomised trial. The Lancet Healthy Longevity. 2021 Sep 1;2(9):e571-9. PMID: 34522910 PMCID: PMC8437150. Verghese J, Ayers E, Sathyan S, Lipton RB, Milman S, Barzilai N, Wang C. Trajectories of frailty in aging: Prospective cohort study. PLoS One. 2021 Jul 12;16(7):e0253976. doi: 10.1371/journal.pone.0253976. PMID: 34252094; PMCID: PMC8274857. Gulley E, Verghese J, Blumen HM, Ayers E, Wang C, Portenoy RK, Zwerling JL, Weiss E, Knotkova H. Neurostimulation for cognitive enhancement in Alzheimer's disease (the NICE-AD study): a randomized clinical trial. Neurodegener Dis Manag. 2021 Jul 9. doi: 10.2217/nmt-2020-0061. Epub ahead of print. PMID: 34240627. Rodríguez D, Ayers E, Weiss EF, Verghese J. Cross-Cultural Comparisons of Subjective Cognitive Complaints in a Diverse Primary Care Population. J Alzheimers Dis. 2021;81(2):545-555. doi: 10.3233/JAD-201399. PMID: 33814436; PMCID: PMC8190561. Blumen HM, Ayers E, Wang C, Ambrose AF, Jayakody O, Verghese J. Randomized Controlled Trial of Social Ballroom Dancing and Treadmill Walking: Preliminary Findings on Executive Function and Neuroplasticity From Dementia-at-Risk Older Adults. J Aging Phys Act. 2023 Aug 1;31(4):589-599. doi: 10.1123/japa.2022-0176. Print 2023 Aug 1. PubMed PMID: 36516851; PubMed Central PMCID: PMC10264554. Verghese J, Wang C, Bennett DA, Lipton RB, Katz MJ, Ayers E. Motoric Cognitive Risk Syndrome and predictors of transition to dementia: Multi-center Study. Alzheimer’s and Dementia. 2019 Jul;15(7):870-877. PMID: 31164315. Ayers E, Verghese J. Motoric cognitive risk syndrome and risk of mortality in older adults. Alzheimer’s and Dementia. 2016; 12(5): 556-64. PMID: 26545790. Complete List of Published Work available in SciENcv https://www.ncbi.nlm.nih.gov/myncbi/emmeline.ayers.1/bibliography/public/Other Links |
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