Marissa Lindner

Marissa Lindner


 


B.S., Stony Brook University
Advisor: Erich Mackow
Email: Marissa.Lindner@stonybrook.edu

 

Research InterestsMy research interests are in viral pathogenesis and cellular molecular mechanisms of emerging diseases. My undergraduate research focused on antibodies as a therapeutic for carbapenem-resistant Klebsiella pneumoniae and the development of a capsular polysaccharide vaccination against CR-Kp. My undergraduate thesis investigated the binding of mAb24D11 against various isolates of CR-Kp. 
Awards

2025 Outstanding Poster Award, Department of Microbiology & Immunology Retreat, Stony Brook University, Stony Brook, NY

Distinguished Service Award; 2025 Department of Microbiology and Immunology, Stony Brook University, Stony Brook, NY

2026 American Society for Virology Travel Award

Publications

Lindner MR, Gorbunova EE, de Souza MRM, Himmler GE, Kim HK, Mackow ER.0.Powassan virus LB neuroinvasion and lethality are determined by envelope protein domain III residues. J Virol0:e00963-26. https://doi.org/10.1128/jvi.00963-26

de Souza MRM, Lindner MR, Mladinich-Valenti M, Gorbunova EE, Kirillov V, Byrne AG, Laird AY, Finnerty CE, Ikeda P, Vorkas CK, Kaur R, Gomes YCP, Chatel-Chaix L, Kim HK, Mackow ER.0.Single-cell analysis of Powassan virus-infected brains reveals age-dependent neuroinflammatory crosstalk and progressive Alzheimer’s-like APP/Aβ accumulation. mBio0:e01294-26. https://doi.org/10.1128/mbio.01294-26

Himmler GE, Mladinich MC, Conde JN, Gorbunova EE, Lindner MR, Kim HK, Mackow ER. Passage-attenuated Powassan virus LI9P protects mice from lethal LI9 challenge and links envelope residue D308 to neurovirulence. mBio. 2025 Apr 9;16(4):e0006525. doi: 10.1128/mbio.00065-25.

Laird, A. Y., Kirillov, V., Gorbunova, E. E., Vostrov, A., Rochlin, G., Finnerty, C. E., Byrne, A. G., Ikeda, P., Matos, R., Lindner, M. R., Kim, H. K., & Mackow, E. R. (2026). Fluorescent Powassan Reporter Viruses Infect Neuron, Astrocyte and Microglial Cell Lines Independent of Attenuating D308N Envelope Protein Modification. Viruses, 18(7), 768. https://doi.org/10.3390/v18070768

Glicksberg, J., Sajib, M.I., Sankaran, S., Lindner, M., Mui, J., Boniche-Alfaro, C., and Fries, B.C. (2023). Epidemiology of ESBL Klebsiella pneumoniae clonal group 307 in Stony Brook, NY. Open Forum Infectious Diseases 10, Issue Supplement_2. https://doi.org/10.1093/ofid/ofad500.343

Presentations

Lindner MR, Gorbunova EE, Himmler GE, Marcos RM, Riera G, Kim HK, Mackow ER. (2025). Reverse Genetic Attenuation of Powassan Virus LB is Conferred by Mutating Envelope Protein Domain III Residues. Talk presented at: American Society for Virology 44th annual meeting; 2025 July 16; Montreal QC Canada.

Lindner MR, Gorbunova EE, Himmler GE, Marcos RM, Riera G, Kim HK, Mackow ER. (2025). Envelope Domain III residues determine Powassan VIrus LB neuroinvasion and lethality. Talk presented at: American Society for Virology 45th annual meeting; 2026 July 27; Minneapolis MN United States.