Marcos LA, Vorkas CK, Mann I, Garry E, Lamba P, Pham SK, Spector R, Papamanoli A, Krivacsy S, Lum M, Zahra A, Hou W, Spitzer ED. Reduced Cholesterol Levels during Acute Human Babesiosis. Pathogens. 2023 Apr 18;12(4). doi: 10.3390/pathogens12040613. PubMed PMID: 37111499; PubMed Central PMCID: PMC10144092.
T-Cells target TB
Atul Pradhan 1 2, Charles Kyriakos Vorkas 1 2
Single-Cell Transcriptional Profiling Reveals Signatures of Helper, Effector, and Regulatory MAIT Cells during Homeostasis and Activation.
Vorkas CK, Krishna C, Li K, Aubé J, Fitzgerald DW, Mazutis L, Leslie CS, Glickman MS.
J Immunol. 2022 Mar 1;208(5):1042-1056. doi: 10.4049/jimmunol.2100522. Epub 2022 Feb 11.
PMID: 35149530
Metabolic and Immune Markers for Precise Monitoring of COVID-19 Severity and Treatment.
Rendeiro AF, Vorkas CK, Krumsiek J, Singh HK, Kapadia SN, Cappelli LV, Cacciapuoti MT, Inghirami G,
Elemento O, Salvatore M.
Front Immunol. 2022 Jan 12;12:809937. doi: 10.3389/fimmu.2021.809937. eCollection 2021.
PMID: 35095900
Transcriptomic Biomarkers for Tuberculosis: Validation of NPC2 as a Single mRNA Biomarker to Diagnose TB, Predict Disease Progression, and Monitor Treatment Response.
de Araujo LS, Ribeiro-Alves M, Wipperman MF, Vorkas CK, Pessler F, Saad MHF.
Cells. 2021 Oct 9;10(10):2704. doi: 10.3390/cells10102704.
PMID: 34685683
Gastrointestinal microbiota composition predicts peripheral inflammatory state during treatment of human tuberculosis.
Wipperman MF, Bhattarai SK, Vorkas CK, Maringati VS, Taur Y, Mathurin L, McAulay K, Vilbrun SC, Francois D, Bean J, Walsh KF, Nathan C, Fitzgerald DW, Glickman MS, Bucci V.
Nat Commun. 2021 Feb 18;12(1):1141. doi: 10.1038/s41467-021-21475-y.
PMID: 33602926
Profiling of immune dysfunction in COVID-19 patients allows early prediction of disease progression.
Rendeiro AF, Casano J, Vorkas CK, Singh H, Morales A, DeSimone RA, Ellsworth GB, Soave R, Kapadia SN, Saito K, Brown CD, Hsu J, Kyriakides C, Chiu S, Cappelli LV, Cacciapuoti MT, Tam W, Galluzzi L, Simonson PD, Elemento O, Salvatore M,
Inghirami G.
Life Sci Alliance. 2020 Dec 24;4(2):e202000955. doi: 10.26508/lsa.202000955. Print 2021 Feb.
PMID: 33361110
Efficient 5-OP-RU-Induced Enrichment of Mucosa-Associated Invariant T Cells in the Murine Lung Does Not Enhance Control of Aerosol Mycobacterium tuberculosis Infection.
Vorkas CK, Levy O, Skular M, Li K, Aubé J, Glickman MS.
Infect Immun. 2020 Dec 15;89(1):e00524-20. doi: 10.1128/IAI.00524-20. Print 2020 Dec 15.
PMID: 33077620
Longitudinal immune profiling of mild and severe COVID-19 reveals innate and adaptive immune dysfunction and provides an early prediction tool for clinical progression.
Rendeiro AF, Casano J, Vorkas CK, Singh H, Morales A, DeSimone RA, Ellsworth GB, Soave R, Kapadia SN, Saito K, Brown CD, Hsu J, Kyriakides C, Chui S, Cappelli L, Cacciapuoti MT, Tam W, Galluzzi L, Simonson PD, Elemento O, Salvatore M,
Inghirami G.
medRxiv. 2020 Sep 9:2020.09.08.20189092. doi: 10.1101/2020.09.08.20189092. Preprint.
PMID: 32935114
Mucosal-associated invariant and γδ T cell subsets respond to initial Mycobacterium tuberculosis infection.
Vorkas CK, Wipperman MF, Li K, Bean J, Bhattarai SK, Adamow M, Wong P, Aubé J, Juste MAJ, Bucci V, Fitzgerald DW, Glickman MS.
JCI Insight. 2018 Oct 4;3(19):e121899. doi: 10.1172/jci.insight.121899.
PMID: 30282828
Synthesis, stabilization, and characterization of the MR1 ligand precursor 5-amino-6-D-ribitylaminouracil (5-A-RU).
Li K, Vorkas CK, Chaudhry A, Bell DL, Willis RA, Rudensky A, Altman JD, Glickman MS, Aubé J.
PLoS One. 2018 Feb 5;13(2):e0191837. doi: 10.1371/journal.pone.0191837. eCollection 2018.
PMID: 29401462
Altered mental status is an indicator of mortality and associated with both infectious and non-communicable disease in Lilongwe, Malawi.
Harrington B, Vorkas CK, Kanyama C, Ngoma J, Hoffman I, Hosseinipour MC.
Trop Doct. 2015 Jul;45(3):164-7. doi: 10.1177/0049475515577024. Epub 2015 Mar 29.
PMID: 25824564
Practices to improve identification of adult antiretroviral therapy failure at the Lighthouse Trust clinic in Lilongwe, Malawi.
Vorkas CK, Tweya H, Mzinganjira D, Dickie G, Weigel R, Phiri S, Hosseinipour MC.
Trop Med Int Health. 2012 Feb;17(2):169-76. doi: 10.1111/j.1365-3156.2011.02912.x. Epub 2011 Nov 1.
PMID: 22039960
Testosterone replacement therapy and polycythemia in HIV-infected patients.
Vorkas CK, Vaamonde CM, Glesby MJ.
AIDS. 2012 Jan 14;26(2):243-5. doi: 10.1097/QAD.0b013e32834db446.
PMID: 22008652
HIV and tuberculosis in Russia and eastern Europe: sounding the alarm.
Vorkas CK, van der Horst C.
AIDS. 2009 Nov 27;23(18):2533-4. doi: 10.1097/QAD.0b013e328332d5f8.
PMID: 19841570
Postictal psychosis in partial epilepsy: a case-control study.
Alper K, Kuzniecky R, Carlson C, Barr WB, Vorkas CK, Patel JG, Carrelli AL, Starner K, Flom PL, Devinsky O.
Ann Neurol. 2008 May;63(5):602-10. doi: 10.1002/ana.21341.
PMID: 18481288
Epilepsy and dental procedures. A review.
Vorkas CK, Gopinathan MK, Singh A, Devinsky O, Lin LM, Rosenberg PA.
NY State Dent J. 2008 Mar;74(2):39-43.
PMID: 18450188 Review.
