Patent: Small Molecules for Cancer Therapy that Reduce the Expression of Transcription Factors KLF5 and EGR-1

Dear Department of Medicine Community:

Congratulations to Dr. Vincent Yang, Simons Chair of Medicine, and Dr. Agnieszka Bialkowska, Associate Professor of Medicine, Division of Gastroenterology and Hepatology at Stony Brook Medicine on their recently issued patent, awarded by The National Institutes of Health.
"Small Molecules for Cancer Therapy that Reduce the Expression of Transcription Factors KLF5 and EGR-1"

Summary: "The present disclosure relates, in one embodiment, to a new small molecule lead, designated SR18662, that efficiently inhibits the growth of CRC cells both in vitro and in vivo and that reduces the expression levels of both KLF5 and EGR1."

“As we begin a new year filled with possibility and promise, the Office for Research and Innovation and Intellectual Property Partners (IPP) proudly celebrate all Stony Brook University inventors who dare to shape the future. Through dedication, ingenuity, and perseverance, they are transforming groundbreaking ideas into reality, embodying the spirit of innovation that defines our institution." - Office for Research and Innovation and Intellectual Property Partners

Dr. Vincent Yang
^{Vincent Yang, M.D., Ph.D., Simons Chair of Medicine}

^{Agnieszka Bialkowska, Ph.D., Associate Professor of Medicine}