A Graded Neonatal Mouse Model of Necrotizing Enterocolitis Demonstrates That Mild Enterocolitis Is Sufficient to Activate Microglia and Increase Cerebral Cytokine Expression
Cuilee Sha, Trevor Van Brunt, Jacob Kudria, Donna Schmidt, Alisa Yurovsky, Jela Bandovic, Michael Giarrizzo, Joyce Lin, Styliani-Anna Tsirka, Agnieszka B. Bialkowska, Lonnie P. Wollmuth, Esther M. Speer, Helen Hsieh
Abstract
Necrotizing enterocolitis (NEC) is an inflammatory gastrointestinal process that afflicts approximately 10% of preterm infants born in the United States each year, with a mortality rate of 30%. NEC severity is graded using Bell’s classification system [....] READ MORE
Winners of the 2024 SEED Grant
- Role of GCSF and Microglia Interactions in NEC-Induced Neuroinflammation on Neurodevelopment. Helen Hsieh, Lonnie Wollmuth.
- Dynamic Remodeling of Thrombi: Novel Insights through FAPI-PET Imaging for Thrombosis in Animal Models and Cellular Analysis. Nicos Labropoulos, Nashaat Turkman, Wei Yin.
- Ex vivo effects of superficial skin peeling agents on middle ear structures and cholesteatoma. Huseyin Isildak.
