Anat Biegon, Ph.D.
• Professor of Radiology and Neurology
• Primary Department, Radiology
Education:
• Postdoc, Neuroendocrinology, Rockefeller University, NYC, NY
• Ph.D, Neurobiology, Weizmann Institute of Science Rehovot, Israel
• Masters, Biochemistry, Tel Aviv University, Israel
• BS, Chemistry, Tel Aviv University, Israel
Research Interests:
Dr. Anat Biegon is Professor of Radiology (primary) and Neurology at Stony Brook University Renaissance School of Medicine.
Awards and Recognitions:
Professor Anat Biegon has received many grants including Alzheimer Foundation “Part The Cloud” (PI Biegon) Aromatase inhibition in Alzheimer's disease: Phase 2 study, 1R01AG074221-01 (PI Sundermann) Role: Co-I "Sex Differences in the Clinical Expression of Alzheimer's Disease Neuropathology and Their Underlying Biological Mechanisms," R21MH117582 "Brain Aromatase and Inhibitory Control in Bulimia Nervosa."
In 2021, Dr. Biegon has organized a virtual international conference on women's health (The long Road to equity for women in Medicine, which you may access here.
Research:
- Professor Anat Biegon research interests include:
- Brain response to traumatic, ischemic or inflammatory insults
- Sex differences and gonadal hormone modulation of brain function in health and disease
- Development and validation of radiopharmaceuticals for non-invasive imaging of neurotransmitter and hormone markers in brain disorders and cancer
Active protocols:
- Neuroinflammation and Cognitive Impairment Following Traumatic Brain Injury (TBI) of Domestic Violence Shelter Residents: A PET/MRI study
- Imaging inflammation in the spine: PET/MRI studies with [18F]FEPPA
- Brain Aromatase and Inhibitory Control in Bulimia Nervosa (with T. Hildebrandt, Mount Sinai SOM).
Journal Papers:
Dr. Anat Biegon has exceptional journal papers including:
Raizman R, Tavor I, Biegon A, Harnof S, Hoffmann C, Tsarfaty G, Fruchter E, Tatsa-Laur L, Weiser M, Livny A. Traumatic Brain Injury Severity in a Network Perspective: A Diffusion MRI Based Connectome Study. Sci Rep. 10(1):9121. doi: 10.1038/s41598-020-65948-4. (2020)
Biegon A, Alia-Klein N, Alexoff DL, Fowler JS, Kim SW, Logan J, Pareto D, Preston-Campbell R, Wang GJ, Hildebrandt T. Relationship of estrogen synthesis capacity in the brain with obesity and self-control in men and women. Proc Natl Acad Sci USA. 2020 Sep 15;117(37):22962-22966. doi: 10.1073/pnas.2006117117. Epub 2020 Aug 31.PMID: 32868418
Alia-Klein N, Preston-Campbell RN, Kim SW, Pareto D, Logan J, Wang GJ, Scott J. Moeller SJ, Fowler JS and Biegon A. Human Cognitive Ability is Modulated by Aromatase Availability in the Brain in a Sex-Specific Manner. Frontiers in Neuroscience 2020 Oct 19;14: 565668. doi: 10.3389/fnins.2020.565668 eCollection (2020)PMID: 33192252
Sundermann, EE, Maki, PM, Reddy S, Bondi, MW, Biegon A. Women’s higher brain metabolic rate compensates for early Alzheimer’s pathology.Alzheimer's Disease Neuroimaging Initiative. Alzheimers Dement (Amst). 2020 Nov 20;12(1):e12121. doi: 10.1002/dad2.12121. eCollection 2020. PMID: 33251322
Biegon A. Considering Biological Sex in Traumatic Brain Injury. Front Neurol. 2021 Feb 10;12:576366. doi: 10.3389/fneur.2021.576366 eCollection 2021. PMID: 33643182
Biegon A, Sundermann E. Editorial: Considering Biological Sex in Neurological Research. Front Neurol. 2021 Jul 2;12:698492. doi: 10.3389/fneur.2021.698492. eCollection(2021) PMID: 34276546
Wang Z, CaoX, LaBella A, Zeng X, Biegon A, Franceschi D, Petersen E, Clayton N, Ulaner GA, Zhao W and Goldan AH. High Resolution and High Sensitivity PET for Quantitative Molecular Imaging of the Monoaminergic Nuclei: A GATE Simulation Study. Medical Physics 2022 Jul;49(7):4430-4444. doi: 10.1002/mp.15653. Epub 2022 May 15. PMID: 35390182.
Conference Papers and Abstracts:
Some of Dr. Anat Biegon conference papers and abstract include:
Airola K, Franceschi D, Cohen J, Yaffe M, Schweitzer M, Li H, Huang C, Fisher P, Biegon A. Local Aromatase Expression in the Breast is Linked to Breast Density. WMIC virtual meeting abst. GA441 (2020)
Petersen E, Neilson P, LaBella A, Howansky A, Cao X, Wang Z, Woody C, Biegon A, Rahmim A, Zhao W and Goldan A. Performance simulation of high resolution and high sensitivity Prism-PET brain scanner. Journal of Nuclear Medicine 61 (s1) 1502 (2020).
Wang Z, Cao X, Zeng X, Andy LaBella A, Petersen E, Clayton N, Biegon A, Zhao W and Goldan A. A high resolution and high sensitivity Prism-PET brain scanner with non-cylindrical decagon geometry. Journal of Nuclear Medicine 62 (s1) 1136 (2021).
Biegon A, Shroyer KR, Franceschi D, Dhawan J, Tahmi M, Pareto D, Bonilla P, Airola K, Cohen J. Initial studies with [11C]vorozole positron emission tomography detect over-expression of intra-tumoral aromatase in breast cancer. J Nucl Med. 61:807-813 (2020)
E-Books:
Biegon A, Sundermann E., Coyle P. and P., Editors. Considering Biological Sex in Neurological Research. Front Neurol. 2021 Editorial: Biegon A, Sundermann E. Considering Biological Sex in Neurological Research. Front Neurol. 12:698492. (2021)
Biegon A. and Seeman, M. Editors. Personalizing Medicine by Sex, Gender and Hormonal Status: Progress, Opportunities and Challenges. J. Personalized Medicine (2021)
Lab Members:
• Jasbeer Dhawan, Ph.D.
• William Scherl, MS
Contact Information:
Stony Brook Medicine
Department of Radiology
HSC Level 4, Room 120
Stony Brook, NY 11794-8460
Phone: 631-632-6228
Fax: 631-444-7538
Email: anat.biegon@stonybrookmedicine.edu
