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Laboratories

  • SB Radiology Advanced Research Imaging Center: Radiology Advanced Imaging Research Center provides imaging support for biomedical research community @ SB. We encourage collaborations across research disciplines through inclusion of imaging. We work with colllaborators to explore new imaging techniques and protocols as well as new imaging applications. We also provide training to enhance biomedical imaging research. We have a comprehensive state-of-the-art biomedical imaging infrastructure for carrying out clinical research. The major infrastructure includes 3T PRISMA MRI scanner, MRI-PET Siemen scanner, 3T Siemen Skyra, PET/CT, and radiochemistry laboratories, which peripheral supportive infrastructure to support a wide range of human studies and clinical trials. Please contact tim.duong@stonybrookmedicine.edu for more information and logistics. 
  • Preclinical MRI laboratory, led by Dr. Tim Duong. This laboratory houses two small animal 7.0 Tesla and 9.4 Tesla MRI scanner with Bruker ADVANCE III. It has a assortment of vendor and custom-made RF coils for 1H and X nuclide experiments and assortment of holder and support for mouse and rodent experiments. This system has up-to-date hardware and software for structural, physiology, and functional, and spectroscopic imaging. There is also peripheral monitoring equipment to support a range of animal stuies. Our animal MRI scanners also house unique PET inserts for simultaneous PET and MRI acquisitions. 
  • Preclinical PET/SPECT/CT laboratory, led by Dr. Paul VaskaOur preclinical imaging facility also houses a trimodality PET/SPECT/CT (Siemens Inveon), a top-tier small-animal imaging platform located in a spacious lab in the main animal facility.  All 3 modalities can be accessed in a sequential manner, without removing the animal from the bed, thus providing a high degree of image registration. The PET component features a large field of view (9.9 cm transaxial x 12.7 cm axial), high spatial resolution (1.5 mm FWHM), and high sensitivity (6.8% coincidence).  The CT component provides anatomical information as well as attenuation correction for the PET.  It also has fully developed data processing software with all necessary quantitative corrections and multiple image reconstruction options (FBP, OSEM, MAP).  The lab includes a new Biodex Atomlab 500 dose calibrator and well counter system, and standard equipment for handling blood samples.
  • The Digital Radiological Imaging Laboratory (DRIL), led by Dr. Wei Zhao, is working to develop new detector technologies for medical imaging and to investigate their performance in advanced clinical applications. The group investigates imaging performance and design optimization for amorphous selenium flat-panel detectors for digital mammography and digital breast tomosynthesis, as well as advanced detector concepts for improved imaging performance at low dose and high frame rates
  • Laboratory for Imaging Research and Informatics (IRIS), led by Dr. Jerome Liang, has developed numerous algorithms for (1) reconstructions of quantitative single photon emission computed tomography (SPECT), high resolution positron emission tomography (PET) and low-dose computed tomography (CT), (2) segmentation of multi-spectral magnetic resonance (MR) and CT images, (3) registration of dynamically acquired MR scans from moving and deformable organs, and (4) feature extraction and classification for computer aided detection (CADe) and diagnosis (CADx).
  • The Medical Image Research and Analysis (MIRA) Laboratory, led by Dr. Chuan Huang, conducts research in medical imaging technologies including Magnetic Resonance Imaging (MRI), Positron Emission Tomography (PET), Single Photo Emission Computed Tomography (SPECT), simultaneous PET/MRI and their applications in psychiatric disorders, neurological diseases, cancer, cardiac diseases, etc. This lab is particularly interested in imaging-guided precision medicine (treatment prediction, treatment response early detection, and medical imaging guided treatment selection) and understanding the biology using medical imaging.
  • Stroke and TBI imaging and neuroprotection laboratory, led by Zhao (John) Jiang. This laboratory uses imaging techniques to investigate stroke and TBI pathophysiology and evaluate neuroprotective treatments. Collaborative measures include histology, immunohistochemistry, and behavioral function. 
  • Ophthalmologic Imaigng laboratory, led by Eric Muir. This laboratory develops and applys imaging techniques to investigate retinal and ophthalmologic pathophysiology and evaluate neuroprotective treatments. Collaborative measures include histology, ERG, optomotry, and behavioral function.