Preclinical MRI

Preclinical MRI Center
Strives to provide imaging support for biomedical research. We encourage a wide range of collaborations between various groups to explore new imaging techniques, novel imaging contrast agents, or new applications in various research fields. It houses two state-of-the-art animal scanners:

Bruker 7.0 Tesla MRI, 
Bruker 9.4 Tesla MRI. 
Computational infrastructure to assist image analysis. 
High-resolution PET insert for simultaneous MRI-PET study. 
Supportive infrastructure:
Peripheral equipment offers necessary support for anesthesia, physiological monitoring, stimulus presentations
Surgical suites,
Behavioral testing suites,
Wet labs for histology and immunohistochemistry,
Machine shop and RF electronic shop, etc. 

Contacts Tim Duong, PhD (Director) or Zhao (John) Jiang, MD/PhD (Manager).
Pilot and matching funds availables. 

Our imaging expertise includes: 

  • T1, T2, spin-density T1rho structural MRI,
  • diffusion-tensor imaging, 
  • functional MRI (fMRI), 
  • resting-state fMRI (rsfMRI), 
  • arterial spin labeling, 
  • susceptibility weighted imaging, 
  • dynamic contrast enhanced MRI, 
  • dynamic susceptibility enhanced MRI, 
  • quantitative BOLD fMRI (qBOLD),
  • intravoxel incoherent motion (IVIM),
  • fat imaging,
  • metabolic imaging,
  • MR spectroscopy (MRS),
  • combined MRI/PET.

We also collaborate closely with clinicians to study a range of diseases, including

  • multiple sclerosis, 
  • cancer (breast, neuro, prostate, soft tissue)
  • stroke, 
  • TBI,
  • diabetic retinopathy,
  • glaucoma.

We also apply imaging technologies to evaluate innovative treatment strategies. In addition to MRI, we also have expertise in behavioral measures, functional outcome measures, image analysis, immunohistology.