Jun Lin, MD, PhD, FASA

Professor

Phone: 631-444-2975
Email
Research webpage
Stony Brook Medicine Profile
  • Education  
  • M.B.B.S., Sun Yat-sen University of Medical Sciences, Guangzhou, China
  • M.Sc., Pharmacology, Sun Yat-sen University of Medical Science, China
  • Ph.D., Biomedical Science, Mount Sinai School of Medicine, NY
  • Residency Anesthesiology, Montefiore Medical Center, Albert Einstein College of Medicine, NY
  • Fellowship Pharmacology, Mount Sinai School of Medicine, NY
  • Research Interests  
  • Inhibition of Cancer Cell Proliferation by Anesthetics
  • Publications  
  • PubMed Search
  • Velickovic I, Dalloul M, Wong KA, Bakare O, Schweis F, Garala M, Alam A, Medranda G, Lekovic J, Shuaib W, Tedjasukmana A, Little P, Hanono D, Wijetilaka R, Weedon J, Lin J, Toledano RD, Zhang M.
    Complement factor B activation in patients with preeclampsia.
    J Reprod Immunol. 2015 Jun;109:94-100
  • Lin J, Benditt DG, Lu F.
    Clinical pharmacology of anesthetic agents and their application in clinical electrophysiologic procedures.
    In: Interventional Cardiac Electrophysiology. S Saksena, et al, eds. Minneapolis: Cardiotext Publishing, pp. 267-80, 2015
  • Leng T, Gao X, Dilger JP, Lin J.
    Neuroprotective effect of lidocaine: is there clinical potential?
    Int J Physiol Pathophysiol Pharmacol. 2016 Apr 25;8(1):9-13
  • Lin J, Xiong ZG.
    TRPM7 is a unique target for ischemic brain injury.
    Proc Neurosci 2016 1(1):1-5
  • Chen J, Dou Y, Zheng X, Leng T, Lu X, Ouyang Y, Sun H, Xing F, Mai J, Gu J, Lu B, Yan G, Lin J, Zhu W.
    TRPM7 channel inhibition mediates midazolam-induced proliferation loss in human malignant glioma.
    Tumour Biol. 2016 Nov;37(11):14721-14731
  • Leng T, Lin S, Xiong Z, Lin J.
    Lidocaine suppresses glioma cell proliferation by inhibiting TRPM7 channels.
    Int J Physiol Pathophysiol Pharmacol. 2017 Apr 15;9(2):8-15
  • Lin J.
    Substance Abuse.
    In: Chestnut Anesthesia Principles and Practice, Chinese Translation, 5th Edition (People’s Medical Publishing House, Beijing).
  • Li R, Xiao C, Liu H, Huang Y, Dilger JP, Lin J.
    Effects of local anesthetics on breast cancer cell viability and migration.
    BMC Cancer. 2018 Jun 19;18(1):666.
  • Li R, Liu H, Dilger JP, Lin J.
    Effect of propofol on breast cancer cell, the immune system, and patient outcome.
    BMC Anesthesiol. 2018 Jun 26;18(1):77.
  • Du XJ, LiXM, Cai LB, Sun JC, Wang SY, Wang XC, Pang XL, Deng ML, Chen FF, Wang ZQ, Chen FR, Zhang HH, Wang HY, Piedra P, Chen ZP, Lin J, Wu SX.
    Efficacy and safety of nimotuzumab in addition to radiotherapy and temozolomide for cerebral glioblastoma: a phase II multicenter clinical trial.
    J Cancer 2019; 10(14):3214-3223.
  • Jin Z, Li R, Liu J, Lin J.
    Long-term prognosis after cancer surgery with inhalational anesthesia and total intravenous anesthesia: a systematic review and meta-analysis.
    Int J Physiol Pathophysiol Pharmacol. 2019 Jun 25;11(3):83-94.
  • Jin Z, Lin EJ, He Y, Lin J.
    Intraoperative methadone for postoperative pain management - systematic review protocol.
    Int J Physiol Pathophysiol Pharmacol. 2019 Oct 15;11(5):220-223.
  • Liu H, Dilger JP, Lin J.
    The Role of Transient Receptor Potential Melastatin 7 (TRPM7) in Cell Viability: A Potential Target to Suppress Breast Cancer Cell Cycle.
    Cancers (Basel). 2020 Jan 4;12(1).
  • Jin Z, Liu J, Li R, Gan TJ, He Y, Lin J.
    Single injection Quadratus Lumborum block for postoperative analgesia in adult surgical population: A systematic review and meta-analysis.
    J Clin Anesth. 2020 Jan 19;62:109715.
  • Li R, Huang Y, Lin J.
    Distinct effects of general anesthetics on lung metastasis mediated by IL-6/JAK/STAT3 pathway in mouse models.
    Nat Commun. 2020 Jan 31;11(1):642.
  • Jin Z, Li R, Gan TJ, He Y, Lin J.
    Pectoral Nerve (PECs) block for postoperative analgesia-a systematic review and meta-analysis with trial sequential analysis.
    Int J Physiol Pathophysiol Pharmacol. 2020 Feb 25;12(1):40-50.
  • Liu H, Dilger JP, Lin J.
    Effects of local anesthetics on cancer cells.
    Pharmacol Ther. 2020 Apr 25:107558.
  • Recent Presentations   
  • Leng T, Xiao C, Xiong Z, Lin J .
    Proliferation of C6 glioma cells is regulated by Transient Receptor Potential Melastatin 7 channels.
    IARS 2016
  • Chen J, Xiao C, Dou Y, Zhu W, Lin J.
    Midazolam induced proliferation loss in human glioblastoma by suppressing TRPM7 channels.
    IARS 2016
  • Liao S, Xiao C, Zheng W, Lin J.
    PI3K/AKT mediates lidocaine protecting rat PC12 cells from amyloid-beta toxicity.
    IARS 2016
  • Chakraborty S, Xiao C, Dilger JP, Lin J.
    Lidocaine alters migration and TRPM7 channel expression of human A549 lung cancer cells.
    IARS 2016
  • Xiao C, Dilger JP, Lin J.
    Inhibition of breast cancer cells by local anesthetics.
    IARS 2016
  • Holiprosad D, Etwaru K, Xiao C, Dilger JP, Lin J.
    Inhibition of TRPM7 channels in HEK-293 cells by local anesthetics.
    IARS 2016
  • Xiao C, Chakraborty S, Dilger JP, Lin J.
    Local anesthetics inhibited breast cancer cell growth.
    IARS 2016
  • Li R, Li M, Liu H, Huang Y, Dilger JP, Lin J.
    Comparing Volatile and Intravenous Anesthetics in a Mouse Model of Breast Cancer Metastasis.
    American Assoc for Cancer Research meeting, April 2018
  • Jaromy M, Jin Z, Li R, Lin J, Liu H.
    Effect of Sevoflurane and Propofol on the phenotype of lung cancer cell in vitro, preliminary findings.
    IARS 2019
  • Dilger JP, Jin Z, Lin J, Liu H.
    Effects of Lidocaine on Breast Cancer Cells and the Potential Role of Transient Receptor Potential Melastatin 7 (TRPM 7) .
    IARS 2019
  • Gan TJ, Jin Z, Li R, Lin J, Liu J.
    Pectoral block vs Paravertebral block: a systematic review and meta-analysis.
    IARS 2019
  • Jin Z, Lin J, Liu H, Liu J.
    Effect of Sevoflurane and Propofol on a human breast cancer cell line with tropism to brain in vitro .
    IARS 2019
  • Jin Z, Li R, Lin J, Liu J.
    Intravenous vs volatile anesthesia and breast cancer surgery outcome - a systematic review and meta-analysis.
    IARS 2019
  • Jin Z, Li R, Lin J, Liu J.
    Clinical application of quadratus lumborum: a systematic review.
    IARS 2019
  • Jin Z, Liu J, Li R, Gan TJ, He Y, Lin J.
    Pectoral block vs Paravertebral block: a systematic review and meta-analysis.
    PGA 2019
  • Lin J, Li R, Huang Y.
    Effect of general anesthetics on the tumor micro-environment in mouse models of breast cancers of spontaneous metastasis.
    Journal of Clinical Oncology. 2020 v38, no. 15_suppl
  • Lin J, Jin Z, Li R.
    The effect of regional anesthesia on cancer related outcomes after oncological surgeries: A systematic review .
    Journal of Clinical Oncology. 2020 v38, no. 15_suppl
  • Awards, Honors, Professional Appointments  
  • Elected to Association of University Anesthesiologists
  • Section Editor of the of “General Pharmacology and Pharmacokinetics” section of BMC Anesthesiology Editor-in-Chief of the International Journal of Physiology, Pathophysiology and Pharmacology
  • Journal Board (Reviewer) of Cancers