2021 Peter Glass Academic Research Evening

2021 Peter Glass Academic Research Evening
Tuesday, August 31, 2021
3:30 pm to 8:30 pm
Stony Brook Medicine, MART Building


   The 2021 Dr. Peter S.A. Glass Academic Research Evening was held on August 31. This year's event took place in a new venue - the MART Auditorium and Atrium. A total of 32 clinical research and 17 basic science posters were presented. Nine posters were selected for two Moderated Poster Sessions. View the Photo Album.

   Our Keynote Speaker was Pamela Flood, MD, MA, Professor of Anesthesiology, Perioperative and Pain Medicine at Stanford University. Dr. Flood spent the first part of her medical and scientific career at Columbia University, obtaining her MD there in 1990. She went on to do her internship and Anesthesiology Residency there and completed a Fellowship in Obstetric ​Anesthesiology in 1996. Concurrent with the fellowship, she received a MS in Neuroscience. She progressed from Assistant Professor to Associate Professor to Full Professor in Columbia's Department of Anesthesiology. In 2011, she moved to California where she worked at UCSF for two years and then became Professor Anesthesiology, Perioperative and Pain Medicine at Stanford. Somehow, she found the time to do a Fellowship in Pain Medicine at Stanford.

   Much of Dr. Flood's research focused on the role of neuronal nicotinic receptors in anesthesia and analgesia. Evidence for the importance of nicotine in analgesia has waxed and waned. In a 2014 review (PMID: 25046780), Dr. Flood wrote "while nicotine is not useful in the perioperative period, subtype-selective nicotinic modulators continue to offer potential promise to the armamentarium against acute and chronic pain". Anesthesia care during labor and delivery is another one of her research interests. And most recently, she has been interested in responses to the opioid crisis. Dr. Flood's Keynote Address was entitled "Perioperative Management of Patients with Chronic Pain".

Basic Science Moderated Poster Presentations
  • Michelino Puopolo, PhD, Associate Professor, Department of Anesthesiology “Contribution of T-type calcium channels to nociceptors’ hyperexcitability and the development of chronic neuropathic pain following spinal cord injury in rats.”
  • Anatoly Mikhailik, PhD, Senior Research Support Specialist, Department of Anesthesiology “S1 protein of SARS-CoV-2 suppress mucociliary clearance upon contact with ciliated cells of the humanized ACE2 mouse airways.”
  • Evgeny Amelchenko, PhD, Postdoctoral Associate, Department of Anesthesiology “Mapping the whole-brain circuitry of social conflict.”
  • Ru Li, PhD, Postdoctoral Associate, Department of Anesthesiology “General anesthetics on metastatic course of breast cancer cells to the brain in mouse models.”
Clinical Research Moderated Poster Presentations
  • David Komatsu, PhD, Associate Professor, Department of Orthopedics and Rehabilitation, Stony Brook University “Endocannabinoid Metabolism and Pain Following Total Knee Arthroplasty.”
  • Nicholas Browne, Medical Student “Impact of Serological and PCR Testing Requirements on the Selection of COVID-19 Convalescent Plasma Donors.”
  • Laura M. Generale, BS “Persistent polymerase chain reaction (PCR) positivity among persons recovered from COVID-19.”
  • Alex Freedenberg, Medical Student “Neutralizing Activity to SARS-CoV-2 of Convalescent and Control Plasma Used in a Randomized Controlled Trial.”
  • Elliott Bennett-Guerrero, MD, Professor and Vice Chair for Clinical Research, Department of Anesthesiology “SARS-CoV-2 Convalescent Plasma vs. Standard Plasma in COVID-19 Infected Hospitalized Patients in New York; A Double-Blind Randomized Trial.”
Poster Presentations
  • Amelchenko EM, Bezriadnov DV, Mineyeva OA, Ivanova AA, Kedrov AV, Lazutkin AA, Anokhin KV, Enikolopov GN. Elusive deficit: differential effects of gamma irradiation on neurogenesis, spatial reversal learning and context discrimination
  • Itaman S, Amelchenko E, Enikolopov G. The effect of cART drugs on adult hippocampal neurogenesis
  • Spurgat M, Zheng J, Tang S-J. Single Nuclei RNA-seq Characterization of Subpopulations of Astrocytes and Neurons in an HIV gp120 Pain Mouse Model
  • Mellanson KA, Michurina TV, Mikhailik A, Takemaru K-I, Enikolopov G, Peunova N. Activity of ciliated ependymal cells controls directional flow and polarity of the ciliated cells
  • Boakye PA, Tang S-J. Using Quadruple Whole-Cell Patch Clamp in The Dorsal Horn of The Spinal Cord to Study The Pain Circuitry in HIV/AIDS Induced Neuropathic Pain
  • Liu H, Lauzadis J, Kaczocha M, Puopolo M. Contribution of T-type calcium channels to nociceptors’ hyperexcitability and the development of chronic neuropathic pain following spinal cord injury in rats.
  • Mikhailik A, Michurina TV, Peunova N. NO regulates ciliated cell polarity, ciliary beat frequency, and flow in mouse trachea
  • Mikhailik A, Michurina TV, Peunova N. S1 protein of SARS-CoV-2 suppress mucociliary clearance upon contact with ciliated cells of the humanized ACE2 mouse airways
  • Chang Y-H, Dubnau J. Glial cells and blood brain barrier defects mediate disease progression in a Drosophila model of TDP-43 proteinopathy
  • Amelchenko E, Smagin D, Shuvaev S, Vankataraju KU, Osten P, Kudryavtseva N, Kulakov A, Enikolopov G. Mapping the whole-brain circuitry of social conflict
  • Talbot L, Ayala B, Halper D, Imperato T, Gursoy N, Treidler S, Phatnani H, Hammell M, Bowser, Bennett-Guerrero E, Dubnau J. Cerebrospinal Fluid Derived RNA Biomarkers for Improved Diagnosis of Amyotrophic Lateral Sclerosis and Related TDP-43 Proteinopathies
  • Krupp S, Azpurua J, Chang Y-H, Elkarim E, Tranquille M, Dubnau J . A behavioral suppressor screen and glial cell-type specific RNA sequencing converge onto SF2/SRSF1 as a potent suppressor of TDP-43 mediated neurodegeneration.
  • Fauzan M, Studholme K, Yu M, Oubraim S, Haj-Dahmane S, Kaczocha M. Expression & Role of Fatty Acid Binding Protein 5 in the Mouse Dorsal Striatum
  • Itaman S, Enikolopov G. Endogenous barcoding of neural stem cells in the adult brain
  • Li, R Huang Y, Dilger JP, Lin J. Sevoflurane promotes VEGF secretion and vascular permeability leading to increased lung metastasis in a mouse model of human breast cancer
  • Li R, Li X, Liu Q, Lin J. Effects of NSAIDs + β-blocker on breast cancer lung metastasis in mouse models
  • Li R, Li X, Lin J. General anesthetics on metastatic course of breast cancer cells to the brain in mouse models
  • Freedenberg AT, Pan C-H, Diehl W, Romeiser JL, Hwang G-R, Leiton CV, Muecksch F, Shroyer KR, Bennett-Guerrero E. Neutralizing Activity to SARS-CoV-2 of Convalescent and Control Plasma Used in a Randomized Controlled Trial
  • Freedenberg AT, Pan C-H, Hearing JC, Romeiser JL,Bennett-Guerrero E. Comparison of Plaque Reduction Assay to Novel Pseudovirus Assay for Measurement of Neutralizing Antibodies to SARS-CoV-2.
  • Generale LM, Shevik ME, Freedenberg AT, Carter JA, Romeiser JL, Talbot LR, Browne NJ, Cosgrove ME, Rago MG, Caravella GA, Ahmed T, Mamone LJ, Bennett-Guerrero E. Persistent polymerase chain reaction (PCR) positivity among persons recovered from COVID-19
  • Scorsese G, Parikh S, Kozlowski P, Turkiew E , Shafai A, Seiter C, Diamond P, Mena S, Cervo K, Wu D, Costa A , Romeiser JL, Bennett-Guerrero E, Factor M. CA-2 Quality Assurance & Quality Improvement Project: Narcotic Waste Process
  • Browne NJ, Carter JA, Freedenberg AT, Romeiser JL, Talbot LR, Cosgrove ME, Shevik ME, Generale LM, Rago MG, Caravella GA, Ahmed T, Mamone LJ, Bennett-Guerrero E. Impact of Serological and PCR Testing Requirements on the Selection of
  • Bennett-Guerrero E, Romeiser JL, Talbot LR, Ahmed T, Mamone LJ, Singh SM, Hearing JC. SARS-CoV-2 Convalescent Plasma vs. Standard Plasma in COVID-19 Infected Hospitalized Patients in New York; A Double-Blind Randomized Trial
  • Kimura R, Schwartz J, Romeiser JL, Senzel L, Elliott-Bennett-Guerrero. The Effect of Chamomile Intake on Blood Coagulation Tests in Healthy Volunteers
  • Singh SM, Bolze E, Bennett-Guerrero E. Creating A Novel Datamart/Tableau Dashboard To Monitor Enhanced Recovery Programs
  • Li R, Jin Z, Lin J. Combined general/epidural anesthesia vs general anesthesia on the postoperative inflammation or stress response: a systematic review and meta-analysis
  • Jin Z, Islam A, Lin J. The efficacy of liposomal bupivacaine in regional anesthesia, a systematic review
  • Jin Z, Daksla N, Schabel J, Gan TJ. Efficacy of NK-1 and 5-HT3 antagonist combination for PONV prophylaxis, a systematic review and meta-analysis
  • Jin Z, Gan S, Schabel J, Gan TJ. Efficacy of palonosetron-dexamethasone combination compared to ondansetron-dexamethasone for prophylaxis against postoperative nausea and vomiting, systematic review and meta-analysis
  • Jin Z, Li R, Lin J. The effect of regional anesthesia on cancer related outcomes after oncological surgeries- a systematic review
  • Jin Z, Li R, Lin J. Intravenous vs volatile anesthesia and colorectal cancer surgery outcome- a systematic review and meta-analysis
  • Jin Z, Lee C, Zhang K, Richman D. Utilization of wearable pedometer devices in the perioperative period- a systematic review
  • Prot S, Sugimoto K, Romeiser J, Halper D, Gan TJ, Bennett-Guerrero E. Use of Integrated Pulmonary Index to Predict Post-Operative Respiratory Adverse Events in High Risk Patients
  • Nada E, Chepanoske M, Mallairi O, Alper E, Heard S. Association between Previous Cervical Spine Fusion and Failed First Attempt at Intubation: A Retrospective Chart Review
  • Nada E, Rajpal G, Chan A, Kadiyala M, Emmerick I, Maxfield M, UY Karl, Lou F. Comparison of Ultrasound Guided versus Thoracoscopic Guided Intercostal Nerve Block with Liposomal Bupivacaine for Minimally Invasive Thoracic Surgery: A Pilot Study
  • Qureshi F, Abola R, Shah S. Review of Hospital Admissions/Emergency Department visits after surgery at Stony Brook Ambulatory Surgery Care Center
  • Qureshi F, Abola R. Peri-induction Cardiac Arrest Review
  • Kang RS, Chojnowski R, Mavarez-Martinez A, Bergese SD. Evaluation of Virtual Interviews for Anesthesiology Residency Program During COVID-19
  • Komatsu DE, Gordon CR, Ayala B, Nicholson J, Kaczocha M. Endocannabinoid Metabolism and Pain Following Total Knee Arthroplasty
   The winners of the judged moderated sessions were:
  • Best Basic Science Poster: Ru Li, PhD, Postdoctoral Associate
  • Best Clinical Science Poster: Elliott Bennett-Guerrero, MD, Professor and Vice Chair for Clinical Research
  • Best Poster Presented by a Young Researcher: Alex Freedenberg, Medical Student
Dr. TJ Gan, Dr. Pamela Flood and Dr. Steven Shafer
  Special thanks to Ms. Christine Fogarty who organized the Evening and to our guest judges, from various departments at Stony Brook:
  • Kenneth R. Shroyer, MD, PhD, The Marvin Kuschner Professor and Chair Department of Pathology, Interim Associate Director for Basic Research, Stony Brook Cancer Center
  • Scott Moeller, PhD, Associate Vice Chair for Clinical Research Assistant Professor, Department of Psychiatry and Behavioral Health
  • Ramin Parsey, MD, PhD, Chair, Department of Psychiatry and Behavioral Health
  • Marc Halterman, MD, PhD, Professor and Chairman, Department of Neurology, Co-Director, Neurosciences Institute