|Volume 33 Number 3||Stony Brook, NY||< March 2020 >|
|New Faculty: Dr. Angelo||March Calendar||STARS||Kudos|
|Visiting Professor||New Research Grants||Anesthesia Interest Groups||Retirement|
|New Publications||Where is That?||Monthly Muscle Chillaxant|
Tue. Mar 3. The Journal Club will meet at 6:00 pm at the Curry Club.
Wed. Mar 4. Dr. TJ Gan will conduct the Faculty Meeting at 7:00 am in LH5.
Wed. Mar 4. Drs. E AlBizri, R Tenure and L Ericksen will conduct the Chiefs Meeting at 7:00 am in HSC, L-3, 155.
Wed. Mar 11. Dr. Adam Wetcher will present his Senior Grand Rounds at 7:00 am in LH5.
Tues. Mar 17. Visiting Professor, Dr. Martin Angst, will speak to the residents at 5:00 pm in Anesthesiology Library.
Wed. Mar 18. Visiting Professor, Dr. Martin Angst, will present his grand rounds talk at 7:00 am in LH5.
Wed. Mar 25. Dr. Rishimani Adsumelli will chair the QA Committee meeting at 7:00 am in LH5.
Dr. Jun Lin, MD, PhD, was appointed to the Journal Board (Reviewer) of Cancers. Congratulations!
Drs. Kaczocha and Puopolo Awarded New Research Grants
James P. Dilger, PhD and Marjorie L. Lundgren, MBA
Dr. Martin Kaczocha and his colleagues Drs. Iwao Ojima (SBU Chemistry), Robert Rizzo (SBU Applied Mathematics and Statistics), and Lloyd Trotman (Cold Spring Harbor Lab) were awarded a 5-year, $4.2 million grant from the National Cancer Institute for their project "Development of the Next Generation of FABP5 Inhibitors to Treat Prostate Cancer". With their combined expertise in computer-aided drug design, medicinal chemistry, fatty-acid binding proteins, and prostate cancer biology they will synthesize inhibitors of a fatty-acid binding protein that is upregulated in prostate cancer. They will test these compounds in cell lines and also in a mouse model of prostate cancer.
Martin will also be receiving $2.3 million in NIH funding for his grant proposal "Endocannabinoid Metabolism in Acute Pain". The idea for this proposal stems from his group's observation that the levels of some endocannabinoids are raised in patients with high acute postoperative pain (Azim et al, 2018). The project will employ pharmacological and genetic approaches to test his hypotheses.
Martin, in collaboration with a colleague from the University at Buffalo, Dr. Samir Haj-Dahmane, is also funded by the NIH to study "Synaptic Transport of Endocannabinoids in the Brain". This two year project obtained $679,000 in funding.
Dr. Michelino Puopolo has received $360,000 from NY State for his proposal "Targeting CaV3.2 calcium channel to treat chronic neuropathic pain following Spinal Cord Injury (SCI)". The mechanisms that lead to SCI-pain are poorly understood. Michelino's previous work (supported by the Department of Defense) suggested a link between the spontaneous activity of some nociceptors and the development of SCI pain. His hypothesis is that the activity of T-type calcium channels is increased by injury and this leads to hyper-excitable nociceptors and ultimately to neuropathic pain. He will test this by knocking down T-type calcium channels using antisense oligonucleotides.
In collaboration with researchers from the Medical College of Wisconsin, Michelino has also received support from NIH (R61/R33) to develop peptide inhibitors of CaV3.2 calcium channels to treat neuropathic pain.
Dr. James Dilger Retires
personal communication ;)
It does feel strange writing this, but it is true, I officially retired in mid-January. The department hosted a luncheon on my behalf in February. And yet .. here I am, editing SleepTalker! What gives?? If you heard Dr. Gan speak at the luncheon, you would know that he persuaded me to stay on as both webmaster and newsletter editor for the department. Frankly, it didn't take too much persuasion. For one thing, I enjoy doing them. For another, having stimulating activities to pursue was always part of my retirement plan. This will also take the form of my continued collaboration with Dr. Jun Lin's research project and another one with Dr. Joanne Figueiredo (Smithtown High School) and Dr. Joshua Rest (USB Department of Ecology and Evolution). So, where does the retirement part fit in? Answer: these do not add up to a full-time job and, I can do them where and when I choose!
As you may know, my former lab and office space is being converted into a new seminar room for the department. But I am grateful that Dr. Gan has given me an office (next to Jun's) that I can use when I want to be on campus. That's been averaging one day per week so far. Please stop by to say "hi" if you find the door propped open! You can always contact me via email. Just remember to "leave out the medicine". In other words, I had to surrender my stonybrookmedicine.edu email address, but still have the stonybrook.edu one. (Annoyingly, just ask Marisa, Outlook mail will not reject mail addressed to me at SBM; they just won't deliver or forward it. C'mon, this is 2020, surely there has to be a way).
Thank you to everyone who came to the luncheon! [view photos] I tried to thank people personally, but I may have missed some. And thank you in advance, for continuing to contribute to SleepTalker. If you are not an established contributor, you'll make my retirement even happier by becoming one!
Where on Campus is That?
SleepTalker, the Stony Brook Anesthesiology Newsletter is published by the Department of Anesthesiology
Stony Brook Medicine, Stony Brook, NY
Tong Joo Gan, M.D., MHS, FRCA, MBA, Chairman
Editorial Board: James P. Dilger, Ph.D.; Stephen A. Vitkun, M.D., M.B.A., Ph.D.; Marisa Barone-Citrano, M.A.; Ramanjot S. Kang, M.D.