Sleeptalker June 2022

James P. Dilger, PhD

   The 2022 Dr. Peter S.A. Glass Academic Research Evening was held on May 24 at the MART Auditorium and Atrium. A total of 29 clinical research and 17 basic science posters were presented. Ten posters were selected for two Moderated Poster Sessions. View the Photo Album. (Thanks to Mr. Amith Anugu for making many of the photos!

Basic Science Moderated Poster Presentations

• Erin Sipple, PhD Student, Department of Anesthesiology “CaV3.2 Calcium Channels Drive Nociceptors’ Hyperexcitability and Chronic Neuropathic Pain Following Spinal Cord Injury in Mice.”
• Shreevidya Korada, PhD Candidate, Department of Anesthesiology “TDP-43 Pathology Causes Differential Expression of Retrotransposons in a TDP-43- Q331K Mouse Model.”
• Evgeny Amelchenko, PhD, Research Scientist, Department of Anesthesiology “Negligible Effect of Environment on Aggressive Behavior and Brain Activity Patterns in Fight-Deprived Mice.”
• Michael Spurgat, PhD Candidate, Department of Anesthesiology “Single Nuclei RNA-seq Characterization of Astrocyte Subtype Induced by HIV Viral Protein gp120.”
• Sheed Itaman, PhD Student, Department of Anesthesiology “Using Genetic Barcodes to Lineage Trace and Measure Clonality of Adult Neural Stem Cells.”

Clinical Research Moderated Poster Presentations

• Ashley Mathew, MD, Chief Resident for Medical Student Education, Department of Anesthesiology “AIRWAY: Improving Preparation for Floor Intubations.”
• Sunitha Singh, MD, Enhanced Recovery After Surgery Coordinator, Department of Perioperative Surgical Services “Improving Urinary Management in Elective Surgical Patients Within an ERAS Joint Replacement Pathway.”
• Stephen Probst, MD, Associate Professor, Associate Medical Director of Perioperative Services, Department of Anesthesiology “Does the Capnostream 20p Monitor Predict Impending Respiratory Compromise in the Early Postoperative Period?”
• Reona Kimura, BA, Medical Student “The Effect of Chamomile Intake on Blood Coagulation Factors in Healthy Volunteers.”
• Martin Kaczocha, PhD, Associate Professor, Department of Anesthesiology “Endocannabinoids and Pain After Total Knee Arthroplasty.”

Poster Presentations

• Tiffany E Angelo, Reona Kimura, Morgane Giordano-Factor, Bahaa E Daoud, Ayesha Khan, Jamie Romeiser. Randomized Double-blind clinical trial of oxytocin bolus vs infusion in elective cesarean section - INBOX study
• Ashley Mathew, Ishu Kant, Benjamin Kim, Ramanjot S. Kang, Lucas Bracero, Karim Shuaib, Carlos Figueroa, Albert Xiao, Elizabeth Watson, Saamia Alam, Christopher Gidicsin, Jamie Romeiser, Ana Costa, Elliott Bennett-Guerrero. AIRWAY: Improving Preparation for Floor Intubations
• Ana Mavarez-Martinez, Kerri Stafford, Jason Rosenfeld, Jamie Romeiser, Sergio D. Bergese,Tong J. Gan. Efficacy of Amisulpride for Treatment of Postoperative Nausea and Vomiting in Post Anesthesia Care Unit
• Elliot Turkiew, Saamia Alam, Joy Schabel. Peripartum Anesthetic Management of a Patient with Glanzmann’s Thrombasthenia
• Adam Bindelglass, Deborah Richman, Kate Cecchetto. Perioperative Approach to a Patient with Hereditary Amyloidosis
• Michael Hafeman, Yujie Jiang, Zhaosheng Jin, Christopher Seiter. Thoracic Epidural vs. Continuous Paravertebral Block for Analgesia after VATS: a Meta-analysis
• Bell J, Richman DC. Far Beyond the Nephron- Perioperative Considerations in Autosomal Dominant Polycystic Kidney Disease (ADPKD)
• David E. Komatsu, Chris R. Gordon, Ayesha Khan, James Nicholson, Elliott Bennett-Guerrero, Martin Kaczocha. Endocannabinoids and Pain After Total Knee Arthroplasty
• Aria Shafai, Eman Nada. The Use of External Oblique Intercostal Nerve Block for Post-Operative Pain Control in a Patient Undergoing Radical Nephrectomy
• Jamie Romeiser, Jane Ahn, Jerry Cuenca, Neil Daksla, Michael Hafeman, Zhaosheng Jin, Christopher Lee, Victoria Nguyen, Joshua Rismany, Kalissa Zhang, Mingxi Zhu, Ramon Abola, Eric Zabirowicz, Elliott Bennett-Guerrero. Interoperative use of muscle relaxants, reversal agents, and twitch monitors over time



• Sunitha M Singh, Syed Azim, Cynthia Murtha, Lauren Walsh, Lauren Antonelli, Donna Hoffman, James Nicholson, Elliott Bennett-Guerrero. Improving Urinary Management in Elective Surgical Patients Within an ERAS Joint Replacement Pathway
• Sunitha M Singh, Elliott Bennett-Guerrero. Enhanced Recovery After Surgery Pathways: Improving Patient Care at Stony Brook University Medical Center
• Zachary Zerrahn, Vahe S Tateosian. Incidentally Discovered Intracardiac Foreign Body in a Child
• Jane Ahn, Zhaosheng Jin, Jerry Cuenca, Tong Joo Gan, Jun Lin. Quadratus lumborum block for analgesia after renal surgeries- a systematic review and meta-analysis
• Zhaosheng Jin, Christopher Lee, Kalissa Zhang, Deborah Richman. Utilization of wearable pedometer devices in the perioperative period- a systematic review
• Z Jin, S Greenspan, Y Jiang, G Scorsese, C Seiter, J Lin. Thoracic paravertebral block versus erector spinae block for postoperative analgesia after video assisted thoracosco
• Z Jin, Y Jiang, S Greenspan, G Scorsese, C Seiter, J Lin. Paravertebral block for postoperative analgesia after video assisted thoracoscopic surgery
• Z Jin, T Meyer, J Schabel, TJ Gan. Rescue antiemetic treatment for PONV following prophylaxis- a systematic review
• Alexa Christophides, Bill Hum, Joshua Rismany, Benjamin Rismany, Zhaosheng Jin, Ana Cristina Mavarez Martinez, Sergio D Bergese. Analgesia Nociception Index and Perioperative Outcomes: A Systematic Review and Meta Analysis
• Christopher Seiter, Angela Mironis, Jorge laguer, Eric Zabirowicz, Jeremey Poppers. Non-Bacterial Thrombotic Endocarditis Precipitating Acute Embolic Stroke Following COVID-19 Infection: A Case Report
• Morgane Factor, Tiffany E Angelo, Bahaa E Daoud, Jamie Romeiser, Ayesha Khan, Alexa Christophides, Elliott Bennett-Guerrero. The Relationship Between the Nociceptive Level Index and Epidural Anesthesia in the Laboring Parturient
• Giacomo Scorsese, Yujie Jiang, Christopher Seiter, Zhaosheng Jin, Seth Greenspan, Sara Kianian, Jun Lin. The Efficacy of Serratus Anterior Plane Block for Postoperative Analgesia after Video Assisted Thoracoscopic Surgery
• Giacomo Scorsese, Shruti Parikh, Shayla Mena, Kathleen Cervo, Patrick Diamond, Paul Kozlowski, Christopher Seiter, Aria Shafai, Elliot Turkiew, Elliott Bennett-Guerrero, Jamie Lee Romeiser, Ana Costa, Morgane Factor. The Effects of Pyxis Location on the Narcotic Waste Process



• Stephen Probst, Jamie Romeiser, Kentaro Sugimoto, Andrew Sisti, Darcy Halper, Tong J Gan, Elliott Bennett-Guerrero. Does the Capnostream 20p Monitor Predict Impending Respiratory Compromise in the Early Postoperative Period?
• Derek Atkinson, Jamie L Romeiser, Ibrahim Almasry, Henry Tannous, Puja Parikh, Elliott Bennett-Guerrero. Randomized Controlled Trial of Liberal vs. Standard Fasting Instructions in Cardiac Procedures
• Kalissa Zhang, Albert Xiao, Deborah Richman. Anesthetic Management of Intrabronchial Valves
• Victoria Nguyen, Zhaosheng Jin, Syed Azim. Spinal Anesthesia for Orthopedic Surgery in a Patient with Brugada Syndrome
• Ashley Mathew, Elizabeth Watson, Victoria Nguyen, Vahe Tateosian. Airway Challenges In A Neonate With Congenital Epulis
• Reona Kimura, Jonathon Schwartz, Jamie Romeiser, Lisa Senzel, Darcy Halper, Elliott Bennett-Guerrero. The Effect of Chamomile Intake on Sleep Disturbance, Anxiety, and Gastrointestinal Symptoms in Healthy Volunteers
• Reona Kimura, Jonathon Schwartz, Jamie Romeiser, Lisa Senzel, Darcy Halper, Elliott Bennett-Guerrero. The Effect of Chamomile Intake on Blood Coagulation Factors in Healthy Volunteers
• Reona Kimura, Jonathon Schwartz, Jamie Romeiser, Lisa Senzel, Darcy Halper, Elliott Bennett-Guerrero. The Acute Effects of Chamomile Intake on Blood Coagulation Tests in Healthy Volunteers
• Reona Kimura, Jonathon Schwartz, Elliott Bennett-Guerrero. A Narrative Review on the Potential Therapeutic Benefits of Chamomile in the Acute Care Setting
• Mingxi Zhu, Eman Nada. Application of External Oblique Intercostal Muscular Nerve Block for Subcutaneous Implantable Defibrillator Pain
• Giridhar Mula, Amith Anugu, Sahana Pentyala, Vamiq M. Mustahsan, Yanming Cai, and Srinivas Pentyala. Development of large volume sample rapid biomarker detection device
• Isabel Hubbard. The effects of glial induction of the familial ALS/FTD C9orf72 repeat in Drosophila
• Sipple E, Liu H, Gunaratna K, Kaczocha M, Puopolo M. CaV3.2 calcium channels drive nociceptors’ hyperexcitability and chronic neuropathic pain following spinal cord injury in mice.
• Ru Li, Yujie Huang, Cindy Wu, Jun Lin. General anesthetics differentially affect endothelial cell functions
• Ru Li, Xingqi Li, Jun Lin. General anesthesia promoted brain metastasis of breast cancers by inducing MMP-3 production



• Faniya Doswell, Diane Bogdan, Keith Studholme, Martin Kaczocha. Macrophage-Fatty Acid Binding Protein 5 Modulation of Inflammation
• Xufeng Chen, Shao-Jun Tang. Neural circuit polarization (NCP) in the pathogenesis of HIV-associated pain
• S Korada, O Tam, M Hammell, D Willbold, J. Dubnau. TDP-43 pathology causes differential expression of retrotransposons in a TDP-43- Q331K mouse model.
• Michael Spurgat, Junying Zheng, Shao-Jun Tang. Single Nuclei RNA-seq Characterization of Astrocyte Subtype Induced by HIV Viral Protein gp120
• Lillian Talbot, Ayesha Khan, Theresa Imperato, Nurcan Gursoy, Simona Treidler, Hemali Phatnani, Molly Hammell, Robert Bowser, Elliott Bennett-Guerrero, Josh Dubnau. Transcriptional Profiling of Cerebrospinal Fluid from Patient with Amyotrophic Lateral Sclerosis
• Anatoly Mikhailik, Tatyana Michurina, Natalia Peunova. A comprehensive approach for evaluation of the activity of mouse tracheal cilia
• Xin Liu, Shao-Jun Tang. Involvement of Wnt5a signaling chronic pain induced by NRTIs



• Mohammad Fauzan, Saida Oubraim, Mei Yu, Sherrye T Glaser, Martin Kaczocha, and Samir Haj-Dahmane. Fatty acid binding protein 5 modulates brain endocannabinoid tone and retrograde signaling in the striatum
• Sheed Itaman, Grigori Enikolopov. Using genetic barcodes to lineage trace and measure clonality of adult neural stem cells
• Sheed Itaman, Evgeny Amelchenko, Grigori Enikolopov. The effects of chronic administration of combined antiretroviral therapy (cART) on neurogenesis, behavior, and neuronal activation
• Evgeny Amelchenko, Dmitry Smagin, Sergey Shuvaev, Pavel Osten, Natalia Kudryavtseva, Alexei Koulakov, Grigori Enikolopov. Negligible effect of environment on aggressive behavior and brain activity patterns in fight-deprived mice

   Our Keynote Speaker was Harold L. Paz, MD, MS, Executive Vice President for Health Sciences, Stony Brook University Chief Executive Officer, Stony Brook University Medicine.

   Dr. Paz received his bachelor’s degree from the University of Rochester, a master of science in life science engineering from Tufts University and his medical degree from the University of Rochester School of Medicine and Dentistry. He completed his residency at Northwestern University, where he served as chief medical resident. Dr. Paz was a Eudowood Fellow in pulmonary and critical care medicine at Johns Hopkins Medical School. In addition, he was a postdoctoral fellow in environmental health science at Johns Hopkins School of Hygiene and Public Health.

   Dr. Paz is a nationally renowned healthcare leader with a unique combination of expertise in both academic medicine and industry. Prior to coming to Stony Brook last October, he was Executive Vice President and Chancellor for Health Affairs at The Ohio State University and Chief Executive Officer of the Ohio State Wexner Medical Center. His other experience includes serving as Dean and Chief Executive Officer Dean and Chief Executive Officer at Rutgers Robert Wood Johnson Medical School; Chief Executive Officer, Senior Vice President for Health Affairs and Dean Chief Executive Officer at Penn State Hershey Medical Center and Health System; and Executive Vice President and Chief Medical Officer at Aetna, Inc.

   Dr. Paz's Keynote Address was entitled "Moving to the Third Curve of Healthcare".

   The winners of the judged moderated sessions were:

  Special thanks to Ms. Christine Fogarty who organized the Evening and to our guest judges, from various departments at Stony Brook:

• Styliani-Anna (Stella) E. Tsirka, PhD, Distinguished Professor of Pharmacological Sciences, Vice Dean for Faculty Affairs
• Alfredo Fontanini, MD, PhD, Professor and Chair, Department of Neurobiology and Behavior, Vice Provost for Research and Infrastructure
• Annie Laurie Shroyer, PhD, Professor, Vice Chair for Research, Department of Surgery
• Hal Skopicki, MD, PhD, Ambassador Charles A. Gargano Chair of Cardiology, Co-Director, Stony Brook Heart Institute, Associate Professor of Medicine with Tenure

   The May 16th issue of Stony Brook Health Beat included an article "Seven Clinicians Graduate from First SUNY Clinical Leadership Academy". The Academy aims to support the development of high-potential physicians to serve as physician leaders who will then support SUNY’s academic medical centers. Two members of our department graduated. Congratulations!

• Dr. Thomas Corrado, Assistant Professor of Anesthesiology, Medical Director of Perioperative Services, Mentor: Dr. Sergio Bergese
• Dr. Stephen Probst, Associate Professor of Anesthesiology, Division Chief of Neuroanesthesia/ENT Anesthesia, Mentor: Dr. Kenneth Rosenfeld

Jeremy S. Poppers, MD PhD, FASE

   Today (June 9), is match day...
   Dr. Giacomo "Jack" Scorsese will be a Cardiothoracic Anesthesiology Fellow at Mount Sinai in NYC
   Dr. Christopher "m'kay" Seiter will be a Cardiothoracic Anesthesiology Fellow at Vanderbilt
   Please join me in wishing these gentlemen congratulations!!

Anesthesia Technology Graduation

Stephen A. Vitkun, MD, MBA, PhD

   Congratulations to the Anesthesia Technology Class of 2022! The class received their Bachelor of Science Degrees in Health Sciences at the graduation ceremony on Fri May 20th. These students took the anesthesia technology concentration, and all but one will be joining us in the ORs in September for the clinical internship program. One student was just commissioned as a Lieutenant in the US Army and will be deployed overseas in the next few months.

Recent Meetings

Awards 2022

   The Annual Resident/Teaching Awards were presented at Grand Rounds on June 1.

• Palaniappan D, Friedlander D, Desai A. Is it time to reconsider the routine blind insertion of double lumen endobronchial tubes? J Clin Anesth. 2022 Aug;79:110766
• Wu ZX, Teng QX, Yang Y, Acharekar N, Wang JQ, He M, Yoganathan S, Lin J, Wang J, Chen ZS. MET inhibitor tepotinib antagonizes multidrug resistance mediated by ABCG2 transporter: In vitro and in vivo study. Acta Pharm Sin B. 2022 May;12(5):2609-2618
• Bogdan DM, Studholme K, DiBua A, Gordon C, Kanjiya MP, Yu M, Puopolo M, Kaczocha M. FABP5 deletion in nociceptors augments endocannabinoid signaling and suppresses TRPV1 sensitization and inflammatory pain. Sci Rep. 2022 Jun 2;12(1):9241
• Mustahsan VM, He G, Helguero CG, Blum CL, Komatsu DE, Pentyala S, Kao I, Khan F. Novel Positioning Feedback System as a Guidance in Bone Tumor Resection. Surg Innov. 2022 Jun 3

Dates: Thursday, June 2, 2022 and Thursday, June 16, 2022
Time: 5:30 pm – 6:30 pm
Place: Anesthesiology Large Conference Room 4-085
Space is limited. To reserve your spot, please contact
Christine at Christine.fogarty@stonybrookmedicine.edu.

What are some benefits of practicing yoga?
 • Increased flexibility
 • Improves energy levels
 • Weight reduction
 • Mental clarity, calmness and relaxation of the mind.

What should I bring?
  Everyone will need to bring their own yoga mat, towel, and water.

What should I expect?
  Each class is 6o minutes. We will start class with a breathing exercise to calm the body and mind, to create a sense of peacefulness in the room. From there, we will move through a variety of yoga postures.

What if I’ve never practiced yoga before?
  If this is your first class, it’s important to listen to your body and go at your own pace. Remember, you never want to force a posture, we are all different and need to respect where we are in the moment. Every practice is different.